Affinity Data by PubMed id=17317569

PubMed code 17317569

Found 7 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM68271 (M-31850) Show SMILES CCCNCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM68272 (LU79953) Show SMILES CCCNCCCNCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM68270 (5141402) Show SMILES OCCCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM50106194 (1,3-dioxo-1H-benz[de]isoquinoline \| 1,8-Naphthalim...) Show SMILES O=C1NC(=O)c2cccc3cccc1c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM68269 (M-31867) Show SMILES CC(O)CCN1C(=O)c2cccc3cccc(C1=O)c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM68268 (M-31862) Show SMILES O=C1N(CCCc2ccccn2)C(=O)c2cccc3cccc1c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.08E+5	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair
Beta-hexosaminidase subunit alpha (Homo sapiens (Human))	BDBM68267 (M-31860) Show SMILES O=C1N(CC2CCCO2)C(=O)c2cccc3cccc1c23 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.38E+5	n/a	n/a	n/a	n/a	n/a	25
Research Institute, Hospital for Sick Children					Assay Description Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.				Chem Biol 14: 153-64 (2007) Article DOI: 10.1016/j.chembiol.2006.12.006 BindingDB Entry DOI: 10.7270/Q25B00W8
Research Institute, Hospital for Sick Children					More data for this Ligand-Target Pair

* indicates data uncertainty>20%