Found 86 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM9504
(2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...)Show InChI InChI=1S/C22H18N4O/c27-22(26-18-13-17-5-1-3-7-20(17)25-15-18)19-6-2-4-8-21(19)24-14-16-9-11-23-12-10-16/h1-13,15,24H,14H2,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM21
(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)Show SMILES COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1 Show InChI InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178528
(CHEMBL205127 | N-(4-chloro-3-(trifluoromethyl)phen...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Cl)c(c2)C(F)(F)F)o1 Show InChI InChI=1S/C19H15ClF3N7O/c1-30-10-26-16(25-9-11-4-6-24-7-5-11)15(30)17-28-29-18(31-17)27-12-2-3-14(20)13(8-12)19(21,22)23/h2-8,10,25H,9H2,1H3,(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178509
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2cccc(OC(F)(F)F)c2)o1 Show InChI InChI=1S/C19H16F3N7O2/c1-29-11-25-16(24-10-12-5-7-23-8-6-12)15(29)17-27-28-18(30-17)26-13-3-2-4-14(9-13)31-19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM9504
(2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...)Show InChI InChI=1S/C22H18N4O/c27-22(26-18-13-17-5-1-3-7-20(17)25-15-18)19-6-2-4-8-21(19)24-14-16-9-11-23-12-10-16/h1-13,15,24H,14H2,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178519
(CHEMBL378592 | N-(3,4-dimethoxyphenyl)-5-(1-methyl...)Show SMILES COc1ccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)cc1OC Show InChI InChI=1S/C20H21N7O3/c1-27-12-23-18(22-11-13-6-8-21-9-7-13)17(27)19-25-26-20(30-19)24-14-4-5-15(28-2)16(10-14)29-3/h4-10,12,22H,11H2,1-3H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178511
(CHEMBL203796 | N-(3-methoxyphenyl)-5-(1-methyl-4-(...)Show SMILES COc1cccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)c1 Show InChI InChI=1S/C19H19N7O2/c1-26-12-22-17(21-11-13-6-8-20-9-7-13)16(26)18-24-25-19(28-18)23-14-4-3-5-15(10-14)27-2/h3-10,12,21H,11H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178524
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(OC(F)(F)F)cc2)o1 Show InChI InChI=1S/C19H16F3N7O2/c1-29-11-25-16(24-10-12-6-8-23-9-7-12)15(29)17-27-28-18(30-17)26-13-2-4-14(5-3-13)31-19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178526
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(cc2)C(F)(F)F)o1 Show InChI InChI=1S/C19H16F3N7O/c1-29-11-25-16(24-10-12-6-8-23-9-7-12)15(29)17-27-28-18(30-17)26-14-4-2-13(3-5-14)19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178526
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(cc2)C(F)(F)F)o1 Show InChI InChI=1S/C19H16F3N7O/c1-29-11-25-16(24-10-12-6-8-23-9-7-12)15(29)17-27-28-18(30-17)26-14-4-2-13(3-5-14)19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Similars
| PDB
Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178524
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(OC(F)(F)F)cc2)o1 Show InChI InChI=1S/C19H16F3N7O2/c1-29-11-25-16(24-10-12-6-8-23-9-7-12)15(29)17-27-28-18(30-17)26-13-2-4-14(5-3-13)31-19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178519
(CHEMBL378592 | N-(3,4-dimethoxyphenyl)-5-(1-methyl...)Show SMILES COc1ccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)cc1OC Show InChI InChI=1S/C20H21N7O3/c1-27-12-23-18(22-11-13-6-8-21-9-7-13)17(27)19-25-26-20(30-19)24-14-4-5-15(28-2)16(10-14)29-3/h4-10,12,22H,11H2,1-3H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178529
(CHEMBL205884 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)o1 Show InChI InChI=1S/C19H16ClF2N7O2/c1-29-11-25-16(24-10-12-6-8-23-9-7-12)15(29)17-27-28-18(30-17)26-13-2-4-14(5-3-13)31-19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 96 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM21
