Affinity Data by PubMed id=16420053

PubMed code 16420053

Found 4 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Orphan methyltransferase M.SssI (Spiroplasma monobiae strain MQ-1)	BDBM50180789 (1,2-bis(7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3-y...) Show SMILES Cc1ccn2c(CCc3nnc4cc(C)ccn34)nnc2c1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant CpG methylase M.SssI				J Med Chem 49: 678-83 (2006) Article DOI: 10.1021/jm050844z BindingDB Entry DOI: 10.7270/Q20G3JR2
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
Orphan methyltransferase M.SssI (Spiroplasma monobiae strain MQ-1)	BDBM50180790 (2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)prop...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant CpG methylase M.SssI				J Med Chem 49: 678-83 (2006) Article DOI: 10.1021/jm050844z BindingDB Entry DOI: 10.7270/Q20G3JR2
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 1 (Homo sapiens (Human))	BDBM50180790 (2-(1,3-dioxoisoindolin-2-yl)-3-(1H-indol-3-yl)prop...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against DNA methyl transferase in leukemic NALM6 cells				J Med Chem 49: 678-83 (2006) Article DOI: 10.1021/jm050844z BindingDB Entry DOI: 10.7270/Q20G3JR2
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 1 (Homo sapiens (Human))	BDBM50180789 (1,2-bis(7-methyl-[1,2,4]triazolo[4,3-a]pyridin-3-y...) Show SMILES Cc1ccn2c(CCc3nnc4cc(C)ccn34)nnc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Polish Academy of Sciences Curated by ChEMBL					Assay Description Inhibitory activity against DNA methyl transferase in leukemic NALM6 cells				J Med Chem 49: 678-83 (2006) Article DOI: 10.1021/jm050844z BindingDB Entry DOI: 10.7270/Q20G3JR2
Polish Academy of Sciences Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%