Found 55 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50000832
(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)Show InChI InChI=1S/C23H21NO2S/c1-23(25-2,22-24-12-13-27-22)20-8-5-9-21(15-20)26-16-17-10-11-18-6-3-4-7-19(18)14-17/h3-15H,16H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50007052
(1-[3-(3-Phenyl-allyloxy)-phenyl]-1-thiazol-2-yl-pr...)Show InChI InChI=1S/C21H21NO2S/c1-2-21(23,20-22-13-15-25-20)18-11-6-12-19(16-18)24-14-7-10-17-8-4-3-5-9-17/h3-13,15-16,23H,2,14H2,1H3/b10-7+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50000857
(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)Show InChI InChI=1S/C24H23NO2S/c1-3-24(26-2,23-25-13-14-28-23)21-9-6-10-22(16-21)27-17-18-11-12-19-7-4-5-8-20(19)15-18/h4-16H,3,17H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50007040
(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)Show InChI InChI=1S/C24H21NO2S/c1-26-24(23-25-12-13-28-23)11-10-19-8-9-21(15-22(19)24)27-16-17-6-7-18-4-2-3-5-20(18)14-17/h2-9,12-15H,10-11,16H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50007040
(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)Show InChI InChI=1S/C24H21NO2S/c1-26-24(23-25-12-13-28-23)11-10-19-8-9-21(15-22(19)24)27-16-17-6-7-18-4-2-3-5-20(18)14-17/h2-9,12-15H,10-11,16H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-LPO) in rat basophilic leukemia (RBL) cells. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50000832
(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)Show InChI InChI=1S/C23H21NO2S/c1-23(25-2,22-24-12-13-27-22)20-8-5-9-21(15-20)26-16-17-10-11-18-6-3-4-7-19(18)14-17/h3-15H,16H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50000832
(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)Show InChI InChI=1S/C23H21NO2S/c1-23(25-2,22-24-12-13-27-22)20-8-5-9-21(15-20)26-16-17-10-11-18-6-3-4-7-19(18)14-17/h3-15H,16H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50007057
(1-[3-(3-Phenyl-prop-2-ynyloxy)-phenyl]-1-thiazol-2...)Show InChI InChI=1S/C21H19NO2S/c1-2-21(23,20-22-13-15-25-20)18-11-6-12-19(16-18)24-14-7-10-17-8-4-3-5-9-17/h3-6,8-9,11-13,15-16,23H,2,14H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50007040
(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)Show InChI InChI=1S/C24H21NO2S/c1-26-24(23-25-12-13-28-23)11-10-19-8-9-21(15-22(19)24)27-16-17-6-7-18-4-2-3-5-20(18)14-17/h2-9,12-15H,10-11,16H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | <30 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50007051
(1-[3-(Naphthalen-2-ylmethoxy)-phenyl]-1-thiazol-2-...)Show InChI InChI=1S/C24H23NO2S/c1-2-12-24(26,23-25-13-14-28-23)21-8-5-9-22(16-21)27-17-18-10-11-19-6-3-4-7-20(19)15-18/h3-11,13-16,26H,2,12,17H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50000857
(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)Show InChI InChI=1S/C24H23NO2S/c1-3-24(26-2,23-25-13-14-28-23)21-9-6-10-22(16-21)27-17-18-11-12-19-7-4-5-8-20(19)15-18/h4-16H,3,17H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50007042