(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)Show SMILES COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1 Show InChI InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178528
(CHEMBL205127 | N-(4-chloro-3-(trifluoromethyl)phen...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Cl)c(c2)C(F)(F)F)o1 Show InChI InChI=1S/C19H15ClF3N7O/c1-30-10-26-16(25-9-11-4-6-24-7-5-11)15(30)17-28-29-18(31-17)27-12-2-3-14(20)13(8-12)19(21,22)23/h2-8,10,25H,9H2,1H3,(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178526
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(cc2)C(F)(F)F)o1 Show InChI InChI=1S/C19H16F3N7O/c1-29-11-25-16(24-10-12-6-8-23-9-7-12)15(29)17-27-28-18(30-17)26-14-4-2-13(3-5-14)19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178511
(CHEMBL203796 | N-(3-methoxyphenyl)-5-(1-methyl-4-(...)Show SMILES COc1cccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)c1 Show InChI InChI=1S/C19H19N7O2/c1-26-12-22-17(21-11-13-6-8-20-9-7-13)16(26)18-24-25-19(28-18)23-14-4-3-5-15(10-14)27-2/h3-10,12,21H,11H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178509
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2cccc(OC(F)(F)F)c2)o1 Show InChI InChI=1S/C19H16F3N7O2/c1-29-11-25-16(24-10-12-5-7-23-8-6-12)15(29)17-27-28-18(30-17)26-13-3-2-4-14(9-13)31-19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178529
(CHEMBL205884 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)o1 Show InChI InChI=1S/C19H16ClF2N7O2/c1-29-11-25-16(24-10-12-6-8-23-9-7-12)15(29)17-27-28-18(30-17)26-13-2-4-14(5-3-13)31-19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM4851
((4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-...)Show InChI InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178520
(CHEMBL202892 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(NCc2ccc3OCOc3c2)o1 Show InChI InChI=1S/C20H19N7O3/c1-27-11-24-18(22-9-13-4-6-21-7-5-13)17(27)19-25-26-20(30-19)23-10-14-2-3-15-16(8-14)29-12-28-15/h2-8,11,22H,9-10,12H2,1H3,(H,23,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM9504
(2-[(pyridin-4-ylmethyl)amino]-N-(quinolin-3-yl)ben...)Show InChI InChI=1S/C22H18N4O/c27-22(26-18-13-17-5-1-3-7-20(17)25-15-18)19-6-2-4-8-21(19)24-14-16-9-11-23-12-10-16/h1-13,15,24H,14H2,(H,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178524
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(OC(F)(F)F)cc2)o1 Show InChI InChI=1S/C19H16F3N7O2/c1-29-11-25-16(24-10-12-6-8-23-9-7-12)15(29)17-27-28-18(30-17)26-13-2-4-14(5-3-13)31-19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM9503
(2-[(pyridin-4-ylmethyl)amino]-N-[3-(trifluoromethy...)Show InChI InChI=1S/C20H16F3N3O/c21-20(22,23)15-4-3-5-16(12-15)26-19(27)17-6-1-2-7-18(17)25-13-14-8-10-24-11-9-14/h1-12,25H,13H2,(H,26,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178523
(CHEMBL204874 | N-(3,4-dichlorophenyl)-5-(1-methyl-...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Cl)c(Cl)c2)o1 Show InChI InChI=1S/C18H15Cl2N7O/c1-27-10-23-16(22-9-11-4-6-21-7-5-11)15(27)17-25-26-18(28-17)24-12-2-3-13(19)14(20)8-12/h2-8,10,22H,9H2,1H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178513
(CHEMBL203056 | N-(4-chlorophenyl)-5-(1-methyl-4-(p...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C18H16ClN7O/c1-26-11-22-16(21-10-12-6-8-20-9-7-12)15(26)17-24-25-18(27-17)23-14-4-2-13(19)3-5-14/h2-9,11,21H,10H2,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 250 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178523
