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PubMed code 17234412

Compile data set for download or QSAR
Found 1 hit of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM50202760
PNG
(4-(3-(1H-benzo[d]imidazol-2-yl)-1H-pyrazolo[3,4-b]...)
Show SMILES c1ccc2[nH]c(nc2c1)-c1n[nH]c2ncc(cc12)-c1cncc2ccccc12
Show InChI InChI=1S/C22H14N6/c1-2-6-15-13(5-1)10-23-12-17(15)14-9-16-20(27-28-21(16)24-11-14)22-25-18-7-3-4-8-19(18)26-22/h1-12H,(H,25,26)(H,24,27,28)
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Article
PubMed
n/an/a 1.46E+3n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research & Development L. L. C.

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2


Bioorg Med Chem Lett 17: 1243-5 (2007)


Article DOI: 10.1016/j.bmcl.2006.12.031
BindingDB Entry DOI: 10.7270/Q20Z72Z9
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%