Found 46 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173019
(4-(4-(4-tert-butylphenylamino)phthalazin-1-yl)benz...)Show SMILES CC(C)(C)c1ccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)cc1 Show InChI InChI=1S/C25H24N4O/c1-25(2,3)18-12-14-19(15-13-18)27-24-21-7-5-4-6-20(21)22(28-29-24)16-8-10-17(11-9-16)23(26)30/h4-15H,1-3H3,(H2,26,30)(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173031
(4-(4-(4-bromophenylamino)phthalazin-1-yl)benzamide...)Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(Br)cc2)c2ccccc12 Show InChI InChI=1S/C21H15BrN4O/c22-15-9-11-16(12-10-15)24-21-18-4-2-1-3-17(18)19(25-26-21)13-5-7-14(8-6-13)20(23)27/h1-12H,(H2,23,27)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173045
(4-(4-(4-tert-butylphenylamino)phthalazin-1-yl)-N-m...)Show SMILES CNC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(cc2)C(C)(C)C)c2ccccc12 Show InChI InChI=1S/C26H26N4O/c1-26(2,3)19-13-15-20(16-14-19)28-24-22-8-6-5-7-21(22)23(29-30-24)17-9-11-18(12-10-17)25(31)27-4/h5-16H,1-4H3,(H,27,31)(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173049
(4-(4-(4-(chlorodifluoromethoxy)phenylamino)phthala...)Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12 Show InChI InChI=1S/C22H15ClF2N4O2/c23-22(24,25)31-16-11-9-15(10-12-16)27-21-18-4-2-1-3-17(18)19(28-29-21)13-5-7-14(8-6-13)20(26)30/h1-12H,(H2,26,30)(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173007
(4-[4-(4-Chloro-phenylamino)-phthalazin-1-yl]-benzo...)Show SMILES COC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(Cl)cc2)c2ccccc12 Show InChI InChI=1S/C22H16ClN3O2/c1-28-22(27)15-8-6-14(7-9-15)20-18-4-2-3-5-19(18)21(26-25-20)24-17-12-10-16(23)11-13-17/h2-13H,1H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173022
(3-(4-(4-tert-butylphenylamino)phthalazin-1-yl)benz...)Show SMILES CC(C)(C)c1ccc(Nc2nnc(-c3cccc(c3)C(N)=O)c3ccccc23)cc1 Show InChI InChI=1S/C25H24N4O/c1-25(2,3)18-11-13-19(14-12-18)27-24-21-10-5-4-9-20(21)22(28-29-24)16-7-6-8-17(15-16)23(26)30/h4-15H,1-3H3,(H2,26,30)(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173034
(4-(4-(3-tert-butylphenylamino)phthalazin-1-yl)benz...)Show SMILES CC(C)(C)c1cccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)c1 Show InChI InChI=1S/C25H24N4O/c1-25(2,3)18-7-6-8-19(15-18)27-24-21-10-5-4-9-20(21)22(28-29-24)16-11-13-17(14-12-16)23(26)30/h4-15H,1-3H3,(H2,26,30)(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173021
(4-{4-[4-(Chloro-difluoro-methoxy)-phenylamino]-pht...)Show SMILES COC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12 Show InChI InChI=1S/C23H16ClF2N3O3/c1-31-22(30)15-8-6-14(7-9-15)20-18-4-2-3-5-19(18)21(29-28-20)27-16-10-12-17(13-11-16)32-23(24,25)26/h2-13H,1H3,(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173051
(4-(4-(3,4-dichlorophenylamino)phthalazin-1-yl)benz...)Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(Cl)c(Cl)c2)c2ccccc12 Show InChI InChI=1S/C21H14Cl2N4O/c22-17-10-9-14(11-18(17)23)25-21-16-4-2-1-3-15(16)19(26-27-21)12-5-7-13(8-6-12)20(24)28/h1-11H,(H2,24,28)(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 840 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173024
