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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lethal factor (Bacillus anthracis) | BDBM12008 ((1R,3S,4R,5R,6S)-4-{[(2R,3R,4R,5S,6R)-6-(aminometh...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet  | PC cid PC sid UniChem Similars | Article PubMed | 500 | -35.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM19 ((2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(2R,3...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 500 | -35.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM12005 ((2R,3R,4R,5S,6R)-2-{[(1R,2R,3S,4R,6S)-4-amino-6-ca...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 700 | -34.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM11997 ((1R,3S,4R,5R,6S)-4-{[(2R,3R,4R,5S,6R)-3-carbamimid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 700 | -34.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM12012 ((1R,3S,4R,5R,6S)-4-{[(2R,3R,4R,5R,6R)-3-carbamimid...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.50E+3 | -32.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM12010 ((2R,3R,4R,5S,6R)-2-{[(1R,2R,3S,4R,6S)-6-amino-4-ca...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.10E+3 | -31.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM11998 ((1R,2S,3R,4R,5S)-5-amino-4-{[(2R,3R,4R,5S,6R)-3-am...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 5.00E+3 | -30.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM11999 ((1S,2R,3R,4S,5R)-5-amino-2-{[(2R,3R,4R,5S,6R)-3-am...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 5.20E+3 | -29.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM12003 ((2R,3R,4R,5S,6R)-2-{[(1R,2R,3S,4R,6S)-6-amino-4-ca...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 5.30E+3 | -29.8 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM12002 ((1R,3S,4R,5R,6S)-4-{[(2R,3R,4R,5S,6R)-3-amino-6-(a...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 5.60E+3 | -29.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM12007 ((2R,3R,4R,5S,6R)-6-(carbamimidamidomethyl)-2-{[(1R...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 7.70E+3 | -28.9 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM12009 ((1R,3S,4R,5R,6S)-4-{[(2R,3R,4R,5S,6R)-3-amino-6-(c...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 8.70E+3 | -28.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM12006 ((1S,2R,3R,4S,5R)-5-amino-2-{[(2R,3R,4R,5S,6R)-3-am...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 8.80E+3 | -28.6 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM12011 ((2R,3R,4R,5S,6R)-2-{[(1R,2R,3S,4R,6S)-4-amino-6-ca...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 9.20E+3 | -28.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM12004 ((1R,2S,3R,4R,5S)-5-amino-4-{[(2R,3R,4R,5S,6R)-3-am...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.02E+4 | -28.2 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM12000 ((2R,3R,4R,5S,6R)-6-(aminomethyl)-2-{[(1R,2R,3S,4R,...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.09E+4 | -28.0 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM12001 (3-{[(2R,3S,4R,5R,6R)-5-amino-6-{[(1R,2R,3S,4R,6S)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 2.43E+4 | -26.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Lethal factor (Bacillus anthracis) | BDBM8580 ((2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(1R,2...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 4.29E+4 | -24.7 | n/a | n/a | n/a | n/a | n/a | 7.4 | 22 |
Hawaii Biotech Inc. | Assay Description The enzymatic reaction started by the addition fluorogenic peptide substrate, MAPKKide to the buffer containing LF and inhibitor compound. Cleavage o... | Bioorg Med Chem Lett 16: 5183-9 (2006) Article DOI: 10.1016/j.bmcl.2006.07.005 BindingDB Entry DOI: 10.7270/Q2VQ30WD | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
