Affinity Data by PubMed id=16216042

PubMed code 16216042

Found 10 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM84573 (VS-83) Show SMILES Oc1cccc(c1)C1NC(=S)Nc2cccc(F)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a	6.8	25
University of Leipzig					Assay Description The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.				Chembiochem 6: 2005-13 (2005) Article DOI: 10.1002/cbic.200500168 BindingDB Entry DOI: 10.7270/Q2XW4HB5
University of Leipzig					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM84575 (VS-54) Show SMILES Oc1cccc(c1)C1NC(=S)Nc2cc(F)ccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	6.8	25
University of Leipzig					Assay Description The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.				Chembiochem 6: 2005-13 (2005) Article DOI: 10.1002/cbic.200500168 BindingDB Entry DOI: 10.7270/Q2XW4HB5
University of Leipzig					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM84577 (VS-94) Show SMILES Cc1ccc2NC(=S)NC(c3cccc(O)c3)c2c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.73E+3	n/a	n/a	n/a	n/a	6.8	25
University of Leipzig					Assay Description The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.				Chembiochem 6: 2005-13 (2005) Article DOI: 10.1002/cbic.200500168 BindingDB Entry DOI: 10.7270/Q2XW4HB5
University of Leipzig					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM84576 (VS-87) Show SMILES Oc1cccc(c1)C1NC(=S)Nc2cc(F)c(F)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.74E+3	n/a	n/a	n/a	n/a	6.8	25
University of Leipzig					Assay Description The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.				Chembiochem 6: 2005-13 (2005) Article DOI: 10.1002/cbic.200500168 BindingDB Entry DOI: 10.7270/Q2XW4HB5
University of Leipzig					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM84578 (VS-17) Show SMILES Oc1cccc(c1)C1NC(=S)Nc2ccc(Br)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.75E+3	n/a	n/a	n/a	n/a	6.8	25
University of Leipzig					Assay Description The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.				Chembiochem 6: 2005-13 (2005) Article DOI: 10.1002/cbic.200500168 BindingDB Entry DOI: 10.7270/Q2XW4HB5
University of Leipzig					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM84572 (VS-42) Show SMILES Oc1cccc(c1)C1NC(=S)Nc2ccc(Cl)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.77E+3	n/a	n/a	n/a	n/a	6.8	25
University of Leipzig					Assay Description The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.				Chembiochem 6: 2005-13 (2005) Article DOI: 10.1002/cbic.200500168 BindingDB Entry DOI: 10.7270/Q2XW4HB5
University of Leipzig					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM84580 (VS-91) Show SMILES Cc1ccc2C(NC(=S)Nc2c1)c1cccc(O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.59E+3	n/a	n/a	n/a	n/a	6.8	25
University of Leipzig					Assay Description The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.				Chembiochem 6: 2005-13 (2005) Article DOI: 10.1002/cbic.200500168 BindingDB Entry DOI: 10.7270/Q2XW4HB5
University of Leipzig					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM84574 (VS-12) Show SMILES Oc1cccc(c1)C1NC(=S)Nc2ccccc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	6.8	25
University of Leipzig					Assay Description The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.				Chembiochem 6: 2005-13 (2005) Article DOI: 10.1002/cbic.200500168 BindingDB Entry DOI: 10.7270/Q2XW4HB5
University of Leipzig					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM84579 (VS-77) Show SMILES Oc1cccc(c1)C1NC(=S)Nc2ccc(F)cc12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.04E+3	n/a	n/a	n/a	n/a	6.8	25
University of Leipzig					Assay Description The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.				Chembiochem 6: 2005-13 (2005) Article DOI: 10.1002/cbic.200500168 BindingDB Entry DOI: 10.7270/Q2XW4HB5
University of Leipzig					More data for this Ligand-Target Pair
Kinesin-like protein KIF11 (Homo sapiens (Human))	BDBM50198309 ((S)-4-(3-Hydroxy-phenyl)-6-methyl-2-thioxo-1,2,3,4...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	2.07E+4	n/a	n/a	n/a	n/a	6.8	25
University of Leipzig					Assay Description The ATPase activity of the Eg5 motor domain was measured by using the malachite green assay.				Chembiochem 6: 2005-13 (2005) Article DOI: 10.1002/cbic.200500168 BindingDB Entry DOI: 10.7270/Q2XW4HB5
University of Leipzig					More data for this Ligand-Target Pair				3D Structure (crystal)

* indicates data uncertainty>20%