(4-(4-(4-(chlorodifluoromethoxy)phenylamino)phthala...)Show SMILES OCCNC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12 Show InChI InChI=1S/C24H19ClF2N4O3/c25-24(26,27)34-18-11-9-17(10-12-18)29-22-20-4-2-1-3-19(20)21(30-31-22)15-5-7-16(8-6-15)23(33)28-13-14-32/h1-12,32H,13-14H2,(H,28,33)(H,29,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173041
(3,5-dimethoxy-N-(1-(naphthalen-2-ylmethyl)piperidi...)Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Nc2cccc(Br)c2)c2ccccc12 Show InChI InChI=1S/C21H15BrN4O/c22-15-4-3-5-16(12-15)24-21-18-7-2-1-6-17(18)19(25-26-21)13-8-10-14(11-9-13)20(23)27/h1-12H,(H2,23,27)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173011
(4-(4-(4-chlorophenylamino)phthalazin-1-yl)benzamid...)Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(Cl)cc2)c2ccccc12 Show InChI InChI=1S/C21H15ClN4O/c22-15-9-11-16(12-10-15)24-21-18-4-2-1-3-17(18)19(25-26-21)13-5-7-14(8-6-13)20(23)27/h1-12H,(H2,23,27)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173029
(4-(4-(m-tolylamino)phthalazin-1-yl)benzamide | 4-(...)Show SMILES Cc1cccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)c1 Show InChI InChI=1S/C22H18N4O/c1-14-5-4-6-17(13-14)24-22-19-8-3-2-7-18(19)20(25-26-22)15-9-11-16(12-10-15)21(23)27/h2-13H,1H3,(H2,23,27)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173012
(4-(4-(3-chlorophenylamino)phthalazin-1-yl)benzamid...)Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Nc2cccc(Cl)c2)c2ccccc12 Show InChI InChI=1S/C21H15ClN4O/c22-15-4-3-5-16(12-15)24-21-18-7-2-1-6-17(18)19(25-26-21)13-8-10-14(11-9-13)20(23)27/h1-12H,(H2,23,27)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173017
(4-(4-(p-tolylamino)phthalazin-1-yl)benzamide | 4-(...)Show SMILES Cc1ccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)cc1 Show InChI InChI=1S/C22H18N4O/c1-14-6-12-17(13-7-14)24-22-19-5-3-2-4-18(19)20(25-26-22)15-8-10-16(11-9-15)21(23)27/h2-13H,1H3,(H2,23,27)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173043
(4-(4-(4-methoxyphenylamino)phthalazin-1-yl)benzami...)Show SMILES COc1ccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)cc1 Show InChI InChI=1S/C22H18N4O2/c1-28-17-12-10-16(11-13-17)24-22-19-5-3-2-4-18(19)20(25-26-22)14-6-8-15(9-7-14)21(23)27/h2-13H,1H3,(H2,23,27)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173025
(4-[4-(4-Carbamoyl-phenyl)-phthalazin-1-ylamino]-be...)Show SMILES COC(=O)c1ccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)cc1 Show InChI InChI=1S/C23H18N4O3/c1-30-23(29)16-10-12-17(13-11-16)25-22-19-5-3-2-4-18(19)20(26-27-22)14-6-8-15(9-7-14)21(24)28/h2-13H,1H3,(H2,24,28)(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173013
(4-(4-(4-chlorophenylamino)phthalazin-1-yl)-N-methy...)Show SMILES CNC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(Cl)cc2)c2ccccc12 Show InChI InChI=1S/C22H17ClN4O/c1-24-22(28)15-8-6-14(7-9-15)20-18-4-2-3-5-19(18)21(27-26-20)25-17-12-10-16(23)11-13-17/h2-13H,1H3,(H,24,28)(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173047
