Found 10 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Aromatase
(Homo sapiens (Human)) | BDBM50006551
((+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-...)Show InChI InChI=1S/C17H22N2O2/c18-14-8-6-13(7-9-14)17(12-4-2-1-3-5-12)11-10-15(20)19-16(17)21/h6-9,12H,1-5,10-11,18H2,(H,19,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Universität des Saarlandes
Curated by ChEMBL
| Assay Description Concentration of the compound inhibiting Aromatase |
J Med Chem 35: 2210-4 (1992)
BindingDB Entry DOI: 10.7270/Q26972HS |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50006552
(3-(4-Amino-phenyl)-3-cyclopentyl-piperidine-2,6-di...)Show InChI InChI=1S/C16H20N2O2/c17-13-7-5-12(6-8-13)16(11-3-1-2-4-11)10-9-14(19)18-15(16)20/h5-8,11H,1-4,9-10,17H2,(H,18,19,20) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universität des Saarlandes
Curated by ChEMBL
| Assay Description Concentration of the compound inhibiting Aromatase |
J Med Chem 35: 2210-4 (1992)
BindingDB Entry DOI: 10.7270/Q26972HS |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50006551
((+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-...)Show InChI InChI=1S/C17H22N2O2/c18-14-8-6-13(7-9-14)17(12-4-2-1-3-5-12)11-10-15(20)19-16(17)21/h6-9,12H,1-5,10-11,18H2,(H,19,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universität des Saarlandes
Curated by ChEMBL
| Assay Description Concentration of the compound inhibiting Aromatase |
J Med Chem 35: 2210-4 (1992)
BindingDB Entry DOI: 10.7270/Q26972HS |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50006551
((+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-...)Show InChI InChI=1S/C17H22N2O2/c18-14-8-6-13(7-9-14)17(12-4-2-1-3-5-12)11-10-15(20)19-16(17)21/h6-9,12H,1-5,10-11,18H2,(H,19,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universität des Saarlandes
Curated by ChEMBL
| Assay Description Inhibition of bovine adrenal desmolase |
J Med Chem 35: 2210-4 (1992)
BindingDB Entry DOI: 10.7270/Q26972HS |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50406639
(AMINOGLUTETHIMIDE | CHEMBL2051951)Show InChI InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)/t13-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Similars
| PubMed
| n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universität des Saarlandes
Curated by ChEMBL
| Assay Description Concentration of the compound inhibiting Aromatase |
J Med Chem 35: 2210-4 (1992)
BindingDB Entry DOI: 10.7270/Q26972HS |
More data for this Ligand-Target Pair | |
Cholesterol side-chain cleavage enzyme, mitochondrial
(Bos taurus (Bovine)) | BDBM9460
(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)Show InChI InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universität des Saarlandes
Curated by ChEMBL
| Assay Description Inhibition of bovine adrenal desmolase |
J Med Chem 35: 2210-4 (1992)
BindingDB Entry DOI: 10.7270/Q26972HS |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM9460
(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | 3...)Show InChI InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PubMed
| n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universität des Saarlandes
Curated by ChEMBL
| Assay Description Concentration of the compound inhibiting Aromatase |
J Med Chem 35: 2210-4 (1992)
BindingDB Entry DOI: 10.7270/Q26972HS |
More data for this Ligand-Target Pair | |
Cholesterol side-chain cleavage enzyme, mitochondrial
(Bos taurus (Bovine)) | BDBM50006551
((+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-...)Show InChI InChI=1S/C17H22N2O2/c18-14-8-6-13(7-9-14)17(12-4-2-1-3-5-12)11-10-15(20)19-16(17)21/h6-9,12H,1-5,10-11,18H2,(H,19,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 6.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universität des Saarlandes
Curated by ChEMBL
| Assay Description Inhibition of bovine adrenal desmolase |
J Med Chem 35: 2210-4 (1992)
BindingDB Entry DOI: 10.7270/Q26972HS |
More data for this Ligand-Target Pair | |
Cholesterol side-chain cleavage enzyme, mitochondrial
(Bos taurus (Bovine)) | BDBM50006551
((+)3-(4-Amino-phenyl)-3-cyclohexyl-piperidine-2,6-...)Show InChI InChI=1S/C17H22N2O2/c18-14-8-6-13(7-9-14)17(12-4-2-1-3-5-12)11-10-15(20)19-16(17)21/h6-9,12H,1-5,10-11,18H2,(H,19,20,21) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | 6.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universität des Saarlandes
Curated by ChEMBL
| Assay Description Inhibition of bovine adrenal desmolase |
J Med Chem 35: 2210-4 (1992)
BindingDB Entry DOI: 10.7270/Q26972HS |
More data for this Ligand-Target Pair | |
Aromatase
(Homo sapiens (Human)) | BDBM50406640
(AMINOGLUTETHIMIDE | CHEMBL1394757)Show InChI InChI=1S/C13H16N2O2/c1-2-13(8-7-11(16)15-12(13)17)9-3-5-10(14)6-4-9/h3-6H,2,7-8,14H2,1H3,(H,15,16,17)/t13-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 3.70E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universität des Saarlandes
Curated by ChEMBL
| Assay Description Concentration of the compound inhibiting Aromatase |
J Med Chem 35: 2210-4 (1992)
BindingDB Entry DOI: 10.7270/Q26972HS |
More data for this Ligand-Target Pair | |