Found 3 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem Lett 17: 1558-61 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.117
BindingDB Entry DOI: 10.7270/Q2F18ZCJ |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19131
(CHEMBL419758 | JMC505425 Compound 7 | N-(4-phenyl-...)Show InChI InChI=1S/C16H20N2OS2/c19-15(10-6-1-2-7-11-20)18-16-17-14(12-21-16)13-8-4-3-5-9-13/h3-5,8-9,12,20H,1-2,6-7,10-11H2,(H,17,18,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem Lett 17: 1558-61 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.117
BindingDB Entry DOI: 10.7270/Q2F18ZCJ |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50203548
(CHEMBL384522 | S-7-oxo-7-(4-phenylthiazol-2-ylamin...)Show SMILES CC(Cc1ccccc1)C(=O)SCCCCCCC(=O)Nc1nc(cs1)-c1ccccc1 Show InChI InChI=1S/C26H30N2O2S2/c1-20(18-21-12-6-4-7-13-21)25(30)31-17-11-3-2-10-16-24(29)28-26-27-23(19-32-26)22-14-8-5-9-15-22/h4-9,12-15,19-20H,2-3,10-11,16-18H2,1H3,(H,27,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Nagoya City University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem Lett 17: 1558-61 (2007)
Article DOI: 10.1016/j.bmcl.2006.12.117
BindingDB Entry DOI: 10.7270/Q2F18ZCJ |
More data for this
Ligand-Target Pair | |
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