(3-(4-(4-(chlorodifluoromethoxy)phenylamino)phthala...)Show SMILES NC(=O)c1cccc(c1)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12 Show InChI InChI=1S/C22H15ClF2N4O2/c23-22(24,25)31-16-10-8-15(9-11-16)27-21-18-7-2-1-6-17(18)19(28-29-21)13-4-3-5-14(12-13)20(26)30/h1-12H,(H2,26,30)(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173020
((4-(4-(4-(chlorodifluoromethoxy)phenylamino)phthal...)Show SMILES FC(F)(Cl)Oc1ccc(Nc2nnc(-c3ccc(cc3)C(=O)N3CCOCC3)c3ccccc23)cc1 Show InChI InChI=1S/C26H21ClF2N4O3/c27-26(28,29)36-20-11-9-19(10-12-20)30-24-22-4-2-1-3-21(22)23(31-32-24)17-5-7-18(8-6-17)25(34)33-13-15-35-16-14-33/h1-12H,13-16H2,(H,30,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173040
(4-[4-(2,4-Dimethyl-phenylamino)-phthalazin-1-yl]-b...)Show SMILES Cc1ccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)c(C)c1 Show InChI InChI=1S/C23H20N4O/c1-14-7-12-20(15(2)13-14)25-23-19-6-4-3-5-18(19)21(26-27-23)16-8-10-17(11-9-16)22(24)28/h3-13H,1-2H3,(H2,24,28)(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173014
(CHEMBL364974 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES Cc1ccc(cc1)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12 Show InChI InChI=1S/C22H16ClF2N3O/c1-14-6-8-15(9-7-14)20-18-4-2-3-5-19(18)21(28-27-20)26-16-10-12-17(13-11-16)29-22(23,24)25/h2-13H,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173028
(4-(4-(4-(benzyloxy)phenylamino)phthalazin-1-yl)ben...)Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(OCc3ccccc3)cc2)c2ccccc12 Show InChI InChI=1S/C28H22N4O2/c29-27(33)21-12-10-20(11-13-21)26-24-8-4-5-9-25(24)28(32-31-26)30-22-14-16-23(17-15-22)34-18-19-6-2-1-3-7-19/h1-17H,18H2,(H2,29,33)(H,30,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173035
((4-Chloro-phenyl)-[4-(4-ethoxy-phenyl)-phthalazin-...)Show SMILES CCOc1ccc(cc1)-c1nnc(Nc2ccc(Cl)cc2)c2ccccc12 Show InChI InChI=1S/C22H18ClN3O/c1-2-27-18-13-7-15(8-14-18)21-19-5-3-4-6-20(19)22(26-25-21)24-17-11-9-16(23)10-12-17/h3-14H,2H2,1H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173008
(4-(4-(4-(trifluoromethoxy)phenoxy)phthalazin-1-yl)...)Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Oc2ccc(OC(F)(F)F)cc2)c2ccccc12 Show InChI InChI=1S/C22H14F3N3O3/c23-22(24,25)31-16-11-9-15(10-12-16)30-21-18-4-2-1-3-17(18)19(27-28-21)13-5-7-14(8-6-13)20(26)29/h1-12H,(H2,26,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173023
((4-Methoxy-phenyl)-(4-phenyl-phthalazin-1-yl)-amin...)Show InChI InChI=1S/C21H17N3O/c1-25-17-13-11-16(12-14-17)22-21-19-10-6-5-9-18(19)20(23-24-21)15-7-3-2-4-8-15/h2-14H,1H3,(H,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173009
(4-(4-(4-(chlorodifluoromethoxy)phenylamino)phthala...)Show SMILES CC(C)NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12 Show InChI InChI=1S/C25H21ClF2N4O2/c1-15(2)29-24(33)17-9-7-16(8-10-17)22-20-5-3-4-6-21(20)23(32-31-22)30-18-11-13-19(14-12-18)34-25(26,27)28/h3-15H,1-2H3,(H,29,33)(H,30,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173044
