Affinity Data by PubMed id=17145787

PubMed code 17145787

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Liver carboxylesterase (Sus scrofa)	BDBM50022772 (CHEMBL1025 \| Diisopropoxyphosphoryl fluoride \| Dii...) Show SMILES CC(C)OP(F)(=O)OC(C)C Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of porcine liver carboxylesterase using [14C]GS7340 substrate				Antimicrob Agents Chemother 51: 543-50 (2007) Article DOI: 10.1128/AAC.00968-06 BindingDB Entry DOI: 10.7270/Q2ZG6RW5
Gilead Sciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal protective protein (Homo sapiens (Human))	BDBM50199883 (3,4‐Dichloroisocoumarin (2) \| 3,4-Dichloro-i...) Show SMILES Clc1oc(=O)c2ccccc2c1Cl Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant CatA using [14C]GS7340 substrate				Antimicrob Agents Chemother 51: 543-50 (2007) Article DOI: 10.1128/AAC.00968-06 BindingDB Entry DOI: 10.7270/Q2ZG6RW5
Gilead Sciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50199883 (3,4‐Dichloroisocoumarin (2) \| 3,4-Dichloro-i...) Show SMILES Clc1oc(=O)c2ccccc2c1Cl Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human leukocyte elastase using [14C]GS7340 substrate				Antimicrob Agents Chemother 51: 543-50 (2007) Article DOI: 10.1128/AAC.00968-06 BindingDB Entry DOI: 10.7270/Q2ZG6RW5
Gilead Sciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal protective protein (Homo sapiens (Human))	BDBM50022772 (CHEMBL1025 \| Diisopropoxyphosphoryl fluoride \| Dii...) Show SMILES CC(C)OP(F)(=O)OC(C)C Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant CatA using [14C]GS7340 substrate				Antimicrob Agents Chemother 51: 543-50 (2007) Article DOI: 10.1128/AAC.00968-06 BindingDB Entry DOI: 10.7270/Q2ZG6RW5
Gilead Sciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Liver carboxylesterase (Sus scrofa)	BDBM50199883 (3,4‐Dichloroisocoumarin (2) \| 3,4-Dichloro-i...) Show SMILES Clc1oc(=O)c2ccccc2c1Cl Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of porcine liver carboxylesterase using [14C]GS7340 substrate				Antimicrob Agents Chemother 51: 543-50 (2007) Article DOI: 10.1128/AAC.00968-06 BindingDB Entry DOI: 10.7270/Q2ZG6RW5
Gilead Sciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Liver carboxylesterase (Sus scrofa)	BDBM50157741 (CHEMBL374508 \| E-64 \| E64) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of porcine liver carboxylesterase using [14C]GS7340 substrate				Antimicrob Agents Chemother 51: 543-50 (2007) Article DOI: 10.1128/AAC.00968-06 BindingDB Entry DOI: 10.7270/Q2ZG6RW5
Gilead Sciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50157741 (CHEMBL374508 \| E-64 \| E64) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human leukocyte elastase using [14C]GS7340 substrate				Antimicrob Agents Chemother 51: 543-50 (2007) Article DOI: 10.1128/AAC.00968-06 BindingDB Entry DOI: 10.7270/Q2ZG6RW5
Gilead Sciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Lysosomal protective protein (Homo sapiens (Human))	BDBM50157741 (CHEMBL374508 \| E-64 \| E64) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. Curated by ChEMBL					Assay Description Inhibition of recombinant CatA using [14C]GS7340 substrate				Antimicrob Agents Chemother 51: 543-50 (2007) Article DOI: 10.1128/AAC.00968-06 BindingDB Entry DOI: 10.7270/Q2ZG6RW5
Gilead Sciences, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%