Affinity Data by PubMed id=17154492

PubMed code 17154492

Found 5 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM3032 (CHEMBL1204168 \| CHEMBL29197 \| N-(3-bromophenyl)-6,...) Show SMILES COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of EGFR tyrosine kinase activity				J Med Chem 49: 6642-5 (2006) Article DOI: 10.1021/jm0608762 BindingDB Entry DOI: 10.7270/Q28P605H
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM4567 (4-anilinoquinazoline deriv. 2 \| BMC163482 Compound...) Show SMILES Brc1cccc(Nc2ncnc3ccc(NC(=O)C=C)cc23)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of EGFR tyrosine kinase activity				J Med Chem 49: 6642-5 (2006) Article DOI: 10.1021/jm0608762 BindingDB Entry DOI: 10.7270/Q28P605H
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50200279 (CHEMBL217536 \| N-(4-(3-bromophenylamino)quinazolin...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of EGFR tyrosine kinase activity				J Med Chem 49: 6642-5 (2006) Article DOI: 10.1021/jm0608762 BindingDB Entry DOI: 10.7270/Q28P605H
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50200280 (CHEMBL217825 \| N-(4-(3-bromophenylamino)quinazolin...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of EGFR tyrosine kinase activity				J Med Chem 49: 6642-5 (2006) Article DOI: 10.1021/jm0608762 BindingDB Entry DOI: 10.7270/Q28P605H
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50200278 (CHEMBL450944 \| N-(4-(3-bromophenylamino)quinazolin...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of EGFR tyrosine kinase activity				J Med Chem 49: 6642-5 (2006) Article DOI: 10.1021/jm0608762 BindingDB Entry DOI: 10.7270/Q28P605H
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%