Affinity Data by PubMed id=16793264

PubMed code 16793264

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50189939 (5-(4-amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-6-hydrox...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to f7a/TF complex				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50189938 (2-{5-(4-amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-3'-[3...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to f7a/TF complex				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM14863 (({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to f7a/TF complex				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50189941 (2-{5-(4-amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-6-hyd...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to f7a/TF complex				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50189942 (4-{3-[3'-(4-amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-5...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to f7a/TF complex				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50189937 ((S)-N-[3'-(4-amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to f7a/TF complex				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor VII/Tissue factor (Homo sapiens (Human))	BDBM50189940 ((S)-2-hydroxy-N-[2'-hydroxy-3'-(1H-pyrrolo[3,2-c]p...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to f7a/TF complex				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM14863 (({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to f10a				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50189940 ((S)-2-hydroxy-N-[2'-hydroxy-3'-(1H-pyrrolo[3,2-c]p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to f10a				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50189937 ((S)-N-[3'-(4-amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to f10a				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM14863 (({3-[3-(5-carbamimidoyl-1H-1,3-benzodiazol-2-yl)-2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to thrombin				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50189937 ((S)-N-[3'-(4-amino-1H-pyrrolo[3,2-c]pyridin-2-yl)-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to thrombin				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50189940 ((S)-2-hydroxy-N-[2'-hydroxy-3'-(1H-pyrrolo[3,2-c]p...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Celera Genomics Curated by ChEMBL					Assay Description Binding affinity to thrombin				Bioorg Med Chem Lett 16: 4567-70 (2006) Article DOI: 10.1016/j.bmcl.2006.06.016 BindingDB Entry DOI: 10.7270/Q2NG4Q67
Celera Genomics Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%