Affinity Data by PubMed id=1680195

PubMed code 1680195

Found 23 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity towards Dopamine receptor D2 in rat striatal membrane by using [3H]spiperone as radioligand				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007571 (6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]qui...) Show SMILES CCCN1CCC=C2C1CCc1sc(N)nc21 \|c:6\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity against dopamine receptor D1 in rat striatal membrane by using DA antagonist [3H]NPA				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007571 (6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]qui...) Show SMILES CCCN1CCC=C2C1CCc1sc(N)nc21 \|c:6\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity against dopamine receptor D1 in rat striatal membrane by using DA antagonist [3H]NPA				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007571 (6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]qui...) Show SMILES CCCN1CCC=C2C1CCc1sc(N)nc21 \|c:6\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity against dopamine receptor D1 in rat striatal membrane by using DA antagonist [3H]NPA				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	384	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity towards dopamine Dopamine receptor D1 in rat striatal membrane by using [3H]-SCH- 23390 as radiolig...				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007573 (4-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiaz...) Show SMILES CCCN1CCC=C(C1)c1csc(N)n1 \|c:6\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	574	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D2 in rat striatal membrane using [3H]spiperone				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007571 (6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]qui...) Show SMILES CCCN1CCC=C2C1CCc1sc(N)nc21 \|c:6\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity against dopamine receptor D1 in rat striatal membrane by using DA antagonist [3H]NPA				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007571 (6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]qui...) Show SMILES CCCN1CCC=C2C1CCc1sc(N)nc21 \|c:6\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D2 in rat striatal membrane using [3H]spiperone				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007570 (7-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]iso...) Show SMILES CCCN1CC=C2C(CCc3sc(N)nc23)C1 \|c:5\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D2 in rat striatal membrane using [3H]spiperone				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007575 (6-Propyl-4,5,5a,6,7,8,9,9a-octahydro-thiazolo[4,5-...) Show SMILES CCCN1CCCC2C1CCc1sc(N)nc21 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D2 in rat striatal membrane using [3H]spiperone				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007571 (6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]qui...) Show SMILES CCCN1CCC=C2C1CCc1sc(N)nc21 \|c:6\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D2 in rat striatal membrane using [3H]spiperone				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM81924 ((R)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3PPP(+/-)...) Show SMILES CCCN1CCCC(C1)c1cccc(O)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D2 in rat striatal membrane using [3H]spiperone				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007574 (7-Propyl-4,5,6,7,8,9-hexahydro-thiazolo[4,5-f]isoq...) Show SMILES CCCN1CCC2=C(CCc3sc(N)nc23)C1 \|t:6\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.43E+3	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D2 in rat striatal membrane using [3H]spiperone				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007575 (6-Propyl-4,5,5a,6,7,8,9,9a-octahydro-thiazolo[4,5-...) Show SMILES CCCN1CCCC2C1CCc1sc(N)nc21 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity towards dopamine receptor D1 in rat striatal membrane using [3H]-SCH- 23390				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007570 (7-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]iso...) Show SMILES CCCN1CC=C2C(CCc3sc(N)nc23)C1 \|c:5\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity towards dopamine receptor D1 in rat striatal membrane using [3H]-SCH- 23390				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007571 (6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]qui...) Show SMILES CCCN1CCC=C2C1CCc1sc(N)nc21 \|c:6\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity towards dopamine receptor D1 in rat striatal membrane using [3H]-SCH- 23390				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007571 (6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]qui...) Show SMILES CCCN1CCC=C2C1CCc1sc(N)nc21 \|c:6\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity towards dopamine receptor D1 in rat striatal membrane using [3H]-SCH- 23390				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007574 (7-Propyl-4,5,6,7,8,9-hexahydro-thiazolo[4,5-f]isoq...) Show SMILES CCCN1CCC2=C(CCc3sc(N)nc23)C1 \|t:6\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity towards dopamine receptor D1 in rat striatal membrane using [3H]-SCH- 23390				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007571 (6-Propyl-4,5,5a,6,7,8-hexahydro-thiazolo[4,5-f]qui...) Show SMILES CCCN1CCC=C2C1CCc1sc(N)nc21 \|c:6\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Compound was tested in vitro for binding affinity against dopamine receptor D1 in rat striatal membrane by using DA antagonist [3H]NPA				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007569 (8-Propyl-4,5,6,7,8,9-hexahydro-thiazolo[5,4-h]isoq...) Show SMILES CCCN1CCC2=C(C1)c1nc(N)sc1CC2 \|c:6\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity towards dopamine receptor D1 in rat striatal membrane using [3H]-SCH- 23390				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50007573 (4-(1-Propyl-1,2,5,6-tetrahydro-pyridin-3-yl)-thiaz...) Show SMILES CCCN1CCC=C(C1)c1csc(N)n1 \|c:6\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity towards dopamine receptor D1 in rat striatal membrane using [3H]-SCH- 23390				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM81924 ((R)-3-(1-Propyl-piperidin-3-yl)-phenol \| 3PPP(+/-)...) Show SMILES CCCN1CCCC(C1)c1cccc(O)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro binding affinity towards dopamine receptor D1 in rat striatal membrane using [3H]-SCH- 23390				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50007569 (8-Propyl-4,5,6,7,8,9-hexahydro-thiazolo[5,4-h]isoq...) Show SMILES CCCN1CCC2=C(C1)c1nc(N)sc1CC2 \|c:6\| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.56E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D2 in rat striatal membrane using [3H]spiperone				J Med Chem 34: 2736-46 (1991) BindingDB Entry DOI: 10.7270/Q2V125FC
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%