Affinity Data by PubMed id=16250640

PubMed code 16250640

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50176016 (2-[5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Antagonist activity against human Adenosine A2b receptor				J Med Chem 48: 6813-20 (2005) Article DOI: 10.1021/jm049418o BindingDB Entry DOI: 10.7270/Q2542N5D
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50176017 (8-(6-Hydroxy-pyridin-3-yl)-1,3-dipropyl-3,7-dihydr...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Antagonist activity against human Adenosine A2b receptor				J Med Chem 48: 6813-20 (2005) Article DOI: 10.1021/jm049418o BindingDB Entry DOI: 10.7270/Q2542N5D
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50229885 (CHEMBL260331 \| CHEMBL506685 \| N-(benzo[d][1,3]diox...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Antagonist activity against human Adenosine A2b receptor				J Med Chem 48: 6813-20 (2005) Article DOI: 10.1021/jm049418o BindingDB Entry DOI: 10.7270/Q2542N5D
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50021450 (8-(4-Amino-phenyl)-1,3-dipropyl-3,7-dihydro-purine...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Antagonist activity against human Adenosine A2b receptor				J Med Chem 48: 6813-20 (2005) Article DOI: 10.1021/jm049418o BindingDB Entry DOI: 10.7270/Q2542N5D
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50176015 (CHEMBL198326 \| [5-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Antagonist activity against human Adenosine A2b receptor				J Med Chem 48: 6813-20 (2005) Article DOI: 10.1021/jm049418o BindingDB Entry DOI: 10.7270/Q2542N5D
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM50018162 (4-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-pu...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Antagonist activity against human Adenosine A2b receptor				J Med Chem 48: 6813-20 (2005) Article DOI: 10.1021/jm049418o BindingDB Entry DOI: 10.7270/Q2542N5D
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A2b (Homo sapiens (Human))	BDBM10847 (1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dion...) Show SMILES Cn1c2nc[nH]c2c(=O)n(C)c1=O Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	9.07E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
M. V. Lomonosov Moscow State University Curated by ChEMBL					Assay Description Antagonist activity against human Adenosine A2b receptor				J Med Chem 48: 6813-20 (2005) Article DOI: 10.1021/jm049418o BindingDB Entry DOI: 10.7270/Q2542N5D
M. V. Lomonosov Moscow State University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%