Affinity Data by PubMed id=16759856

PubMed code 16759856

Found 9 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50188774 (1-(3,4-dichlorophenyl)-3-hydroxyurea \| CHEMBL21334...) Show SMILES ONC(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA2				Bioorg Med Chem Lett 16: 4316-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.068 BindingDB Entry DOI: 10.7270/Q2HX1C9J
Università degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50188774 (1-(3,4-dichlorophenyl)-3-hydroxyurea \| CHEMBL21334...) Show SMILES ONC(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA9				Bioorg Med Chem Lett 16: 4316-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.068 BindingDB Entry DOI: 10.7270/Q2HX1C9J
Università degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50188774 (1-(3,4-dichlorophenyl)-3-hydroxyurea \| CHEMBL21334...) Show SMILES ONC(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA4				Bioorg Med Chem Lett 16: 4316-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.068 BindingDB Entry DOI: 10.7270/Q2HX1C9J
Università degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 5A, mitochondrial (Homo sapiens (Human))	BDBM50188774 (1-(3,4-dichlorophenyl)-3-hydroxyurea \| CHEMBL21334...) Show SMILES ONC(=O)Nc1ccc(Cl)c(Cl)c1 Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	910	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA5a				Bioorg Med Chem Lett 16: 4316-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.068 BindingDB Entry DOI: 10.7270/Q2HX1C9J
Università degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50017811 (CHEMBL467 \| HU \| US10155732, Compound HU \| hydroxy...) Show SMILES NC(=O)NO Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA9				Bioorg Med Chem Lett 16: 4316-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.068 BindingDB Entry DOI: 10.7270/Q2HX1C9J
Università degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50017811 (CHEMBL467 \| HU \| US10155732, Compound HU \| hydroxy...) Show SMILES NC(=O)NO Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	PDB Article PubMed	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA2				Bioorg Med Chem Lett 16: 4316-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.068 BindingDB Entry DOI: 10.7270/Q2HX1C9J
Università degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 5A, mitochondrial (Homo sapiens (Human))	BDBM50017811 (CHEMBL467 \| HU \| US10155732, Compound HU \| hydroxy...) Show SMILES NC(=O)NO Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA5a				Bioorg Med Chem Lett 16: 4316-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.068 BindingDB Entry DOI: 10.7270/Q2HX1C9J
Università degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50017811 (CHEMBL467 \| HU \| US10155732, Compound HU \| hydroxy...) Show SMILES NC(=O)NO Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	1.13E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA4				Bioorg Med Chem Lett 16: 4316-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.068 BindingDB Entry DOI: 10.7270/Q2HX1C9J
Università degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50099857 (ACETOHYDROXAMIC ACID (AHA) \| AHA \| Acethydroxamsae...) Show SMILES CC(=O)NO Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	4.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human CA2				Bioorg Med Chem Lett 16: 4316-20 (2006) Article DOI: 10.1016/j.bmcl.2006.05.068 BindingDB Entry DOI: 10.7270/Q2HX1C9J
Università degli Studi di Firenze Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)

* indicates data uncertainty>20%