Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM24183 (4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM24182 (4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM24182 (4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007118 (4-Amino-3-(5-chloro-thiophen-2-yl)-butyric acid | ...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007121 (4-Amino-3-(2-chloro-phenyl)-butyric acid | CHEMBL8...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50368295 (CHEMBL301492) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007107 (4-Amino-3-(5-methyl-thiophen-2-yl)-butyric acid | ...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007108 (4-Amino-3-(5-bromo-thiophen-2-yl)-butyric acid | C...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007117 (4-Amino-3-thiophen-2-yl-butyric acid | CHEMBL31547...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 9.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007109 (4-Amino-3-(3-chloro-phenyl)-butyric acid | CHEMBL3...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007113 (4-Amino-3-thiophen-3-yl-butyric acid | CHEMBL87856) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007110 (4-Amino-3-(4-bromo-thiophen-2-yl)-butyric acid | C...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007111 (4-Amino-3-(4-chloro-thiophen-2-yl)-butyric acid | ...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.53E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007120 (4-Amino-3-(4-hydroxy-phenyl)-butyric acid | CHEMBL...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007112 (4-Amino-3-(5-methyl-furan-2-yl)-butyric acid | CHE...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007114 (4-Amino-3-furan-2-yl-butyric acid | CHEMBL85880) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007119 (4-Amino-3-phenyl-butyric acid | CHEMBL53073) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gamma-aminobutyric acid type B receptor subunit 1/2 (Rattus norvegicus (Rat)) | BDBM50007116 (4-Amino-3-(3-methyl-thiophen-2-yl)-butyric acid | ...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.24E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Pharmacie Chimique, Facult� de Pharmacie, Lille, France. Curated by ChEMBL | Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor. | J Med Chem 34: 2557-60 (1991) BindingDB Entry DOI: 10.7270/Q2GQ6ZC0 | |||||||||||
More data for this Ligand-Target Pair |