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PubMed code 16821788

Compile data set for download or QSAR
Found 6 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Oligopeptide transporter, kidney isoform


(Rattus norvegicus)
BDBM50190616
PNG
((S)-2-((S)-2-benzamido-3-phenylpropanamido)propano...)
Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C19H20N2O4/c1-13(19(24)25)20-18(23)16(12-14-8-4-2-5-9-14)21-17(22)15-10-6-3-7-11-15/h2-11,13,16H,12H2,1H3,(H,20,23)(H,21,22)(H,24,25)/t13-,16-/m0/s1
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PubMed
3.70E+3n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Displacement of [14C]Gly-Sar from rat PEPT2 in SKPT0193 C1.2 cells


J Med Chem 49: 4286-96 (2006)


Article DOI: 10.1021/jm0601811
More data for this
Ligand-Target Pair
Oligopeptide transporter, kidney isoform


(Rattus norvegicus)
BDBM50169160
PNG
((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)pr...)
Show SMILES C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(O)=O
Show InChI InChI=1S/C14H17N3O3/c1-8(14(19)20)17-13(18)11(15)6-9-7-16-12-5-3-2-4-10(9)12/h2-5,7-8,11,16H,6,15H2,1H3,(H,17,18)(H,19,20)/t8-,11-/m0/s1
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4.00E+3n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Displacement of [14C]Gly-Sar from rat PEPT2 in SKPT0193 C1.2 cells


J Med Chem 49: 4286-96 (2006)


Article DOI: 10.1021/jm0601811
More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens (Human))
BDBM50190616
PNG
((S)-2-((S)-2-benzamido-3-phenylpropanamido)propano...)
Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1)C(O)=O
Show InChI InChI=1S/C19H20N2O4/c1-13(19(24)25)20-18(23)16(12-14-8-4-2-5-9-14)21-17(22)15-10-6-3-7-11-15/h2-11,13,16H,12H2,1H3,(H,20,23)(H,21,22)(H,24,25)/t13-,16-/m0/s1
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2.00E+4n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Displacement of [14C]Gly-Sar from human PEPT1 in Caco2 cells


J Med Chem 49: 4286-96 (2006)


Article DOI: 10.1021/jm0601811
More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens (Human))
BDBM50169169
PNG
((2S)-2-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]p...)
Show SMILES CC(C)C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Show InChI InChI=1S/C15H30N6O4/c1-8(2)7-10(16)13(23)20-9(3)12(22)21-11(14(24)25)5-4-6-19-15(17)18/h8-11H,4-7,16H2,1-3H3,(H,20,23)(H,21,22)(H,24,25)(H4,17,18,19)/t9-,10-,11-/m0/s1
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1.00E+5n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Displacement of [14C]Gly-Sar from human PEPT1 in Caco2 cells


J Med Chem 49: 4286-96 (2006)


Article DOI: 10.1021/jm0601811
More data for this
Ligand-Target Pair
Oligopeptide transporter small intestine isoform


(Homo sapiens (Human))
BDBM50169160
PNG
((S)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)pr...)
Show SMILES C[C@H](NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(O)=O
Show InChI InChI=1S/C14H17N3O3/c1-8(14(19)20)17-13(18)11(15)6-9-7-16-12-5-3-2-4-10(9)12/h2-5,7-8,11,16H,6,15H2,1H3,(H,17,18)(H,19,20)/t8-,11-/m0/s1
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PubMed
1.60E+5n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Displacement of [14C]Gly-Sar from human PEPT1 in Caco2 cells


J Med Chem 49: 4286-96 (2006)


Article DOI: 10.1021/jm0601811
More data for this
Ligand-Target Pair
Oligopeptide transporter, kidney isoform


(Rattus norvegicus)
BDBM50169169
PNG
((2S)-2-[(2S)-2-[(2S)-2-amino-4-methylpentanamido]p...)
Show SMILES CC(C)C[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
Show InChI InChI=1S/C15H30N6O4/c1-8(2)7-10(16)13(23)20-9(3)12(22)21-11(14(24)25)5-4-6-19-15(17)18/h8-11H,4-7,16H2,1-3H3,(H,20,23)(H,21,22)(H,24,25)(H4,17,18,19)/t9-,10-,11-/m0/s1
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1.20E+6n/an/an/an/an/an/an/an/a



Martin-Luther-University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Displacement of [14C]Gly-Sar from rat PEPT2 in SKPT0193 C1.2 cells


J Med Chem 49: 4286-96 (2006)


Article DOI: 10.1021/jm0601811
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%