Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plasminogen activator inhibitor 1 (Homo sapiens (Human)) | BDBM50149275 (2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Medical School Curated by ChEMBL | Assay Description Inhibition of human glycosylated PAI1 using urokinase type plasminogen activator substrate by direct chromogenic assay | J Biol Chem 282: 9288-96 (2007) Article DOI: 10.1074/jbc.M611642200 BindingDB Entry DOI: 10.7270/Q2FF3S51 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen activator inhibitor 1 (Homo sapiens (Human)) | BDBM50149275 (2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Medical School Curated by ChEMBL | Assay Description Inhibition of human non-glycosylated PAI1 using urokinase type plasminogen activator substrate by direct chromogenic assay | J Biol Chem 282: 9288-96 (2007) Article DOI: 10.1074/jbc.M611642200 BindingDB Entry DOI: 10.7270/Q2FF3S51 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen activator inhibitor 1 (Homo sapiens (Human)) | BDBM50149275 (2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.14E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Medical School Curated by ChEMBL | Assay Description Inhibition of human non-glycosylated PAI1 using tissue type plasminogen activator substrate by direct chromogenic assay | J Biol Chem 282: 9288-96 (2007) Article DOI: 10.1074/jbc.M611642200 BindingDB Entry DOI: 10.7270/Q2FF3S51 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen activator inhibitor 1 (Homo sapiens (Human)) | BDBM50149275 (2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.23E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Medical School Curated by ChEMBL | Assay Description Inhibition of human glycosylated PAI1 using tissue type plasminogen activator substrate by direct chromogenic assay | J Biol Chem 282: 9288-96 (2007) Article DOI: 10.1074/jbc.M611642200 BindingDB Entry DOI: 10.7270/Q2FF3S51 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen activator inhibitor 1 (Homo sapiens (Human)) | BDBM50149275 (2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Michigan Medical School Curated by ChEMBL | Assay Description Inhibition of vitronectin binding to human PAI1 | J Biol Chem 282: 9288-96 (2007) Article DOI: 10.1074/jbc.M611642200 BindingDB Entry DOI: 10.7270/Q2FF3S51 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Plasminogen activator inhibitor 1 (Homo sapiens (Human)) | BDBM50149275 (2-(1-benzyl-5-(4-(trifluoromethoxy)phenyl)-1H-indo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a |
University of Michigan Medical School Curated by ChEMBL | Assay Description Binding affinity to human immobilized PAI1 by surface plasmon resonance | J Biol Chem 282: 9288-96 (2007) Article DOI: 10.1074/jbc.M611642200 BindingDB Entry DOI: 10.7270/Q2FF3S51 | |||||||||||
More data for this Ligand-Target Pair |