(2-{Methoxy-[3-(naphthalen-2-ylmethoxy)-phenyl]-met...)Show InChI InChI=1S/C22H19NO2S/c1-24-21(22-23-11-12-26-22)19-7-4-8-20(14-19)25-15-16-9-10-17-5-2-3-6-18(17)13-16/h2-14,21H,15H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50000857
(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)Show InChI InChI=1S/C24H23NO2S/c1-3-24(26-2,23-25-13-14-28-23)21-9-6-10-22(16-21)27-17-18-11-12-19-7-4-5-8-20(19)15-18/h4-16H,3,17H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50000832
(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)Show InChI InChI=1S/C23H21NO2S/c1-23(25-2,22-24-12-13-27-22)20-8-5-9-21(15-20)26-16-17-10-11-18-6-3-4-7-19(18)14-17/h3-15H,16H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50000832
(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)Show InChI InChI=1S/C23H21NO2S/c1-23(25-2,22-24-12-13-27-22)20-8-5-9-21(15-20)26-16-17-10-11-18-6-3-4-7-19(18)14-17/h3-15H,16H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50000857
(2-(1-methoxy-1-(3-(naphthalen-2-ylmethoxy)phenyl)p...)Show InChI InChI=1S/C24H23NO2S/c1-3-24(26-2,23-25-13-14-28-23)21-9-6-10-22(16-21)27-17-18-11-12-19-7-4-5-8-20(19)15-18/h4-16H,3,17H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007055
(4-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)Show InChI InChI=1S/C24H23NO2S/c1-3-24(26-2,23-16-28-17-25-23)21-9-6-10-22(14-21)27-15-18-11-12-19-7-4-5-8-20(19)13-18/h4-14,16-17H,3,15H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007056
(1-Thiazol-2-yl-1-[3-(3-o-tolyl-prop-2-ynyloxy)-phe...)Show InChI InChI=1S/C22H21NO2S/c1-3-22(24,21-23-13-15-26-21)19-11-6-12-20(16-19)25-14-7-10-18-9-5-4-8-17(18)2/h4-6,8-9,11-13,15-16,24H,3,14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007040
(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)Show InChI InChI=1S/C24H21NO2S/c1-26-24(23-25-12-13-28-23)11-10-19-8-9-21(15-22(19)24)27-16-17-6-7-18-4-2-3-5-20(18)14-17/h2-9,12-15H,10-11,16H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007040
(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)Show InChI InChI=1S/C24H21NO2S/c1-26-24(23-25-12-13-28-23)11-10-19-8-9-21(15-22(19)24)27-16-17-6-7-18-4-2-3-5-20(18)14-17/h2-9,12-15H,10-11,16H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50000832
(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)Show InChI InChI=1S/C23H21NO2S/c1-23(25-2,22-24-12-13-27-22)20-8-5-9-21(15-20)26-16-17-10-11-18-6-3-4-7-19(18)14-17/h3-15H,16H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50007047
(1-[3-(3,4-Difluoro-benzyloxy)-phenyl]-1-thiazol-2-...)Show InChI InChI=1S/C19H17F2NO2S/c1-2-19(23,18-22-8-9-25-18)14-4-3-5-15(11-14)24-12-13-6-7-16(20)17(21)10-13/h3-11,23H,2,12H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50000832
(2-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)Show InChI InChI=1S/C23H21NO2S/c1-23(25-2,22-24-12-13-27-22)20-8-5-9-21(15-20)26-16-17-10-11-18-6-3-4-7-19(18)14-17/h3-15H,16H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007052
(1-[3-(3-Phenyl-allyloxy)-phenyl]-1-thiazol-2-yl-pr...)Show InChI InChI=1S/C21H21NO2S/c1-2-21(23,20-22-13-15-25-20)18-11-6-12-19(16-18)24-14-7-10-17-8-4-3-5-9-17/h3-13,15-16,23H,2,14H2,1H3/b10-7+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50007040
