Found 28 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM13530
(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34) | PDB
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| Article
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| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174413
(2-(2-Diethylamino-ethyl)-9-hydroxy-5,11-dimethyl-6...)Show SMILES CCN(CC)CCn1ccc2c(C)c3[nH+]c4ccc(O)cc4c3c(C)c2c1 Show InChI InChI=1S/C23H27N3O/c1-5-25(6-2)11-12-26-10-9-18-16(4)23-22(15(3)20(18)14-26)19-13-17(27)7-8-21(19)24-23/h7-10,13-14,27H,5-6,11-12H2,1-4H3/p+1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50004227
(5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...)Show InChI InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3 | PDB
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| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 3
(Homo sapiens (Human)) | BDBM50004227
(5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...)Show InChI InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
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| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory activity against Fibroblast growth factor receptor 3 |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50004227
(5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...)Show InChI InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3 | PDB
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| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50004235
((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1 | PDB
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| CHEMBL
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| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50004235
((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1 | PDB
UniProtKB/SwissProt
antibodypedia
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| CHEMBL
PC cid
PC sid
UniChem
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| Article
PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174413
(2-(2-Diethylamino-ethyl)-9-hydroxy-5,11-dimethyl-6...)Show SMILES CCN(CC)CCn1ccc2c(C)c3[nH+]c4ccc(O)cc4c3c(C)c2c1 Show InChI InChI=1S/C23H27N3O/c1-5-25(6-2)11-12-26-10-9-18-16(4)23-22(15(3)20(18)14-26)19-13-17(27)7-8-21(19)24-23/h7-10,13-14,27H,5-6,11-12H2,1-4H3/p+1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
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PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 3
(Homo sapiens (Human)) | BDBM50004235
((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory activity against Fibroblast growth factor receptor 3 |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50004227
(5,11-Dimethyl-6H-pyrido[4,3-b]carbazol-9-ol | 5,11...)Show InChI InChI=1S/C17H14N2O/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17/h3-8,19-20H,1-2H3 | PDB
KEGG
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CHEMBL
MCE
PC cid
PC sid
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PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory activity against Platelet-derived growth factor receptor alpha |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB
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CHEMBL
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| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50004235
((NMHE)9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]c...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-20(3)7-6-13(15)11(2)18-17(10)14-8-12(21)4-5-16(14)19-18/h4-9,21H,1-3H3/p+1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank
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GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory activity against Platelet-derived growth factor receptor alpha |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174412
(9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole ...)Show InChI InChI=1S/C18H16N2O/c1-10-15-9-19-7-6-13(15)11(2)18-17(10)14-8-12(21-3)4-5-16(14)20-18/h4-9,20H,1-3H3 | PDB
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CHEMBL
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| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174410
(1-(3-Diethylamino-propylamino)-5,11-dimethyl-6H-py...)Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ccc(O)cc4c3c(C)c12 Show InChI InChI=1S/C24H30N4O/c1-5-28(6-2)13-7-11-25-24-22-16(4)21-19-14-17(29)8-9-20(19)27-23(21)15(3)18(22)10-12-26-24/h8-10,12,14,27,29H,5-7,11,13H2,1-4H3,(H,25,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174410
(1-(3-Diethylamino-propylamino)-5,11-dimethyl-6H-py...)Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ccc(O)cc4c3c(C)c12 Show InChI InChI=1S/C24H30N4O/c1-5-28(6-2)13-7-11-25-24-22-16(4)21-19-14-17(29)8-9-20(19)27-23(21)15(3)18(22)10-12-26-24/h8-10,12,14,27,29H,5-7,11,13H2,1-4H3,(H,25,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 3
(Homo sapiens (Human)) | BDBM50174408
