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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM17750 (5-cyano-N-[5-(hydroxymethyl)-2-(4-methylpiperidin-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | 7.5 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description The full-length cFMS cytoplasmic domain (FMS.538-972.6His) was incubated with compound in reaction buffer. Control reactions were run in each plate. ... | J Biol Chem 282: 4094-101 (2007) Article DOI: 10.1074/jbc.M608183200 BindingDB Entry DOI: 10.7270/Q2HT2MKC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Macrophage colony-stimulating factor 1 receptor (Homo sapiens (Human)) | BDBM17751 (6-chloro-3-(3-methyl-1,2-oxazol-5-yl)-4-phenyl-1,2...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | DrugBank MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 160 | n/a | n/a | n/a | n/a | 7.5 | 22 |
Johnson & Johnson Pharmaceutical | Assay Description The full-length cFMS cytoplasmic domain (FMS.538-972.6His) was incubated with compound in reaction buffer. Control reactions were run in each plate. ... | J Biol Chem 282: 4094-101 (2007) Article DOI: 10.1074/jbc.M608183200 BindingDB Entry DOI: 10.7270/Q2HT2MKC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
