Found 42 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Synaptic vesicular amine transporter
(Rattus norvegicus (Rat)) | BDBM50192902
(2-ethyl-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-he...)Show InChI InChI=1S/C21H33NO3/c1-6-21(23)12-18-17-11-20(25-5)19(24-4)10-15(17)7-8-22(18)13-16(21)9-14(2)3/h10-11,14,16,18,23H,6-9,12-13H2,1-5H3 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 28 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50192903
(8R-hydroxylobel-9-ene | CHEMBL425617)Show SMILES CN1[C@@H](C[C@@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50080826
((S)-2-[(2S,6R)-1-Methyl-6-((E)-styryl)-piperidin-2...)Show SMILES CN1[C@H](C[C@H](O)c2ccccc2)CCC[C@@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22+/m1/s1 | Reactome pathway
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50080821
((R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl...)Show SMILES CN1[C@H](CCc2ccccc2)CCC[C@@H]1C[C@@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22+/m0/s1 | PDB
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| Article
PubMed
| 150 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50192907
(10R-hydroxylobel-7-ene | CHEMBL217815)Show SMILES CN1[C@H](C[C@@H](O)c2ccccc2)CCC[C@@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m1/s1 | Reactome pathway
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PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 290 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50192904
(10R-hydroxylobelane | CHEMBL213148)Show SMILES CN1[C@@H](CCc2ccccc2)CCC[C@H]1C[C@@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22-/m1/s1 | Reactome pathway
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PC cid
PC sid
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| Article
PubMed
| 570 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Synaptic vesicular amine transporter
(Rattus norvegicus (Rat)) | BDBM50192907
(10R-hydroxylobel-7-ene | CHEMBL217815)Show SMILES CN1[C@H](C[C@@H](O)c2ccccc2)CCC[C@@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50192903
(8R-hydroxylobel-9-ene | CHEMBL425617)Show SMILES CN1[C@@H](C[C@@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22+/m0/s1 | Reactome pathway
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PC sid
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| Article
PubMed
| 860 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50192906
(8S-hydroxylobel-9-ene | CHEMBL213613)Show SMILES CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m0/s1 | Reactome pathway
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PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| 960 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50080821
((R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl...)Show SMILES CN1[C@H](CCc2ccccc2)CCC[C@@H]1C[C@@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22+/m0/s1 | PDB
Reactome pathway
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PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]MLA binding to alpha7 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50192905
(8S-hydroxylobelane | CHEMBL377539)Show SMILES CN1[C@H](CCc2ccccc2)CCC[C@@H]1C[C@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22-/m0/s1 | Reactome pathway
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| Article
PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50080814
((S)-2-((2S,6R)-1-Methyl-6-phenethyl-piperidin-2-yl...)Show SMILES CN1[C@@H](CCc2ccccc2)CCC[C@H]1C[C@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22+/m1/s1 | Reactome pathway
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PubMed
| 1.39E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50192903
(8R-hydroxylobel-9-ene | CHEMBL425617)Show SMILES CN1[C@@H](C[C@@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22+/m0/s1 | PDB
Reactome pathway
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]MLA binding to alpha7 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50080814
((S)-2-((2S,6R)-1-Methyl-6-phenethyl-piperidin-2-yl...)Show SMILES CN1[C@@H](CCc2ccccc2)CCC[C@H]1C[C@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22+/m1/s1 | PDB
MMDB
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| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| 1.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NIC binding to alpha4beta2 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50080821