(CHEMBL194138 | [4-(Chloro-difluoro-methoxy)-phenyl...)Show SMILES FC(F)(Cl)Oc1ccc(Nc2nnc(-c3ccc(Cl)cc3)c3ccccc23)cc1 Show InChI InChI=1S/C21H13Cl2F2N3O/c22-14-7-5-13(6-8-14)19-17-3-1-2-4-18(17)20(28-27-19)26-15-9-11-16(12-10-15)29-21(23,24)25/h1-12H,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173030
(4-[4-(4-Sulfamoyl-phenylamino)-phthalazin-1-yl]-be...)Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(cc2)S(N)(=O)=O)c2ccccc12 Show InChI InChI=1S/C21H17N5O3S/c22-20(27)14-7-5-13(6-8-14)19-17-3-1-2-4-18(17)21(26-25-19)24-15-9-11-16(12-10-15)30(23,28)29/h1-12H,(H2,22,27)(H,24,26)(H2,23,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173032
(4-[4-(4-Morpholin-4-yl-phenylamino)-phthalazin-1-y...)Show InChI InChI=1S/C19H18N4O2/c20-18(24)14-7-5-13(6-8-14)17-15-3-1-2-4-16(15)19(22-21-17)23-9-11-25-12-10-23/h1-8H,9-12H2,(H2,20,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173026
(CHEMBL370206 | [4-(4-Ethoxy-phenyl)-phthalazin-1-y...)Show InChI InChI=1S/C23H21N3O/c1-3-27-19-14-10-17(11-15-19)22-20-6-4-5-7-21(20)23(26-25-22)24-18-12-8-16(2)9-13-18/h4-15H,3H2,1-2H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173010
((4-Chloro-phenyl)-[4-(4-methoxy-phenyl)-phthalazin...)Show InChI InChI=1S/C21H16ClN3O/c1-26-17-12-6-14(7-13-17)20-18-4-2-3-5-19(18)21(25-24-20)23-16-10-8-15(22)9-11-16/h2-13H,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173050
(4-(4-(4-(trifluoromethoxy)phenylthio)phthalazin-1-...)Show SMILES NC(=O)c1ccc(cc1)-c1nnc(Sc2ccc(OC(F)(F)F)cc2)c2ccccc12 Show InChI InChI=1S/C22H14F3N3O2S/c23-22(24,25)30-15-9-11-16(12-10-15)31-21-18-4-2-1-3-17(18)19(27-28-21)13-5-7-14(8-6-13)20(26)29/h1-12H,(H2,26,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173048
(5-{4-[4-(Chloro-difluoro-methoxy)-phenylamino]-pht...)Show SMILES CC(C)NS(=O)(=O)c1cc(ccc1C)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12 Show InChI InChI=1S/C25H23ClF2N4O3S/c1-15(2)32-36(33,34)22-14-17(9-8-16(22)3)23-20-6-4-5-7-21(20)24(31-30-23)29-18-10-12-19(13-11-18)35-25(26,27)28/h4-15,32H,1-3H3,(H,29,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173042
(4-(4-(4-carbamoylphenyl)phthalazin-1-ylamino)benza...)Show SMILES NC(=O)c1ccc(Nc2nnc(-c3ccc(cc3)C(N)=O)c3ccccc23)cc1 Show InChI InChI=1S/C22H17N5O2/c23-20(28)14-7-5-13(6-8-14)19-17-3-1-2-4-18(17)22(27-26-19)25-16-11-9-15(10-12-16)21(24)29/h1-12H,(H2,23,28)(H2,24,29)(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173046
(CHEMBL196657 | [4-(4-Ethoxy-phenyl)-phthalazin-1-y...)Show SMILES CCOc1ccc(cc1)-c1nnc(Nc2ccc(OC)cc2)c2ccccc12 Show InChI InChI=1S/C23H21N3O2/c1-3-28-19-12-8-16(9-13-19)22-20-6-4-5-7-21(20)23(26-25-22)24-17-10-14-18(27-2)15-11-17/h4-15H,3H2,1-2H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173036
(4-[4-(4-Pyridin-1-yl-phenylamino)-phthalazin-1-yl]...)Show InChI InChI=1S/C20H20N4O/c21-19(25)15-10-8-14(9-11-15)18-16-6-2-3-7-17(16)20(23-22-18)24-12-4-1-5-13-24/h2-3,6-11H,1,4-5,12-13H2,(H2,21,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
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CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173027
