Affinity Data by PubMed id=16570923

PubMed code 16570923

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184908 (CHEMBL402661 \| cypate-[(RGD)4-NH2]1) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.9	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184904 (CHEMBL206344 \| cyclo(RGDfV) (control)) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28.7	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184902 (CHEMBL407126 \| cyclo[RGDfK(cypate)]) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63.9	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184906 (CHEMBL429568 \| cypate-[(RGD)4-NH2]2) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79.6	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184903 (CHEMBL415188 \| cypate-[(RGD)2-NH2]2) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184905 (CHEMBL413898 \| cypate-[(RGD)3-NH2]2) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184907 (CHEMBL412767 \| cypate-[(RGD)3-NH2]1) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50184909 (CHEMBL438186 \| cypate-[(RGD)2-NH2]1) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	730	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Curated by ChEMBL					Assay Description Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor				J Med Chem 49: 2268-75 (2006) Article DOI: 10.1021/jm050947h BindingDB Entry DOI: 10.7270/Q24T6KK2
Washington University Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%