((R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl...)Show SMILES CN1[C@H](CCc2ccccc2)CCC[C@@H]1C[C@@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22+/m0/s1 | Reactome pathway
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| Article
PubMed
| 1.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DA uptake at DAT in rat striatal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Synaptic vesicular amine transporter
(Rattus norvegicus (Rat)) | BDBM50080821
((R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl...)Show SMILES CN1[C@H](CCc2ccccc2)CCC[C@@H]1C[C@@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22+/m0/s1 | PDB
UniProtKB/SwissProt
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| CHEMBL
PC cid
PC sid
UniChem
Patents
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| Article
PubMed
| 1.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50192905
(8S-hydroxylobelane | CHEMBL377539)Show SMILES CN1[C@H](CCc2ccccc2)CCC[C@@H]1C[C@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22-/m0/s1 | PDB
KEGG
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PC sid
UniChem
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PubMed
| 2.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50080821
((R)-2-((2R,6S)-1-Methyl-6-phenethyl-piperidin-2-yl...)Show SMILES CN1[C@H](CCc2ccccc2)CCC[C@@H]1C[C@@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22+/m0/s1 | PDB
MMDB
KEGG
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| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NIC binding to alpha4beta2 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Synaptic vesicular amine transporter
(Rattus norvegicus (Rat)) | BDBM50422013
(LOBELINE | Lobeline Hydrochloride)Show SMILES CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1CC(=O)c1ccccc1 Show InChI InChI=1S/C22H27NO2/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18/h2-7,9-12,19-21,24H,8,13-16H2,1H3/t19-,20+,21+/m1/s1 | PDB
UniProtKB/SwissProt
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| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Synaptic vesicular amine transporter
(Rattus norvegicus (Rat)) | BDBM50192905
(8S-hydroxylobelane | CHEMBL377539)Show SMILES CN1[C@H](CCc2ccccc2)CCC[C@@H]1C[C@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Synaptic vesicular amine transporter
(Rattus norvegicus (Rat)) | BDBM50080814
((S)-2-((2S,6R)-1-Methyl-6-phenethyl-piperidin-2-yl...)Show SMILES CN1[C@@H](CCc2ccccc2)CCC[C@H]1C[C@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.09E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50192906
(8S-hydroxylobel-9-ene | CHEMBL213613)Show SMILES CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50192903
(8R-hydroxylobel-9-ene | CHEMBL425617)Show SMILES CN1[C@@H](C[C@@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22+/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 4.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NIC binding to alpha4beta2 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50080814
((S)-2-((2S,6R)-1-Methyl-6-phenethyl-piperidin-2-yl...)Show SMILES CN1[C@@H](CCc2ccccc2)CCC[C@H]1C[C@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22+/m1/s1 | PDB
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PC sid
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| Article
PubMed
| 4.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Synaptic vesicular amine transporter
(Rattus norvegicus (Rat)) | BDBM50192903
(8R-hydroxylobel-9-ene | CHEMBL425617)Show SMILES CN1[C@@H](C[C@@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22+/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 5.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Synaptic vesicular amine transporter
(Rattus norvegicus (Rat)) | BDBM50192906
(8S-hydroxylobel-9-ene | CHEMBL213613)Show SMILES CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 6.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Synaptic vesicular amine transporter
(Rattus norvegicus (Rat)) | BDBM50080826
((S)-2-[(2S,6R)-1-Methyl-6-((E)-styryl)-piperidin-2...)Show SMILES CN1[C@H](C[C@H](O)c2ccccc2)CCC[C@@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 6.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Synaptic vesicular amine transporter
(Rattus norvegicus (Rat)) | BDBM50192904
(10R-hydroxylobelane | CHEMBL213148)Show SMILES CN1[C@@H](CCc2ccccc2)CCC[C@H]1C[C@@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]DTBZ binding to VMAT2 in rat synaptic vesicle membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50192904
(10R-hydroxylobelane | CHEMBL213148)Show SMILES CN1[C@@H](CCc2ccccc2)CCC[C@H]1C[C@@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50192907