(CHEMBL196940 | N,N-Dimethyl-4-(4-p-tolylamino-phth...)Show SMILES CN(C)C(=O)c1ccc(cc1)-c1nnc(Nc2ccc(C)cc2)c2ccccc12 Show InChI InChI=1S/C24H22N4O/c1-16-8-14-19(15-9-16)25-23-21-7-5-4-6-20(21)22(26-27-23)17-10-12-18(13-11-17)24(29)28(2)3/h4-15H,1-3H3,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173015
(CHEMBL196422 | N-tert-Butyl-4-{4-[4-(chloro-difluo...)Show SMILES CC(C)(C)NC(=O)c1ccc(cc1)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12 Show InChI InChI=1S/C26H23ClF2N4O2/c1-25(2,3)31-24(34)17-10-8-16(9-11-17)22-20-6-4-5-7-21(20)23(33-32-22)30-18-12-14-19(15-13-18)35-26(27,28)29/h4-15H,1-3H3,(H,30,33)(H,31,34) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173016
(4-(4-(phenylamino)phthalazin-1-yl)benzamide | 4-(4...)Show InChI InChI=1S/C21H16N4O/c22-20(26)15-12-10-14(11-13-15)19-17-8-4-5-9-18(17)21(25-24-19)23-16-6-2-1-3-7-16/h1-13H,(H2,22,26)(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173052
(5-{4-[4-(Chloro-difluoro-methoxy)-phenylamino]-pht...)Show SMILES Cc1ccc(cc1S(N)(=O)=O)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12 Show InChI InChI=1S/C22H17ClF2N4O3S/c1-13-6-7-14(12-19(13)33(26,30)31)20-17-4-2-3-5-18(17)21(29-28-20)27-15-8-10-16(11-9-15)32-22(23,24)25/h2-12H,1H3,(H,27,29)(H2,26,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173037
(CHEMBL195727 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES FC(F)(Cl)Oc1ccc(Nc2nnc(-c3ccccc3)c3ccccc23)cc1 Show InChI InChI=1S/C21H14ClF2N3O/c22-21(23,24)28-16-12-10-15(11-13-16)25-20-18-9-5-4-8-17(18)19(26-27-20)14-6-2-1-3-7-14/h1-13H,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173018
(CHEMBL195829 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES COc1ccc(cc1)-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)c2ccccc12 Show InChI InChI=1S/C22H16ClF2N3O2/c1-29-16-10-6-14(7-11-16)20-18-4-2-3-5-19(18)21(28-27-20)26-15-8-12-17(13-9-15)30-22(23,24)25/h2-13H,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173038
((3,4-Dichloro-phenyl)-(4-p-tolyl-phthalazin-1-yl)-...)Show SMILES Cc1ccc(cc1)-c1nnc(Nc2ccc(Cl)c(Cl)c2)c2ccccc12 Show InChI InChI=1S/C21H15Cl2N3/c1-13-6-8-14(9-7-13)20-16-4-2-3-5-17(16)21(26-25-20)24-15-10-11-18(22)19(23)12-15/h2-12H,1H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173039
((4-Chloro-phenyl)-(4-p-tolyl-phthalazin-1-yl)-amin...)Show InChI InChI=1S/C21H16ClN3/c1-14-6-8-15(9-7-14)20-18-4-2-3-5-19(18)21(25-24-20)23-17-12-10-16(22)11-13-17/h2-13H,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50173033
((3,4-Dichloro-phenyl)-[4-(4-methoxy-phenyl)-phthal...)Show SMILES COc1ccc(cc1)-c1nnc(Nc2ccc(Cl)c(Cl)c2)c2ccccc12 Show InChI InChI=1S/C21H15Cl2N3O/c1-27-15-9-6-13(7-10-15)20-16-4-2-3-5-17(16)21(26-25-20)24-14-8-11-18(22)19(23)12-14/h2-12H,1H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ImClone Systems
Curated by ChEMBL
| Assay Description
Inhibition of Vascular endothelial growth factor receptor 2 kinase phosphorylation of pGAT-biotin peptide |
Bioorg Med Chem Lett 15: 4696-8 (2005)
Article DOI: 10.1016/j.bmcl.2005.07.064
BindingDB Entry DOI: 10.7270/Q25Q4VNS |
More data for this
Ligand-Target Pair | |
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