(CHEMBL204874 | N-(3,4-dichlorophenyl)-5-(1-methyl-...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Cl)c(Cl)c2)o1 Show InChI InChI=1S/C18H15Cl2N7O/c1-27-10-23-16(22-9-11-4-6-21-7-5-11)15(27)17-25-26-18(28-17)24-12-2-3-13(19)14(20)8-12/h2-8,10,22H,9H2,1H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178521
(CHEMBL379908 | N-(2-fluoro-4-methylphenyl)-5-(1-me...)Show SMILES Cc1ccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)c(F)c1 Show InChI InChI=1S/C19H18FN7O/c1-12-3-4-15(14(20)9-12)24-19-26-25-18(28-19)16-17(23-11-27(16)2)22-10-13-5-7-21-8-6-13/h3-9,11,22H,10H2,1-2H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178520
(CHEMBL202892 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(NCc2ccc3OCOc3c2)o1 Show InChI InChI=1S/C20H19N7O3/c1-27-11-24-18(22-9-13-4-6-21-7-5-13)17(27)19-25-26-20(30-19)23-10-14-2-3-15-16(8-14)29-12-28-15/h2-8,11,22H,9-10,12H2,1H3,(H,23,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178513
(CHEMBL203056 | N-(4-chlorophenyl)-5-(1-methyl-4-(p...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C18H16ClN7O/c1-26-11-22-16(21-10-12-6-8-20-9-7-12)15(26)17-24-25-18(27-17)23-14-4-2-13(19)3-5-14/h2-9,11,21H,10H2,1H3,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 340 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178525
(CHEMBL203731 | N-(4-tert-butylphenyl)-5-(1-methyl-...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(cc2)C(C)(C)C)o1 Show InChI InChI=1S/C22H25N7O/c1-22(2,3)16-5-7-17(8-6-16)26-21-28-27-20(30-21)18-19(25-14-29(18)4)24-13-15-9-11-23-12-10-15/h5-12,14,24H,13H2,1-4H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178515
(CHEMBL203119 | N-(4-isopropylphenyl)-5-(1-methyl-4...)Show SMILES CC(C)c1ccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)cc1 Show InChI InChI=1S/C21H23N7O/c1-14(2)16-4-6-17(7-5-16)25-21-27-26-20(29-21)18-19(24-13-28(18)3)23-12-15-8-10-22-11-9-15/h4-11,13-14,23H,12H2,1-3H3,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178520
(CHEMBL202892 | N-(benzo[d][1,3]dioxol-5-ylmethyl)-...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(NCc2ccc3OCOc3c2)o1 Show InChI InChI=1S/C20H19N7O3/c1-27-11-24-18(22-9-13-4-6-21-7-5-13)17(27)19-25-26-20(30-19)23-10-14-2-3-15-16(8-14)29-12-28-15/h2-8,11,22H,9-10,12H2,1H3,(H,23,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178529
(CHEMBL205884 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(OC(F)(F)Cl)cc2)o1 Show InChI InChI=1S/C19H16ClF2N7O2/c1-29-11-25-16(24-10-12-6-8-23-9-7-12)15(29)17-27-28-18(30-17)26-13-2-4-14(5-3-13)31-19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178523
(CHEMBL204874 | N-(3,4-dichlorophenyl)-5-(1-methyl-...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Cl)c(Cl)c2)o1 Show InChI InChI=1S/C18H15Cl2N7O/c1-27-10-23-16(22-9-11-4-6-21-7-5-11)15(27)17-25-26-18(28-17)24-12-2-3-13(19)14(20)8-12/h2-8,10,22H,9H2,1H3,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178528
(CHEMBL205127 | N-(4-chloro-3-(trifluoromethyl)phen...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Cl)c(c2)C(F)(F)F)o1 Show InChI InChI=1S/C19H15ClF3N7O/c1-30-10-26-16(25-9-11-4-6-24-7-5-11)15(30)17-28-29-18(31-17)27-12-2-3-14(20)13(8-12)19(21,22)23/h2-8,10,25H,9H2,1H3,(H,27,29) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178509
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2cccc(OC(F)(F)F)c2)o1 Show InChI InChI=1S/C19H16F3N7O2/c1-29-11-25-16(24-10-12-5-7-23-8-6-12)15(29)17-27-28-18(30-17)26-13-3-2-4-14(9-13)31-19(20,21)22/h2-9,11,24H,10H2,1H3,(H,26,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178513
(CHEMBL203056 | N-(4-chlorophenyl)-5-(1-methyl-4-(p...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C18H16ClN7O/c1-26-11-22-16(21-10-12-6-8-20-9-7-12)15(26)17-24-25-18(27-17)23-14-4-2-13(19)3-5-14/h2-9,11,21H,10H2,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178519