(1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...)Show SMILES CCN(CC)CCCNc1nccc2c(C)c3n(C)c4ccc(O)cc4c3c(C)c12 Show InChI InChI=1S/C25H32N4O/c1-6-29(7-2)14-8-12-26-25-23-17(4)22-20-15-18(30)9-10-21(20)28(5)24(22)16(3)19(23)11-13-27-25/h9-11,13,15,30H,6-8,12,14H2,1-5H3,(H,26,27) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory activity against Fibroblast growth factor receptor 3 |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174411
(CHEMBL197610 | N,N-Diethyl-N'-(10-methyl-11H-pyrid...)Show InChI InChI=1S/C22H27N5/c1-4-27(5-2)13-7-11-23-21-19-14-18-17-8-6-10-24-22(17)26-20(18)15(3)16(19)9-12-25-21/h6,8-10,12,14H,4-5,7,11,13H2,1-3H3,(H,23,25)(H,24,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174407
(CHEMBL279472 | N,N-Diethyl-N'-(9-methoxy-5-methyl-...)Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ccc(OC)cc4c3cc12 Show InChI InChI=1S/C24H30N4O/c1-5-28(6-2)13-7-11-25-24-21-15-20-19-14-17(29-4)8-9-22(19)27-23(20)16(3)18(21)10-12-26-24/h8-10,12,14-15,27H,5-7,11,13H2,1-4H3,(H,25,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50174408
(1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...)Show SMILES CCN(CC)CCCNc1nccc2c(C)c3n(C)c4ccc(O)cc4c3c(C)c12 Show InChI InChI=1S/C25H32N4O/c1-6-29(7-2)14-8-12-26-25-23-17(4)22-20-15-18(30)9-10-21(20)28(5)24(22)16(3)19(23)11-13-27-25/h9-11,13,15,30H,6-8,12,14H2,1-5H3,(H,26,27) | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory activity against Platelet-derived growth factor receptor alpha |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174411
(CHEMBL197610 | N,N-Diethyl-N'-(10-methyl-11H-pyrid...)Show InChI InChI=1S/C22H27N5/c1-4-27(5-2)13-7-11-23-21-19-14-18-17-8-6-10-24-22(17)26-20(18)15(3)16(19)9-12-25-21/h6,8-10,12,14H,4-5,7,11,13H2,1-3H3,(H,23,25)(H,24,26) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174408
(1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...)Show SMILES CCN(CC)CCCNc1nccc2c(C)c3n(C)c4ccc(O)cc4c3c(C)c12 Show InChI InChI=1S/C25H32N4O/c1-6-29(7-2)14-8-12-26-25-23-17(4)22-20-15-18(30)9-10-21(20)28(5)24(22)16(3)19(23)11-13-27-25/h9-11,13,15,30H,6-8,12,14H2,1-5H3,(H,26,27) | PDB
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| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174407
(CHEMBL279472 | N,N-Diethyl-N'-(9-methoxy-5-methyl-...)Show SMILES CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ccc(OC)cc4c3cc12 Show InChI InChI=1S/C24H30N4O/c1-5-28(6-2)13-7-11-25-24-21-15-20-19-14-17(29-4)8-9-22(19)27-23(20)16(3)18(21)10-12-26-24/h8-10,12,14-15,27H,5-7,11,13H2,1-4H3,(H,25,26) | PDB
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antibodypedia
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| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174408
(1-(3-Diethylamino-propylamino)-5,6,11-trimethyl-6H...)Show SMILES CCN(CC)CCCNc1nccc2c(C)c3n(C)c4ccc(O)cc4c3c(C)c12 Show InChI InChI=1S/C25H32N4O/c1-6-29(7-2)14-8-12-26-25-23-17(4)22-20-15-18(30)9-10-21(20)28(5)24(22)16(3)19(23)11-13-27-25/h9-11,13,15,30H,6-8,12,14H2,1-5H3,(H,26,27) | PDB
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| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174409
(9-Bromo-5,11-dimethyl-6H-pyrido[4,3-b]carbazole | ...)Show InChI InChI=1S/C17H13BrN2/c1-9-14-8-19-6-5-12(14)10(2)17-16(9)13-7-11(18)3-4-15(13)20-17/h3-8,20H,1-2H3 | PDB
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50004233
(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)Show InChI InChI=1S/C17H14N2/c1-10-14-9-18-8-7-12(14)11(2)17-16(10)13-5-3-4-6-15(13)19-17/h3-9,19H,1-2H3 | PDB
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MCE
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MMDB
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50174409
(9-Bromo-5,11-dimethyl-6H-pyrido[4,3-b]carbazole | ...)Show InChI InChI=1S/C17H13BrN2/c1-9-14-8-19-6-5-12(14)10(2)17-16(9)13-7-11(18)3-4-15(13)20-17/h3-8,20H,1-2H3 | PDB
UniProtKB/SwissProt
antibodypedia
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PC cid
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UniChem
| Article
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50004233
(5,11-dimethyl-2H-pyrido[4,3-b]carbazole | CHEMBL12...)Show InChI InChI=1S/C17H14N2/c1-10-14-9-18-8-7-12(14)11(2)17-16(10)13-5-3-4-6-15(13)19-17/h3-9,19H,1-2H3 | PDB
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| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit wild type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM13530
(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34) | PDB
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| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS UMR-8113
Curated by ChEMBL
| Assay Description
Inhibitory concentration against c-Kit D816V type expressed in recombinant baculovirus |
J Med Chem 48: 6194-201 (2005)
Article DOI: 10.1021/jm050231m
BindingDB Entry DOI: 10.7270/Q2B27TTR |
More data for this
Ligand-Target Pair | |
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