Found 21 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191795
(CHEMBL386256 | N-3-(4-bromophenyl)propyl imidazole)Show InChI InChI=1S/C12H13BrN2/c13-12-5-3-11(4-6-12)2-1-8-15-9-7-14-10-15/h3-7,9-10H,1-2,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191792
(1-(3-(4-chlorophenyl)propyl)-1H-imidazole | CHEMBL...)Show InChI InChI=1S/C12H13ClN2/c13-12-5-3-11(4-6-12)2-1-8-15-9-7-14-10-15/h3-7,9-10H,1-2,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM31768
(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)Show SMILES CC(=O)N1CCN(CC1)c1ccc(OC[C@@H]2CO[C@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 |r| Show InChI InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191794
(1-(3-(4-fluorophenyl)propyl)-1H-imidazole | CHEMBL...)Show InChI InChI=1S/C12H13FN2/c13-12-5-3-11(4-6-12)2-1-8-15-9-7-14-10-15/h3-7,9-10H,1-2,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188088
(1-(4-bromobenzyl)-1H-imidazole | CHEMBL211207)Show InChI InChI=1S/C10H9BrN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191795
(CHEMBL386256 | N-3-(4-bromophenyl)propyl imidazole)Show InChI InChI=1S/C12H13BrN2/c13-12-5-3-11(4-6-12)2-1-8-15-9-7-14-10-15/h3-7,9-10H,1-2,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM31768
(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)Show SMILES CC(=O)N1CCN(CC1)c1ccc(OC[C@@H]2CO[C@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 |r| Show InChI InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3/t23-,26-/m1/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188097
(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)Show InChI InChI=1S/C10H9ClN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191792
(1-(3-(4-chlorophenyl)propyl)-1H-imidazole | CHEMBL...)Show InChI InChI=1S/C12H13ClN2/c13-12-5-3-11(4-6-12)2-1-8-15-9-7-14-10-15/h3-7,9-10H,1-2,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 5.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191796
(1-(3-phenylpropyl)-1H-imidazole | CHEMBL380271)Show InChI InChI=1S/C12H14N2/c1-2-5-12(6-3-1)7-4-9-14-10-8-13-11-14/h1-3,5-6,8,10-11H,4,7,9H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188085
(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)Show InChI InChI=1S/C10H9FN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188088
(1-(4-bromobenzyl)-1H-imidazole | CHEMBL211207)Show InChI InChI=1S/C10H9BrN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.66E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191794
(1-(3-(4-fluorophenyl)propyl)-1H-imidazole | CHEMBL...)Show InChI InChI=1S/C12H13FN2/c13-12-5-3-11(4-6-12)2-1-8-15-9-7-14-10-15/h3-7,9-10H,1-2,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.78E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188097
(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)Show InChI InChI=1S/C10H9ClN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.98E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191797
(1-(4-bromophenethyl)-1H-imidazole | CHEMBL215320)Show InChI InChI=1S/C11H11BrN2/c12-11-3-1-10(2-4-11)5-7-14-8-6-13-9-14/h1-4,6,8-9H,5,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191796
(1-(3-phenylpropyl)-1H-imidazole | CHEMBL380271)Show InChI InChI=1S/C12H14N2/c1-2-5-12(6-3-1)7-4-9-14-10-8-13-11-14/h1-3,5-6,8,10-11H,4,7,9H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191793
(1-(4-chlorophenethyl)-1H-imidazole | CHEMBL379290)Show InChI InChI=1S/C11H11ClN2/c12-11-3-1-10(2-4-11)5-7-14-8-6-13-9-14/h1-4,6,8-9H,5,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.96E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM7887
(1-Benzylimidazole (BI) | 1-benzyl-1H-imidazole | 1...)Show InChI InChI=1S/C10H10N2/c1-2-4-10(5-3-1)8-12-7-6-11-9-12/h1-7,9H,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 5.09E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17,20 lyase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50188085
(1-(4-Fluorobenzyl)-1H-imidazole | CHEMBL377770)Show InChI InChI=1S/C10H9FN2/c11-10-3-1-9(2-4-10)7-13-6-5-12-8-13/h1-6,8H,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 9.65E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM50191791
(1-(4-fluorophenethyl)-1H-imidazole | CHEMBL215425)Show InChI InChI=1S/C11H11FN2/c12-11-3-1-10(2-4-11)5-7-14-8-6-13-9-14/h1-4,6,8-9H,5,7H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |
Steroid 17-alpha-hydroxylase/17,20 lyase
(Rattus norvegicus (Rat)) | BDBM7887
(1-Benzylimidazole (BI) | 1-benzyl-1H-imidazole | 1...)Show InChI InChI=1S/C10H10N2/c1-2-4-10(5-3-1)8-12-7-6-11-9-12/h1-7,9H,8H2 | KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.54E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Kingston University
Curated by ChEMBL
| Assay Description Inhibition of rat testis 17alpha-hydroxylase component of P450-17alpha |
Bioorg Med Chem Lett 16: 4752-6 (2006)
Article DOI: 10.1016/j.bmcl.2006.06.092 BindingDB Entry DOI: 10.7270/Q2P55N43 |
More data for this Ligand-Target Pair | |