(CHEMBL378592 | N-(3,4-dimethoxyphenyl)-5-(1-methyl...)Show SMILES COc1ccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)cc1OC Show InChI InChI=1S/C20H21N7O3/c1-27-12-23-18(22-11-13-6-8-21-9-7-13)17(27)19-25-26-20(30-19)24-14-4-5-15(28-2)16(10-14)29-3/h4-10,12,22H,11H2,1-3H3,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178521
(CHEMBL379908 | N-(2-fluoro-4-methylphenyl)-5-(1-me...)Show SMILES Cc1ccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)c(F)c1 Show InChI InChI=1S/C19H18FN7O/c1-12-3-4-15(14(20)9-12)24-19-26-25-18(28-19)16-17(23-11-27(16)2)22-10-13-5-7-21-8-6-13/h3-9,11,22H,10H2,1-2H3,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178521
(CHEMBL379908 | N-(2-fluoro-4-methylphenyl)-5-(1-me...)Show SMILES Cc1ccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)c(F)c1 Show InChI InChI=1S/C19H18FN7O/c1-12-3-4-15(14(20)9-12)24-19-26-25-18(28-19)16-17(23-11-27(16)2)22-10-13-5-7-21-8-6-13/h3-9,11,22H,10H2,1-2H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178511
(CHEMBL203796 | N-(3-methoxyphenyl)-5-(1-methyl-4-(...)Show SMILES COc1cccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)c1 Show InChI InChI=1S/C19H19N7O2/c1-26-12-22-17(21-11-13-6-8-20-9-7-13)16(26)18-24-25-19(28-18)23-14-4-3-5-15(10-14)27-2/h3-10,12,21H,11H2,1-2H3,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178510
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show InChI InChI=1S/C19H19N7O/c1-13-4-3-5-15(10-13)23-19-25-24-18(27-19)16-17(22-12-26(16)2)21-11-14-6-8-20-9-7-14/h3-10,12,21H,11H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178508
(CHEMBL205463 | N-(4-bromophenyl)-5-(1-methyl-4-(py...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Br)cc2)o1 Show InChI InChI=1S/C18H16BrN7O/c1-26-11-22-16(21-10-12-6-8-20-9-7-12)15(26)17-24-25-18(27-17)23-14-4-2-13(19)3-5-14/h2-9,11,21H,10H2,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 730 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178515
(CHEMBL203119 | N-(4-isopropylphenyl)-5-(1-methyl-4...)Show SMILES CC(C)c1ccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)cc1 Show InChI InChI=1S/C21H23N7O/c1-14(2)16-4-6-17(7-5-16)25-21-27-26-20(29-21)18-19(24-13-28(18)3)23-12-15-8-10-22-11-9-15/h4-11,13-14,23H,12H2,1-3H3,(H,25,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 770 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178525
(CHEMBL203731 | N-(4-tert-butylphenyl)-5-(1-methyl-...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(cc2)C(C)(C)C)o1 Show InChI InChI=1S/C22H25N7O/c1-22(2,3)16-5-7-17(8-6-16)26-21-28-27-20(30-21)18-19(25-14-29(18)4)24-13-15-9-11-23-12-10-15/h5-12,14,24H,13H2,1-4H3,(H,26,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178507
(5-(4-(2-(benzo[d][1,3]dioxol-5-yl)ethylamino)-1-me...)Show SMILES Cn1cnc(NCCc2ccc3OCOc3c2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C21H19ClN6O3/c1-28-11-24-19(23-9-8-13-2-7-16-17(10-13)30-12-29-16)18(28)20-26-27-21(31-20)25-15-5-3-14(22)4-6-15/h2-7,10-11,23H,8-9,12H2,1H3,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 960 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178525
(CHEMBL203731 | N-(4-tert-butylphenyl)-5-(1-methyl-...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(cc2)C(C)(C)C)o1 Show InChI InChI=1S/C22H25N7O/c1-22(2,3)16-5-7-17(8-6-16)26-21-28-27-20(30-21)18-19(25-14-29(18)4)24-13-15-9-11-23-12-10-15/h5-12,14,24H,13H2,1-4H3,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178515
(CHEMBL203119 | N-(4-isopropylphenyl)-5-(1-methyl-4...)Show SMILES CC(C)c1ccc(Nc2nnc(o2)-c2c(NCc3ccncc3)ncn2C)cc1 Show InChI InChI=1S/C21H23N7O/c1-14(2)16-4-6-17(7-5-16)25-21-27-26-20(29-21)18-19(24-13-28(18)3)23-12-15-8-10-22-11-9-15/h4-11,13-14,23H,12H2,1-3H3,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178510
