Found 8 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50175259
((R)-N-(5-chloro-2-methylphenyl)-2-ethylpiperidine-...)Show InChI InChI=1S/C15H21ClN2S/c1-3-13-6-4-5-9-18(13)15(19)17-14-10-12(16)8-7-11(14)2/h7-8,10,13H,3-6,9H2,1-2H3,(H,17,19)/t13-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Activity against PPAR-delta |
Bioorg Med Chem Lett 16: 113-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.09.034
BindingDB Entry DOI: 10.7270/Q29023BW |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Rattus norvegicus) | BDBM50175261
(1-(5-chloro-2-methylphenyl)-3-isobutylthiourea | C...)Show InChI InChI=1S/C12H17ClN2S/c1-8(2)7-14-12(16)15-11-6-10(13)5-4-9(11)3/h4-6,8H,7H2,1-3H3,(H2,14,15,16) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Activity against PPAR-alpha |
Bioorg Med Chem Lett 16: 113-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.09.034
BindingDB Entry DOI: 10.7270/Q29023BW |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Rattus norvegicus) | BDBM50175259
((R)-N-(5-chloro-2-methylphenyl)-2-ethylpiperidine-...)Show InChI InChI=1S/C15H21ClN2S/c1-3-13-6-4-5-9-18(13)15(19)17-14-10-12(16)8-7-11(14)2/h7-8,10,13H,3-6,9H2,1-2H3,(H,17,19)/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Activity against PPAR-alpha |
Bioorg Med Chem Lett 16: 113-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.09.034
BindingDB Entry DOI: 10.7270/Q29023BW |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50175262
((S)-N-(5-chloro-2-methylphenyl)-2-ethylpiperidine-...)Show InChI InChI=1S/C15H21ClN2S/c1-3-13-6-4-5-9-18(13)15(19)17-14-10-12(16)8-7-11(14)2/h7-8,10,13H,3-6,9H2,1-2H3,(H,17,19)/t13-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Activity against PPAR-delta |
Bioorg Med Chem Lett 16: 113-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.09.034
BindingDB Entry DOI: 10.7270/Q29023BW |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Rattus norvegicus) | BDBM50175262
((S)-N-(5-chloro-2-methylphenyl)-2-ethylpiperidine-...)Show InChI InChI=1S/C15H21ClN2S/c1-3-13-6-4-5-9-18(13)15(19)17-14-10-12(16)8-7-11(14)2/h7-8,10,13H,3-6,9H2,1-2H3,(H,17,19)/t13-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Activity against PPAR-alpha |
Bioorg Med Chem Lett 16: 113-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.09.034
BindingDB Entry DOI: 10.7270/Q29023BW |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50175261
(1-(5-chloro-2-methylphenyl)-3-isobutylthiourea | C...)Show InChI InChI=1S/C12H17ClN2S/c1-8(2)7-14-12(16)15-11-6-10(13)5-4-9(11)3/h4-6,8H,7H2,1-3H3,(H2,14,15,16) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Activity against PPAR-delta |
Bioorg Med Chem Lett 16: 113-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.09.034
BindingDB Entry DOI: 10.7270/Q29023BW |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50175260
(1-(5-chloro-2-methylphenyl)-3-propylthiourea | CHE...)Show InChI InChI=1S/C11H15ClN2S/c1-3-6-13-11(15)14-10-7-9(12)5-4-8(10)2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Activity against PPAR-delta |
Bioorg Med Chem Lett 16: 113-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.09.034
BindingDB Entry DOI: 10.7270/Q29023BW |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Rattus norvegicus) | BDBM50175260
(1-(5-chloro-2-methylphenyl)-3-propylthiourea | CHE...)Show InChI InChI=1S/C11H15ClN2S/c1-3-6-13-11(15)14-10-7-9(12)5-4-8(10)2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research
Curated by ChEMBL
| Assay Description
Activity against PPAR-alpha |
Bioorg Med Chem Lett 16: 113-7 (2005)
Article DOI: 10.1016/j.bmcl.2005.09.034
BindingDB Entry DOI: 10.7270/Q29023BW |
More data for this
Ligand-Target Pair | |
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