Found 8 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Carbonic anhydrase 2
(Bos taurus) | BDBM50175052
((2E)-(4-benzoyloxy)but-2-enyl-4-(aminosulfonyl)ben...)Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)OC\C=C\COC(=O)c1ccccc1 Show InChI InChI=1S/C18H17NO6S/c19-26(22,23)16-10-8-15(9-11-16)18(21)25-13-5-4-12-24-17(20)14-6-2-1-3-7-14/h1-11H,12-13H2,(H2,19,22,23)/b5-4+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Displacement of DNSA from CAII in bovine erythrocytes |
Bioorg Med Chem Lett 15: 5429-33 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.113
BindingDB Entry DOI: 10.7270/Q2TX3DZ1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Bos taurus) | BDBM50175053
((2E)-but-2-en-1,4-diyl-bis[(aminosulfonyl)benzoate...)Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)OC\C=C\COC(=O)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18N2O8S2/c19-29(23,24)15-7-3-13(4-8-15)17(21)27-11-1-2-12-28-18(22)14-5-9-16(10-6-14)30(20,25)26/h1-10H,11-12H2,(H2,19,23,24)(H2,20,25,26)/b2-1+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Displacement of DNSA from CAII in bovine erythrocytes |
Bioorg Med Chem Lett 15: 5429-33 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.113
BindingDB Entry DOI: 10.7270/Q2TX3DZ1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Bos taurus) | BDBM50175054
((2E)-4-hydroxybut-2-enyl-4-(aminosulfonyl)benzoate...)Show InChI InChI=1S/C11H13NO5S/c12-18(15,16)10-5-3-9(4-6-10)11(14)17-8-2-1-7-13/h1-6,13H,7-8H2,(H2,12,15,16)/b2-1+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Displacement of DNSA from CAII in bovine erythrocytes |
Bioorg Med Chem Lett 15: 5429-33 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.113
BindingDB Entry DOI: 10.7270/Q2TX3DZ1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Bos taurus) | BDBM50175055
(1-pentenyl-4-(aminosulfonyl)benzoate | CHEMBL20007...)Show InChI InChI=1S/C12H15NO4S/c1-2-3-4-9-17-12(14)10-5-7-11(8-6-10)18(13,15)16/h2,5-8H,1,3-4,9H2,(H2,13,15,16) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Displacement of DNSA from CAII in bovine erythrocytes |
Bioorg Med Chem Lett 15: 5429-33 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.113
BindingDB Entry DOI: 10.7270/Q2TX3DZ1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Bos taurus) | BDBM50175049
(CHEMBL381455 | allyl 4-(aminosulfonyl)benzoate)Show InChI InChI=1S/C10H11NO4S/c1-2-7-15-10(12)8-3-5-9(6-4-8)16(11,13)14/h2-6H,1,7H2,(H2,11,13,14) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Displacement of DNSA from CAII in bovine erythrocytes |
Bioorg Med Chem Lett 15: 5429-33 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.113
BindingDB Entry DOI: 10.7270/Q2TX3DZ1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Bos taurus) | BDBM50175051
((2Z)-4-hydroxybut-2-enyl-4-(aminosulfonyl)benzoate...)Show InChI InChI=1S/C11H13NO5S/c12-18(15,16)10-5-3-9(4-6-10)11(14)17-8-2-1-7-13/h1-6,13H,7-8H2,(H2,12,15,16)/b2-1- | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Displacement of DNSA from CAII in bovine erythrocytes |
Bioorg Med Chem Lett 15: 5429-33 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.113
BindingDB Entry DOI: 10.7270/Q2TX3DZ1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Bos taurus) | BDBM50175050
((2Z)-but-2-en-1,4-diyl-bis[(aminosulfonyl)benzoate...)Show SMILES NS(=O)(=O)c1ccc(cc1)C(=O)OC\C=C/COC(=O)c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H18N2O8S2/c19-29(23,24)15-7-3-13(4-8-15)17(21)27-11-1-2-12-28-18(22)14-5-9-16(10-6-14)30(20,25)26/h1-10H,11-12H2,(H2,19,23,24)(H2,20,25,26)/b2-1- | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Displacement of DNSA from CAII in bovine erythrocytes |
Bioorg Med Chem Lett 15: 5429-33 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.113
BindingDB Entry DOI: 10.7270/Q2TX3DZ1 |
More data for this
Ligand-Target Pair | |
Carbonic anhydrase 2
(Bos taurus) | BDBM4703
(4-carboxybenzenesulfonamide 1 | 4-sulfamoylbenzoic...)Show InChI InChI=1S/C7H7NO4S/c8-13(11,12)6-3-1-5(2-4-6)7(9)10/h1-4H,(H,9,10)(H2,8,11,12) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 151 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Griffith University
Curated by ChEMBL
| Assay Description
Displacement of DNSA from CAII in bovine erythrocytes |
Bioorg Med Chem Lett 15: 5429-33 (2005)
Article DOI: 10.1016/j.bmcl.2005.08.113
BindingDB Entry DOI: 10.7270/Q2TX3DZ1 |
More data for this
Ligand-Target Pair | |
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