Affinity Data by PubMed id=16843659

PubMed code 16843659

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cytochrome P450 1A2 (Homo sapiens (Human))	BDBM50191163 (1-(2-(benzyloxy)-5-bromobenzyl)-5-methyl-1H-pyrazo...) Show SMILES Cc1cc(nn1Cc1cc(Br)ccc1OCc1ccccc1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CYP450 1A2				Bioorg Med Chem Lett 16: 4767-71 (2006) Article DOI: 10.1016/j.bmcl.2006.06.086 BindingDB Entry DOI: 10.7270/Q2MC8ZN4
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50191163 (1-(2-(benzyloxy)-5-bromobenzyl)-5-methyl-1H-pyrazo...) Show SMILES Cc1cc(nn1Cc1cc(Br)ccc1OCc1ccccc1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CYP450 2C19				Bioorg Med Chem Lett 16: 4767-71 (2006) Article DOI: 10.1016/j.bmcl.2006.06.086 BindingDB Entry DOI: 10.7270/Q2MC8ZN4
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50191163 (1-(2-(benzyloxy)-5-bromobenzyl)-5-methyl-1H-pyrazo...) Show SMILES Cc1cc(nn1Cc1cc(Br)ccc1OCc1ccccc1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CYP450 3A4				Bioorg Med Chem Lett 16: 4767-71 (2006) Article DOI: 10.1016/j.bmcl.2006.06.086 BindingDB Entry DOI: 10.7270/Q2MC8ZN4
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50191163 (1-(2-(benzyloxy)-5-bromobenzyl)-5-methyl-1H-pyrazo...) Show SMILES Cc1cc(nn1Cc1cc(Br)ccc1OCc1ccccc1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CYP450 2C9				Bioorg Med Chem Lett 16: 4767-71 (2006) Article DOI: 10.1016/j.bmcl.2006.06.086 BindingDB Entry DOI: 10.7270/Q2MC8ZN4
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50191163 (1-(2-(benzyloxy)-5-bromobenzyl)-5-methyl-1H-pyrazo...) Show SMILES Cc1cc(nn1Cc1cc(Br)ccc1OCc1ccccc1)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of CYP450 2D6				Bioorg Med Chem Lett 16: 4767-71 (2006) Article DOI: 10.1016/j.bmcl.2006.06.086 BindingDB Entry DOI: 10.7270/Q2MC8ZN4
GlaxoSmithKline Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%