Found 6 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Transient receptor potential cation channel subfamily V member 1
(Homo sapiens (Human)) | BDBM50189987
(6-phenyl-N-(quinolin-7-yl)nicotinamide | CHEMBL213...)Show InChI InChI=1S/C21H15N3O/c25-21(24-18-10-8-16-7-4-12-22-20(16)13-18)17-9-11-19(23-14-17)15-5-2-1-3-6-15/h1-14H,(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.90 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Antagonist activity against human TRPV1 assessed as inhibition of acid-induced calcium influx by FLIPR assay |
Bioorg Med Chem Lett 16: 4533-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.026
BindingDB Entry DOI: 10.7270/Q20R9P1B |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50189987
(6-phenyl-N-(quinolin-7-yl)nicotinamide | CHEMBL213...)Show InChI InChI=1S/C21H15N3O/c25-21(24-18-10-8-16-7-4-12-22-20(16)13-18)17-9-11-19(23-14-17)15-5-2-1-3-6-15/h1-14H,(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibition of cytochrome P450 2C9 |
Bioorg Med Chem Lett 16: 4533-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.026
BindingDB Entry DOI: 10.7270/Q20R9P1B |
More data for this
Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50189987
(6-phenyl-N-(quinolin-7-yl)nicotinamide | CHEMBL213...)Show InChI InChI=1S/C21H15N3O/c25-21(24-18-10-8-16-7-4-12-22-20(16)13-18)17-9-11-19(23-14-17)15-5-2-1-3-6-15/h1-14H,(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibition of cytochrome P450 3A4 |
Bioorg Med Chem Lett 16: 4533-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.026
BindingDB Entry DOI: 10.7270/Q20R9P1B |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50189987
(6-phenyl-N-(quinolin-7-yl)nicotinamide | CHEMBL213...)Show InChI InChI=1S/C21H15N3O/c25-21(24-18-10-8-16-7-4-12-22-20(16)13-18)17-9-11-19(23-14-17)15-5-2-1-3-6-15/h1-14H,(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibition of cytochrome P450 2C19 |
Bioorg Med Chem Lett 16: 4533-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.026
BindingDB Entry DOI: 10.7270/Q20R9P1B |
More data for this
Ligand-Target Pair | |
Cytochrome P450 1A2
(Homo sapiens (Human)) | BDBM50189987
(6-phenyl-N-(quinolin-7-yl)nicotinamide | CHEMBL213...)Show InChI InChI=1S/C21H15N3O/c25-21(24-18-10-8-16-7-4-12-22-20(16)13-18)17-9-11-19(23-14-17)15-5-2-1-3-6-15/h1-14H,(H,24,25) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibition of cytochrome P450 1A2 |
Bioorg Med Chem Lett 16: 4533-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.026
BindingDB Entry DOI: 10.7270/Q20R9P1B |
More data for this
Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50189987
(6-phenyl-N-(quinolin-7-yl)nicotinamide | CHEMBL213...)Show InChI InChI=1S/C21H15N3O/c25-21(24-18-10-8-16-7-4-12-22-20(16)13-18)17-9-11-19(23-14-17)15-5-2-1-3-6-15/h1-14H,(H,24,25) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline
Curated by ChEMBL
| Assay Description
Inhibition of cytochrome P450 2D6 |
Bioorg Med Chem Lett 16: 4533-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.026
BindingDB Entry DOI: 10.7270/Q20R9P1B |
More data for this
Ligand-Target Pair | |
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