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show InChI InChI=1S/C19H19N7O/c1-13-4-3-5-15(10-13)23-19-25-24-18(27-19)16-17(22-12-26(16)2)21-11-14-6-8-20-9-7-14/h3-10,12,21H,11H2,1-2H3,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178508
(CHEMBL205463 | N-(4-bromophenyl)-5-(1-methyl-4-(py...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Br)cc2)o1 Show InChI InChI=1S/C18H16BrN7O/c1-26-11-22-16(21-10-12-6-8-20-9-7-12)15(26)17-24-25-18(27-17)23-14-4-2-13(19)3-5-14/h2-9,11,21H,10H2,1H3,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178507
(5-(4-(2-(benzo[d][1,3]dioxol-5-yl)ethylamino)-1-me...)Show SMILES Cn1cnc(NCCc2ccc3OCOc3c2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C21H19ClN6O3/c1-28-11-24-19(23-9-8-13-2-7-16-17(10-13)30-12-29-16)18(28)20-26-27-21(31-20)25-15-5-3-14(22)4-6-15/h2-7,10-11,23H,8-9,12H2,1H3,(H,25,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM21
(CHEMBL24828 | N-(4-bromo-2-fluorophenyl)-6-methoxy...)Show SMILES COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1 Show InChI InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178506
(5-(4-(3,4-difluorobenzylamino)-1-methyl-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccc(F)c(F)c2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C19H15ClF2N6O/c1-28-10-24-17(23-9-11-2-7-14(21)15(22)8-11)16(28)18-26-27-19(29-18)25-13-5-3-12(20)4-6-13/h2-8,10,23H,9H2,1H3,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178531
(5-(4-((1H-indazol-5-yl)methylamino)-1-methyl-1H-im...)Show SMILES Cn1cnc(NCc2ccc3[nH]ncc3c2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C20H17ClN8O/c1-29-11-23-18(22-9-12-2-7-16-13(8-12)10-24-26-16)17(29)19-27-28-20(30-19)25-15-5-3-14(21)4-6-15/h2-8,10-11,22H,9H2,1H3,(H,24,26)(H,25,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178532
(CHEMBL205464 | biphenyl-4-yl-(5-{3-methyl-5-[(pyri...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(cc2)-c2ccccc2)o1 Show InChI InChI=1S/C24H21N7O/c1-31-16-27-22(26-15-17-11-13-25-14-12-17)21(31)23-29-30-24(32-23)28-20-9-7-19(8-10-20)18-5-3-2-4-6-18/h2-14,16,26H,15H2,1H3,(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178506
(5-(4-(3,4-difluorobenzylamino)-1-methyl-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccc(F)c(F)c2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C19H15ClF2N6O/c1-28-10-24-17(23-9-11-2-7-14(21)15(22)8-11)16(28)18-26-27-19(29-18)25-13-5-3-12(20)4-6-13/h2-8,10,23H,9H2,1H3,(H,25,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178522
(CHEMBL378165 | N-(4-chlorophenyl)-5-(1-methyl-4-(q...)Show SMILES Cn1cnc(NCc2cccc3ncccc23)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H18ClN7O/c1-30-13-26-20(25-12-14-4-2-6-18-17(14)5-3-11-24-18)19(30)21-28-29-22(31-21)27-16-9-7-15(23)8-10-16/h2-11,13,25H,12H2,1H3,(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178506
(5-(4-(3,4-difluorobenzylamino)-1-methyl-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccc(F)c(F)c2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C19H15ClF2N6O/c1-28-10-24-17(23-9-11-2-7-14(21)15(22)8-11)16(28)18-26-27-19(29-18)25-13-5-3-12(20)4-6-13/h2-8,10,23H,9H2,1H3,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178522
(CHEMBL378165 | N-(4-chlorophenyl)-5-(1-methyl-4-(q...)Show SMILES Cn1cnc(NCc2cccc3ncccc23)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H18ClN7O/c1-30-13-26-20(25-12-14-4-2-6-18-17(14)5-3-11-24-18)19(30)21-28-29-22(31-21)27-16-9-7-15(23)8-10-16/h2-11,13,25H,12H2,1H3,(H,27,29) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178517
