Affinity Data by PubMed id=16647256

PubMed code 16647256

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50186088 ((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of human DPP1				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50186090 ((S)-2-amino-N-((S)-2-(4-chlorophenyl)-1-cyanoethyl...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of human DPP1				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50186089 ((S)-2-amino-N-((S,E)-1-cyano-4-phenylbut-3-enyl)bu...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of human DPP1				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50186091 ((S)-2-amino-N-((S)-1-cyano-2-phenylethyl)butanamid...) Show SMILES CC[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C#N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	172	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of human DPP1				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50186093 ((S)-2-amino-N-((S)-1-cyano-3-phenylpropyl)butanami...) Show SMILES CC[C@H](N)C(=O)N[C@@H](CCc1ccccc1)C#N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	822	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of human DPP1				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50186088 ((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of CYP3A4				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50186094 ((S)-2-amino-N-(1-cyano-2-phenylethyl)acetamide \| C...) Show SMILES NCC(=O)N[C@@H](Cc1ccccc1)C#N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of human DPP1				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50186087 ((2S)-2-amino-N-(1-cyano-2-phenylethyl)-3-phenylpro...) Show SMILES N[C@@H](Cc1ccccc1)C(=O)NC(Cc1ccccc1)C#N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of human DPP1				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50186092 ((S)-N-((S)-1-cyano-2-phenylethyl)pyrrolidine-2-car...) Show SMILES O=C(N[C@@H](Cc1ccccc1)C#N)[C@@H]1CCCN1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of human DPP1				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50186088 ((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of Cathepsin B				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Pro-cathepsin H (Homo sapiens (Human))	BDBM50186088 ((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of Cathepsin H				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50186088 ((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of Cathepsin L				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50186088 ((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50186088 ((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of CYP1A2				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50186088 ((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of CYP2C9				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50186088 ((S)-2-amino-N-((S)-2-(biphenyl-4-yl)-1-cyanoethyl)...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Arpida A/S Curated by ChEMBL					Assay Description Inhibition of CYP2C19				Bioorg Med Chem Lett 16: 3614-7 (2006) Article DOI: 10.1016/j.bmcl.2006.01.102 BindingDB Entry DOI: 10.7270/Q2639PC4
Arpida A/S Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%