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PubMed code 1732537

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50008224
PNG
((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...)
Show SMILES CC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:22|
Show InChI InChI=1S/C20H25N3O/c1-4-12(2)22-20(24)14-8-16-15-6-5-7-17-19(15)13(10-21-17)9-18(16)23(3)11-14/h5-8,10,12,14,18,21H,4,9,11H2,1-3H3,(H,22,24)/t12-,14-,18-/m1/s1
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 2n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Affinity of the compound in displacing [3H]-8-OH-DPAT from rat hippocampal 5-HT1A receptor.

J Med Chem 35: 203-11 (1992)


BindingDB Entry DOI: 10.7270/Q2571B03
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM50008225
PNG
(7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quin...)
Show SMILES CC[C@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:22|
Show InChI InChI=1S/C20H25N3O/c1-4-12(2)22-20(24)14-8-16-15-6-5-7-17-19(15)13(10-21-17)9-18(16)23(3)11-14/h5-8,10,12,14,18,21H,4,9,11H2,1-3H3,(H,22,24)/t12-,14+,18+/m0/s1
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 4.60n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Affinity of the compound in displacing [3H]-8-OH-DPAT from rat hippocampal 5-hydroxytryptamine 1A receptor.

J Med Chem 35: 203-11 (1992)


BindingDB Entry DOI: 10.7270/Q2571B03
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 1A


(Rattus norvegicus (rat))		BDBM21342
PNG
((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...)
Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12|
Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1
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PubMed
 5.10n/an/an/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Affinity of the compound in displacing [3H]-8-OH-DPAT from rat hippocampal 5-HT1A receptor.

J Med Chem 35: 203-11 (1992)


BindingDB Entry DOI: 10.7270/Q2571B03
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%