(CHEMBL204718 | N-(4-chlorophenyl)-5-(1-methyl-4-(q...)Show SMILES Cn1cnc(NCc2ccc3ccccc3n2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H18ClN7O/c1-30-13-25-20(24-12-17-9-6-14-4-2-3-5-18(14)26-17)19(30)21-28-29-22(31-21)27-16-10-7-15(23)8-11-16/h2-11,13,24H,12H2,1H3,(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178532
(CHEMBL205464 | biphenyl-4-yl-(5-{3-methyl-5-[(pyri...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(cc2)-c2ccccc2)o1 Show InChI InChI=1S/C24H21N7O/c1-31-16-27-22(26-15-17-11-13-25-14-12-17)21(31)23-29-30-24(32-23)28-20-9-7-19(8-10-20)18-5-3-2-4-6-18/h2-14,16,26H,15H2,1H3,(H,28,30) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178516
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show InChI InChI=1S/C19H19N7O/c1-13-5-3-4-6-15(13)23-19-25-24-18(27-19)16-17(22-12-26(16)2)21-11-14-7-9-20-10-8-14/h3-10,12,21H,11H2,1-2H3,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178530
(CHEMBL206742 | N-(4-chlorophenyl)-5-(1-methyl-4-(p...)Show SMILES Cn1cnc(NCc2cccnc2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C18H16ClN7O/c1-26-11-22-16(21-10-12-3-2-8-20-9-12)15(26)17-24-25-18(27-17)23-14-6-4-13(19)5-7-14/h2-9,11,21H,10H2,1H3,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178514
(CHEMBL202904 | N-(4-chlorophenyl)-5-(1-methyl-4-(p...)Show SMILES Cn1cnc(NCc2ccccn2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C18H16ClN7O/c1-26-11-22-16(21-10-14-4-2-3-9-20-14)15(26)17-24-25-18(27-17)23-13-7-5-12(19)6-8-13/h2-9,11,21H,10H2,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178527
(CHEMBL204312 | N-(2-methoxyphenyl)-5-(1-methyl-4-(...)Show InChI InChI=1S/C19H19N7O2/c1-26-12-22-17(21-11-13-7-9-20-10-8-13)16(26)18-24-25-19(28-18)23-14-5-3-4-6-15(14)27-2/h3-10,12,21H,11H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178527
(CHEMBL204312 | N-(2-methoxyphenyl)-5-(1-methyl-4-(...)Show InChI InChI=1S/C19H19N7O2/c1-26-12-22-17(21-11-13-7-9-20-10-8-13)16(26)18-24-25-19(28-18)23-14-5-3-4-6-15(14)27-2/h3-10,12,21H,11H2,1-2H3,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178514
(CHEMBL202904 | N-(4-chlorophenyl)-5-(1-methyl-4-(p...)Show SMILES Cn1cnc(NCc2ccccn2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C18H16ClN7O/c1-26-11-22-16(21-10-14-4-2-3-9-20-14)15(26)17-24-25-18(27-17)23-13-7-5-12(19)6-8-13/h2-9,11,21H,10H2,1H3,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178507
(5-(4-(2-(benzo[d][1,3]dioxol-5-yl)ethylamino)-1-me...)Show SMILES Cn1cnc(NCCc2ccc3OCOc3c2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C21H19ClN6O3/c1-28-11-24-19(23-9-8-13-2-7-16-17(10-13)30-12-29-16)18(28)20-26-27-21(31-20)25-15-5-3-14(22)4-6-15/h2-7,10-11,23H,8-9,12H2,1H3,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178530
(CHEMBL206742 | N-(4-chlorophenyl)-5-(1-methyl-4-(p...)Show SMILES Cn1cnc(NCc2cccnc2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C18H16ClN7O/c1-26-11-22-16(21-10-12-3-2-8-20-9-12)15(26)17-24-25-18(27-17)23-14-6-4-13(19)5-7-14/h2-9,11,21H,10H2,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178531
(5-(4-((1H-indazol-5-yl)methylamino)-1-methyl-1H-im...)Show SMILES Cn1cnc(NCc2ccc3[nH]ncc3c2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C20H17ClN8O/c1-29-11-23-18(22-9-12-2-7-16-13(8-12)10-24-26-16)17(29)19-27-28-20(30-19)25-15-5-3-14(21)4-6-15/h2-8,10-11,22H,9H2,1H3,(H,24,26)(H,25,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178518
(CHEMBL383126 | N-(4-benzylphenyl)-5-(1-methyl-4-(p...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Cc3ccccc3)cc2)o1 Show InChI InChI=1S/C25H23N7O/c1-32-17-28-23(27-16-20-11-13-26-14-12-20)22(32)24-30-31-25(33-24)29-21-9-7-19(8-10-21)15-18-5-3-2-4-6-18/h2-14,17,27H,15-16H2,1H3,(H,29,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178517
