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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alpha-2A adrenergic receptor [16-465] (Rattus norvegicus (rat)) | BDBM50201046 (5-{3-[4-(3-chlorophenyl)hexahydro-1-pyrazinyl]prop...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem | Article PubMed | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Binding affinity to adrenergic alpha2A receptor in Sprague-Dawley rat cortical membranes | J Med Chem 49: 7826-35 (2006) Article DOI: 10.1021/jm060743g BindingDB Entry DOI: 10.7270/Q29K49W5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Transporter (Rattus norvegicus) | BDBM50201046 (5-{3-[4-(3-chlorophenyl)hexahydro-1-pyrazinyl]prop...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL | Assay Description Inhibition of [3H]noradrenaline uptake in Sprague-Dawley rat brain synaptosomes | J Med Chem 49: 7826-35 (2006) Article DOI: 10.1021/jm060743g BindingDB Entry DOI: 10.7270/Q29K49W5 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
