Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Heme oxygenase 1 (Rattus norvegicus (rat)) | BDBM31768 (CHEMBL295698 | Ketoconazole | Nizoral | Panfungol) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 1 (Rattus norvegicus (rat)) | BDBM31769 (Terconazole | cid_5404) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 1 (Rattus norvegicus (rat)) | BDBM31770 (Exelderm | Sulconazole Nitrate | cid_65495 | sulco...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 2 (Rattus norvegicus (rat)) | BDBM31769 (Terconazole | cid_5404) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 1 (Rattus norvegicus (rat)) | BDBM31771 (Isoconazole | cid_3760) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 1 (Rattus norvegicus (rat)) | BDBM31772 (1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dichlorophenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.80E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 2 (Rattus norvegicus (rat)) | BDBM31768 (CHEMBL295698 | Ketoconazole | Nizoral | Panfungol) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 1 (Rattus norvegicus (rat)) | BDBM31773 (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 2 (Rattus norvegicus (rat)) | BDBM31771 (Isoconazole | cid_3760) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.26E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 1 (Rattus norvegicus (rat)) | BDBM31774 (CHEMBL104 | Canesten | Clotrimazole | Lotrimin | M...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 2 (Rattus norvegicus (rat)) | BDBM31772 (1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dichlorophenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.50E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 2 (Rattus norvegicus (rat)) | BDBM31773 (ECONAZOLE | Econazole nitrate | Gyno-pevaryl | Pev...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 2 (Rattus norvegicus (rat)) | BDBM31770 (Exelderm | Sulconazole Nitrate | cid_65495 | sulco...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 1 (Rattus norvegicus (rat)) | BDBM25817 (2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 1 (Rattus norvegicus (rat)) | BDBM31775 (Amudane | Fulvicin | Grisefuline | Griseofulvin) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 2 (Rattus norvegicus (rat)) | BDBM31775 (Amudane | Fulvicin | Grisefuline | Griseofulvin) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 2 (Rattus norvegicus (rat)) | BDBM31774 (CHEMBL104 | Canesten | Clotrimazole | Lotrimin | M...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Heme oxygenase 2 (Rattus norvegicus (rat)) | BDBM25817 (2-(2,4-difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | 7.4 | 37 |
Queen's University | Assay Description HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem... | J Pharmacol Exp Ther 319: 277-84 (2006) Article DOI: 10.1124/jpet.106.102699 BindingDB Entry DOI: 10.7270/Q2HH6HD9 | |||||||||||
More data for this Ligand-Target Pair |