(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)Show InChI InChI=1S/C24H21NO2S/c1-26-24(23-25-12-13-28-23)11-10-19-8-9-21(15-22(19)24)27-16-17-6-7-18-4-2-3-5-20(18)14-17/h2-9,12-15H,10-11,16H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50007040
(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)Show InChI InChI=1S/C24H21NO2S/c1-26-24(23-25-12-13-28-23)11-10-19-8-9-21(15-22(19)24)27-16-17-6-7-18-4-2-3-5-20(18)14-17/h2-9,12-15H,10-11,16H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50007060
(1-(4-Methyl-thiazol-2-yl)-1-[3-(naphthalen-2-ylmet...)Show SMILES CCC(O)(c1nc(C)cs1)c1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C24H23NO2S/c1-3-24(26,23-25-17(2)16-28-23)21-9-6-10-22(14-21)27-15-18-11-12-19-7-4-5-8-20(19)13-18/h4-14,16,26H,3,15H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 820 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50007048
(2-Methyl-1-[3-(naphthalen-2-ylmethoxy)-phenyl]-1-t...)Show SMILES CC(C)C(O)(c1nccs1)c1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C24H23NO2S/c1-17(2)24(26,23-25-12-13-28-23)21-8-5-9-22(15-21)27-16-18-10-11-19-6-3-4-7-20(19)14-18/h3-15,17,26H,16H2,1-2H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007057
(1-[3-(3-Phenyl-prop-2-ynyloxy)-phenyl]-1-thiazol-2...)Show InChI InChI=1S/C21H19NO2S/c1-2-21(23,20-22-13-15-25-20)18-11-6-12-19(16-18)24-14-7-10-17-8-4-3-5-9-17/h3-6,8-9,11-13,15-16,23H,2,14H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007063
(1-[3-(3,4-Dichloro-benzyloxy)-phenyl]-1-thiazol-2-...)Show SMILES CCC(O)(c1nccs1)c1cccc(OCc2ccc(Cl)c(Cl)c2)c1 Show InChI InChI=1S/C19H17Cl2NO2S/c1-2-19(23,18-22-8-9-25-18)14-4-3-5-15(11-14)24-12-13-6-7-16(20)17(21)10-13/h3-11,23H,2,12H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007058
(1-Thiazol-2-yl-1-[3-(3-m-tolyl-prop-2-ynyloxy)-phe...)Show InChI InChI=1S/C22H21NO2S/c1-3-22(24,21-23-12-14-26-21)19-10-5-11-20(16-19)25-13-6-9-18-8-4-7-17(2)15-18/h4-5,7-8,10-12,14-16,24H,3,13H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007062
(2-{1-Methoxy-1-[3-(naphthalen-1-ylmethoxy)-phenyl]...)Show InChI InChI=1S/C24H23NO2S/c1-3-24(26-2,23-25-14-15-28-23)20-11-7-12-21(16-20)27-17-19-10-6-9-18-8-4-5-13-22(18)19/h4-16H,3,17H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007053
(CHEMBL73720 | [3-(Naphthalen-2-ylmethoxy)-phenyl]-...)Show InChI InChI=1S/C21H17NO2S/c23-20(21-22-10-11-25-21)18-6-3-7-19(13-18)24-14-15-8-9-16-4-1-2-5-17(16)12-15/h1-13,20,23H,14H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 5.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50007042
(2-{Methoxy-[3-(naphthalen-2-ylmethoxy)-phenyl]-met...)Show InChI InChI=1S/C22H19NO2S/c1-24-21(22-23-11-12-26-22)19-7-4-8-20(14-19)25-15-16-9-10-17-5-2-3-6-18(17)13-16/h2-14,21H,15H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007043
((3-Decyloxy-phenyl)-(5-methyl-1H-imidazol-2-yl)-me...)Show InChI InChI=1S/C21H32N2O2/c1-3-4-5-6-7-8-9-10-14-25-19-13-11-12-18(15-19)20(24)21-22-16-17(2)23-21/h11-13,15-16,20,24H,3-10,14H2,1-2H3,(H,22,23) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007054
