Affinity Data by PubMed id=16434192

PubMed code 16434192

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50181042 (7-nitro-N-(5-(piperidin-1-yl)pentyl)benzo[c][1,2,5...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 16: 1938-40 (2006) Article DOI: 10.1016/j.bmcl.2005.12.084 BindingDB Entry DOI: 10.7270/Q237789Z
Johann Wolfgang Goethe-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50181043 (2-(5-(piperidin-1-yl)pentyl)-2H-isoindole-1-carbon...) Show SMILES N#Cc1n(CCCCCN2CCCCC2)cc2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 16: 1938-40 (2006) Article DOI: 10.1016/j.bmcl.2005.12.084 BindingDB Entry DOI: 10.7270/Q237789Z
Johann Wolfgang Goethe-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50181040 (2-(6-(piperidin-1-yl)hexyl)-2H-isoindole-1-carboni...) Show SMILES N#Cc1n(CCCCCCN2CCCCC2)cc2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 16: 1938-40 (2006) Article DOI: 10.1016/j.bmcl.2005.12.084 BindingDB Entry DOI: 10.7270/Q237789Z
Johann Wolfgang Goethe-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50181041 (7-nitro-N-(4-(piperidin-1-yl)butyl)benzo[c][1,2,5]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 16: 1938-40 (2006) Article DOI: 10.1016/j.bmcl.2005.12.084 BindingDB Entry DOI: 10.7270/Q237789Z
Johann Wolfgang Goethe-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50181045 (2-(4-(piperidin-1-yl)butyl)-2H-isoindole-1-carboni...) Show SMILES N#Cc1n(CCCCN2CCCCC2)cc2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	178	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 16: 1938-40 (2006) Article DOI: 10.1016/j.bmcl.2005.12.084 BindingDB Entry DOI: 10.7270/Q237789Z
Johann Wolfgang Goethe-Universität Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50181044 (2-(3-(piperidin-1-yl)propyl)-2H-isoindole-1-carbon...) Show SMILES N#Cc1n(CCCN2CCCCC2)cc2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	351	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Displacement of [125I]iodoproxyfan from human histamine H3 receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 16: 1938-40 (2006) Article DOI: 10.1016/j.bmcl.2005.12.084 BindingDB Entry DOI: 10.7270/Q237789Z
Johann Wolfgang Goethe-Universität Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%