(10R-hydroxylobel-7-ene | CHEMBL217815)Show SMILES CN1[C@H](C[C@@H](O)c2ccccc2)CCC[C@@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
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| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50080826
((S)-2-[(2S,6R)-1-Methyl-6-((E)-styryl)-piperidin-2...)Show SMILES CN1[C@H](C[C@H](O)c2ccccc2)CCC[C@@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22+/m1/s1 | PDB
MMDB
KEGG
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B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 9.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NIC binding to alpha4beta2 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Rattus norvegicus (rat)) | BDBM50080826
((S)-2-[(2S,6R)-1-Methyl-6-((E)-styryl)-piperidin-2...)Show SMILES CN1[C@H](C[C@H](O)c2ccccc2)CCC[C@@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22+/m1/s1 | PDB
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]5-HT uptake at SERT in rat hippocampal synaptosomes |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50192905
(8S-hydroxylobelane | CHEMBL377539)Show SMILES CN1[C@H](CCc2ccccc2)CCC[C@@H]1C[C@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22-/m0/s1 | PDB
MMDB
KEGG
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B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.36E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NIC binding to alpha4beta2 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50080814
((S)-2-((2S,6R)-1-Methyl-6-phenethyl-piperidin-2-yl...)Show SMILES CN1[C@@H](CCc2ccccc2)CCC[C@H]1C[C@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22+/m1/s1 | PDB
Reactome pathway
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| CHEMBL
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PC sid
UniChem
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| Article
PubMed
| 3.93E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]MLA binding to alpha7 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50192906
(8S-hydroxylobel-9-ene | CHEMBL213613)Show SMILES CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]MLA binding to alpha7 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50192907
(10R-hydroxylobel-7-ene | CHEMBL217815)Show SMILES CN1[C@H](C[C@@H](O)c2ccccc2)CCC[C@@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]MLA binding to alpha7 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50192904
(10R-hydroxylobelane | CHEMBL213148)Show SMILES CN1[C@@H](CCc2ccccc2)CCC[C@H]1C[C@@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NIC binding to alpha4beta2 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50080826
((S)-2-[(2S,6R)-1-Methyl-6-((E)-styryl)-piperidin-2...)Show SMILES CN1[C@H](C[C@H](O)c2ccccc2)CCC[C@@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]MLA binding to alpha7 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50192904
(10R-hydroxylobelane | CHEMBL213148)Show SMILES CN1[C@@H](CCc2ccccc2)CCC[C@H]1C[C@@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]MLA binding to alpha7 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50192907
(10R-hydroxylobel-7-ene | CHEMBL217815)Show SMILES CN1[C@H](C[C@@H](O)c2ccccc2)CCC[C@@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NIC binding to alpha4beta2 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-7
(Rattus norvegicus (Rat)) | BDBM50192905
(8S-hydroxylobelane | CHEMBL377539)Show SMILES CN1[C@H](CCc2ccccc2)CCC[C@@H]1C[C@H](O)c1ccccc1 Show InChI InChI=1S/C22H29NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,20-22,24H,8,13-17H2,1H3/t20-,21+,22-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]MLA binding to alpha7 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
Neuronal acetylcholine receptor subunit alpha-4/beta-2
(Rattus norvegicus (Rat)) | BDBM50192906
(8S-hydroxylobel-9-ene | CHEMBL213613)Show SMILES CN1[C@@H](C[C@H](O)c2ccccc2)CCC[C@H]1\C=C\c1ccccc1 Show InChI InChI=1S/C22H27NO/c1-23-20(16-15-18-9-4-2-5-10-18)13-8-14-21(23)17-22(24)19-11-6-3-7-12-19/h2-7,9-12,15-16,20-22,24H,8,13-14,17H2,1H3/b16-15+/t20-,21+,22-/m0/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Kentucky
Curated by ChEMBL
| Assay Description
Inhibition of [3H]NIC binding to alpha4beta2 nAChR in rat brain membrane |
Bioorg Med Chem Lett 16: 5018-21 (2006)
Article DOI: 10.1016/j.bmcl.2006.07.070
BindingDB Entry DOI: 10.7270/Q2513XTK |
More data for this
Ligand-Target Pair | |
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