(5-{1-Methoxy-1-[3-(naphthalen-2-ylmethoxy)-phenyl]...)Show InChI InChI=1S/C24H23NO2S/c1-3-24(26-2,23-15-25-17-28-23)21-9-6-10-22(14-21)27-16-18-11-12-19-7-4-5-8-20(19)13-18/h4-15,17H,3,16H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007050
(CHEMBL71399 | [3-(Biphenyl-4-ylmethoxy)-phenyl]-(5...)Show SMILES Cc1cnc([nH]1)C(O)c1cccc(OCc2ccc(cc2)-c2ccccc2)c1 Show InChI InChI=1S/C24H22N2O2/c1-17-15-25-24(26-17)23(27)21-8-5-9-22(14-21)28-16-18-10-12-20(13-11-18)19-6-3-2-4-7-19/h2-15,23,27H,16H2,1H3,(H,25,26) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007042
(2-{Methoxy-[3-(naphthalen-2-ylmethoxy)-phenyl]-met...)Show InChI InChI=1S/C22H19NO2S/c1-24-21(22-23-11-12-26-22)19-7-4-8-20(14-19)25-15-16-9-10-17-5-2-3-6-18(17)13-16/h2-14,21H,15H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007041
((5-Methyl-1H-imidazol-2-yl)-[3-(naphthalen-2-ylmet...)Show SMILES Cc1cnc([nH]1)C(O)c1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C22H20N2O2/c1-15-13-23-22(24-15)21(25)19-7-4-8-20(12-19)26-14-16-9-10-17-5-2-3-6-18(17)11-16/h2-13,21,25H,14H2,1H3,(H,23,24) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007051
(1-[3-(Naphthalen-2-ylmethoxy)-phenyl]-1-thiazol-2-...)Show InChI InChI=1S/C24H23NO2S/c1-2-12-24(26,23-25-13-14-28-23)21-8-5-9-22(16-21)27-17-18-10-11-19-6-3-4-7-20(19)15-18/h3-11,13-16,26H,2,12,17H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007044
(1-[3-(3-Phenyl-propoxy)-phenyl]-1-thiazol-2-yl-pro...)Show InChI InChI=1S/C21H23NO2S/c1-2-21(23,20-22-13-15-25-20)18-11-6-12-19(16-18)24-14-7-10-17-8-4-3-5-9-17/h3-6,8-9,11-13,15-16,23H,2,7,10,14H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007042
(2-{Methoxy-[3-(naphthalen-2-ylmethoxy)-phenyl]-met...)Show InChI InChI=1S/C22H19NO2S/c1-24-21(22-23-11-12-26-22)19-7-4-8-20(14-19)25-15-16-9-10-17-5-2-3-6-18(17)13-16/h2-14,21H,15H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in guinea pig. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Mus musculus) | BDBM50007045
(2-[1-Methoxy-4-(naphthalen-2-ylmethoxy)-indan-1-yl...)Show InChI InChI=1S/C24H21NO2S/c1-26-24(23-25-13-14-28-23)12-11-20-21(24)7-4-8-22(20)27-16-17-9-10-18-5-2-3-6-19(18)15-17/h2-10,13-15H,11-12,16H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in mouse macrophages. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50007040
(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)Show InChI InChI=1S/C24H21NO2S/c1-26-24(23-25-12-13-28-23)11-10-19-8-9-21(15-22(19)24)27-16-17-6-7-18-4-2-3-5-20(18)14-17/h2-9,12-15H,10-11,16H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-LPO) in rat basophilic leukemia (RBL) cells. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007059
(1-Thiazol-2-yl-1-[3-(3-p-tolyl-prop-2-ynyloxy)-phe...)Show InChI InChI=1S/C22H21NO2S/c1-3-22(24,21-23-13-15-26-21)19-7-4-8-20(16-19)25-14-5-6-18-11-9-17(2)10-12-18/h4,7-13,15-16,24H,3,14H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50007043