(CHEMBL204718 | N-(4-chlorophenyl)-5-(1-methyl-4-(q...)Show SMILES Cn1cnc(NCc2ccc3ccccc3n2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H18ClN7O/c1-30-13-25-20(24-12-17-9-6-14-4-2-3-5-18(14)26-17)19(30)21-28-29-22(31-21)27-16-10-7-15(23)8-11-16/h2-11,13,24H,12H2,1H3,(H,27,29) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178530
(CHEMBL206742 | N-(4-chlorophenyl)-5-(1-methyl-4-(p...)Show SMILES Cn1cnc(NCc2cccnc2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C18H16ClN7O/c1-26-11-22-16(21-10-12-3-2-8-20-9-12)15(26)17-24-25-18(27-17)23-14-6-4-13(19)5-7-14/h2-9,11,21H,10H2,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178531
(5-(4-((1H-indazol-5-yl)methylamino)-1-methyl-1H-im...)Show SMILES Cn1cnc(NCc2ccc3[nH]ncc3c2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C20H17ClN8O/c1-29-11-23-18(22-9-12-2-7-16-13(8-12)10-24-26-16)17(29)19-27-28-20(30-19)25-15-5-3-14(21)4-6-15/h2-8,10-11,22H,9H2,1H3,(H,24,26)(H,25,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178512
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Oc3ccccc3)cc2)o1 Show InChI InChI=1S/C24H21N7O2/c1-31-16-27-22(26-15-17-11-13-25-14-12-17)21(31)23-29-30-24(33-23)28-18-7-9-20(10-8-18)32-19-5-3-2-4-6-19/h2-14,16,26H,15H2,1H3,(H,28,30) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178522
(CHEMBL378165 | N-(4-chlorophenyl)-5-(1-methyl-4-(q...)Show SMILES Cn1cnc(NCc2cccc3ncccc23)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H18ClN7O/c1-30-13-26-20(25-12-14-4-2-6-18-17(14)5-3-11-24-18)19(30)21-28-29-22(31-21)27-16-9-7-15(23)8-10-16/h2-11,13,25H,12H2,1H3,(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178512
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Oc3ccccc3)cc2)o1 Show InChI InChI=1S/C24H21N7O2/c1-31-16-27-22(26-15-17-11-13-25-14-12-17)21(31)23-29-30-24(33-23)28-18-7-9-20(10-8-18)32-19-5-3-2-4-6-19/h2-14,16,26H,15H2,1H3,(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178517
(CHEMBL204718 | N-(4-chlorophenyl)-5-(1-methyl-4-(q...)Show SMILES Cn1cnc(NCc2ccc3ccccc3n2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H18ClN7O/c1-30-13-25-20(24-12-17-9-6-14-4-2-3-5-18(14)26-17)19(30)21-28-29-22(31-21)27-16-10-7-15(23)8-11-16/h2-11,13,24H,12H2,1H3,(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50178518
(CHEMBL383126 | N-(4-benzylphenyl)-5-(1-methyl-4-(p...)Show SMILES Cn1cnc(NCc2ccncc2)c1-c1nnc(Nc2ccc(Cc3ccccc3)cc2)o1 Show InChI InChI=1S/C25H23N7O/c1-32-17-28-23(27-16-20-11-13-26-14-12-20)22(32)24-30-31-25(33-24)29-21-9-7-19(8-10-21)15-18-5-3-2-4-6-18/h2-14,17,27H,15-16H2,1H3,(H,29,31) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178514
(CHEMBL202904 | N-(4-chlorophenyl)-5-(1-methyl-4-(p...)Show SMILES Cn1cnc(NCc2ccccn2)c1-c1nnc(Nc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C18H16ClN7O/c1-26-11-22-16(21-10-14-4-2-3-9-20-14)15(26)17-24-25-18(27-17)23-13-7-5-12(19)6-8-13/h2-9,11,21H,10H2,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 in 293 adenovirus transfected kidney cells by cell-based ELISA assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50178516
(5-(1-methyl-4-(pyridin-4-ylmethylamino)-1H-imidazo...)Show InChI InChI=1S/C19H19N7O/c1-13-5-3-4-6-15(13)23-19-25-24-18(27-19)16-17(22-12-26(16)2)21-11-14-7-9-20-10-8-14/h3-10,12,21H,11H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 by enzymatic assay |
Bioorg Med Chem Lett 16: 1440-4 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.033
BindingDB Entry DOI: 10.7270/Q2NP240T |
More data for this
Ligand-Target Pair | |
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