((3-Decyloxy-phenyl)-(5-methyl-1H-imidazol-2-yl)-me...)Show InChI InChI=1S/C21H32N2O2/c1-3-4-5-6-7-8-9-10-14-25-19-13-11-12-18(15-19)20(24)21-22-16-17(2)23-21/h11-13,15-16,20,24H,3-10,14H2,1-2H3,(H,22,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50007041
((5-Methyl-1H-imidazol-2-yl)-[3-(naphthalen-2-ylmet...)Show SMILES Cc1cnc([nH]1)C(O)c1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C22H20N2O2/c1-15-13-23-22(24-15)21(25)19-7-4-8-20(12-19)26-14-16-9-10-17-5-2-3-6-18(17)11-16/h2-13,21,25H,14H2,1H3,(H,23,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Rattus norvegicus) | BDBM50007053
(CHEMBL73720 | [3-(Naphthalen-2-ylmethoxy)-phenyl]-...)Show InChI InChI=1S/C21H17NO2S/c23-20(21-22-10-11-25-21)18-6-3-7-19(13-18)24-14-15-8-9-16-4-1-2-5-17(16)12-15/h1-13,20,23H,14H2 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Compound was tested for the inhibition of 5-lipoxygenase (5-Lpo) in rat whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007040
(2-[1-Methoxy-6-(naphthalen-2-ylmethoxy)-indan-1-yl...)Show InChI InChI=1S/C24H21NO2S/c1-26-24(23-25-12-13-28-23)11-10-19-8-9-21(15-22(19)24)27-16-17-6-7-18-4-2-3-5-20(18)14-17/h2-9,12-15H,10-11,16H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007061
(2-[6-(Naphthalen-2-ylmethoxy)-indan-1-yl]-thiazole...)Show InChI InChI=1S/C23H19NOS/c1-2-4-19-13-16(5-6-17(19)3-1)15-25-20-9-7-18-8-10-21(22(18)14-20)23-24-11-12-26-23/h1-7,9,11-14,21H,8,10,15H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007046
(2-(3-Methoxy-indan-5-yloxymethyl)-naphthalene | CH...)Show InChI InChI=1S/C21H20O2/c1-22-21-11-9-17-8-10-19(13-20(17)21)23-14-15-6-7-16-4-2-3-5-18(16)12-15/h2-8,10,12-13,21H,9,11,14H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007048
(2-Methyl-1-[3-(naphthalen-2-ylmethoxy)-phenyl]-1-t...)Show SMILES CC(C)C(O)(c1nccs1)c1cccc(OCc2ccc3ccccc3c2)c1 Show InChI InChI=1S/C24H23NO2S/c1-17(2)24(26,23-25-12-13-28-23)21-8-5-9-22(15-21)27-16-18-10-11-19-6-3-4-7-20(19)14-18/h3-15,17,26H,16H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007045
(2-[1-Methoxy-4-(naphthalen-2-ylmethoxy)-indan-1-yl...)Show InChI InChI=1S/C24H21NO2S/c1-26-24(23-25-13-14-28-23)12-11-20-21(24)7-4-8-22(20)27-16-17-9-10-18-5-2-3-6-19(18)15-17/h2-10,13-15H,11-12,16H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007049
(2-{1-Methoxy-1-[2-(naphthalen-2-ylmethoxy)-phenyl]...)Show InChI InChI=1S/C24H23NO2S/c1-3-24(26-2,23-25-14-15-28-23)21-10-6-7-11-22(21)27-17-18-12-13-19-8-4-5-9-20(19)16-18/h4-16H,3,17H2,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human)) | BDBM50007047
(1-[3-(3,4-Difluoro-benzyloxy)-phenyl]-1-thiazol-2-...)Show InChI InChI=1S/C19H17F2NO2S/c1-2-19(23,18-22-8-9-25-18)14-4-3-5-15(11-14)24-12-13-6-7-16(20)17(21)10-13/h3-11,23H,2,12H2,1H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals
Curated by ChEMBL
| Assay Description
Inhibition of 5-lipoxygenase in human whole blood. |
J Med Chem 34: 2176-86 (1991)
BindingDB Entry DOI: 10.7270/Q2S46QX6 |
More data for this
Ligand-Target Pair | |
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