BindingDB logo
myBDB logout

PubMed code 17329254

Compile data set for download or QSAR
Found 33 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173799
PNG
((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)
Show SMILES OP(O)(=O)C(Nc1cccc(Br)c1)P(O)(O)=O
Show InChI InChI=1S/C7H10BrNO6P2/c8-5-2-1-3-6(4-5)9-7(16(10,11)12)17(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 400n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2 by competitive inhibition assay

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50180152
PNG
((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)
Show SMILES CCn1c2ccccc2c2cc(NC(P(O)(O)=O)P(O)(O)=O)ccc12
Show InChI InChI=1S/C15H18N2O6P2/c1-2-17-13-6-4-3-5-11(13)12-9-10(7-8-14(12)17)16-15(24(18,19)20)25(21,22)23/h3-9,15-16H,2H2,1H3,(H2,18,19,20)(H2,21,22,23)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 500n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2 by competitive inhibition assay

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173799
PNG
((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)
Show SMILES OP(O)(=O)C(Nc1cccc(Br)c1)P(O)(O)=O
Show InChI InChI=1S/C7H10BrNO6P2/c8-5-2-1-3-6(4-5)9-7(16(10,11)12)17(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 600n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2 by competitive inhibition assay

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50180152
PNG
((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)
Show SMILES CCn1c2ccccc2c2cc(NC(P(O)(O)=O)P(O)(O)=O)ccc12
Show InChI InChI=1S/C15H18N2O6P2/c1-2-17-13-6-4-3-5-11(13)12-9-10(7-8-14(12)17)16-15(24(18,19)20)25(21,22)23/h3-9,15-16H,2H2,1H3,(H2,18,19,20)(H2,21,22,23)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 1.20E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2 by competitive inhibition assay

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173799
PNG
((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)
Show SMILES OP(O)(=O)C(Nc1cccc(Br)c1)P(O)(O)=O
Show InChI InChI=1S/C7H10BrNO6P2/c8-5-2-1-3-6(4-5)9-7(16(10,11)12)17(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 1.20E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50180152
PNG
((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)
Show SMILES CCn1c2ccccc2c2cc(NC(P(O)(O)=O)P(O)(O)=O)ccc12
Show InChI InChI=1S/C15H18N2O6P2/c1-2-17-13-6-4-3-5-11(13)12-9-10(7-8-14(12)17)16-15(24(18,19)20)25(21,22)23/h3-9,15-16H,2H2,1H3,(H2,18,19,20)(H2,21,22,23)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 1.70E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2 by competitive inhibition assay

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50180152
PNG
((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)
Show SMILES CCn1c2ccccc2c2cc(NC(P(O)(O)=O)P(O)(O)=O)ccc12
Show InChI InChI=1S/C15H18N2O6P2/c1-2-17-13-6-4-3-5-11(13)12-9-10(7-8-14(12)17)16-15(24(18,19)20)25(21,22)23/h3-9,15-16H,2H2,1H3,(H2,18,19,20)(H2,21,22,23)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 1.70E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50180152
PNG
((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)
Show SMILES CCn1c2ccccc2c2cc(NC(P(O)(O)=O)P(O)(O)=O)ccc12
Show InChI InChI=1S/C15H18N2O6P2/c1-2-17-13-6-4-3-5-11(13)12-9-10(7-8-14(12)17)16-15(24(18,19)20)25(21,22)23/h3-9,15-16H,2H2,1H3,(H2,18,19,20)(H2,21,22,23)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 2.40E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2 by competitive inhibition assay

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173799
PNG
((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)
Show SMILES OP(O)(=O)C(Nc1cccc(Br)c1)P(O)(O)=O
Show InChI InChI=1S/C7H10BrNO6P2/c8-5-2-1-3-6(4-5)9-7(16(10,11)12)17(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 2.60E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2 by competitive inhibition assay

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50180152
PNG
((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)
Show SMILES CCn1c2ccccc2c2cc(NC(P(O)(O)=O)P(O)(O)=O)ccc12
Show InChI InChI=1S/C15H18N2O6P2/c1-2-17-13-6-4-3-5-11(13)12-9-10(7-8-14(12)17)16-15(24(18,19)20)25(21,22)23/h3-9,15-16H,2H2,1H3,(H2,18,19,20)(H2,21,22,23)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 2.80E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50098386
PNG
((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)
Show SMILES OC(Cc1ccncc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)5-6-1-3-8-4-2-6/h1-4,9H,5H2,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 2.80E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2 by competitive inhibition assay

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173799
PNG
((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)
Show SMILES OP(O)(=O)C(Nc1cccc(Br)c1)P(O)(O)=O
Show InChI InChI=1S/C7H10BrNO6P2/c8-5-2-1-3-6(4-5)9-7(16(10,11)12)17(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 2.90E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2 by competitive inhibition assay

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50098386
PNG
((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)
Show SMILES OC(Cc1ccncc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)5-6-1-3-8-4-2-6/h1-4,9H,5H2,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 3.30E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2 by competitive inhibition assay

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50098386
PNG
((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)
Show SMILES OC(Cc1ccncc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)5-6-1-3-8-4-2-6/h1-4,9H,5H2,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 3.40E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2 by competitive inhibition assay

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50098386
PNG
((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)
Show SMILES OC(Cc1ccncc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)5-6-1-3-8-4-2-6/h1-4,9H,5H2,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 4.30E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50180152
PNG
((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)
Show SMILES CCn1c2ccccc2c2cc(NC(P(O)(O)=O)P(O)(O)=O)ccc12
Show InChI InChI=1S/C15H18N2O6P2/c1-2-17-13-6-4-3-5-11(13)12-9-10(7-8-14(12)17)16-15(24(18,19)20)25(21,22)23/h3-9,15-16H,2H2,1H3,(H2,18,19,20)(H2,21,22,23)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 4.30E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50098386
PNG
((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)
Show SMILES OC(Cc1ccncc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)5-6-1-3-8-4-2-6/h1-4,9H,5H2,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 6.00E+3n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50098386
PNG
((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)
Show SMILES OC(Cc1ccncc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)5-6-1-3-8-4-2-6/h1-4,9H,5H2,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 1.05E+4n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173799
PNG
((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)
Show SMILES OP(O)(=O)C(Nc1cccc(Br)c1)P(O)(O)=O
Show InChI InChI=1S/C7H10BrNO6P2/c8-5-2-1-3-6(4-5)9-7(16(10,11)12)17(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 1.06E+4n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50098386
PNG
((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)
Show SMILES OC(Cc1ccncc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)5-6-1-3-8-4-2-6/h1-4,9H,5H2,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 1.14E+4n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of ATP, 2 mM D-glucose and 3 mM MgCl2 by competitive inhibition assay

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50098386
PNG
((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)
Show SMILES OC(Cc1ccncc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)5-6-1-3-8-4-2-6/h1-4,9H,5H2,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
 4.39E+4n/an/an/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of glycosomal Trypanosoma cruzi hexokinase in presence of D-glucose, 1 mM ATP and 3 mM MgCl2

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173796
PNG
(CHEMBL450938 | [(3-nitro-phenylamino)-phosphono-me...)
Show SMILES OP(O)(=O)C(Nc1cccc(c1)[N+]([O-])=O)P(O)(O)=O
Show InChI InChI=1S/C7H10N2O8P2/c10-9(11)6-3-1-2-5(4-6)8-7(18(12,13)14)19(15,16)17/h1-4,7-8H,(H2,12,13,14)(H2,15,16,17)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 810n/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173790
PNG
(2-(biphenyl-3-ylamino)ethane-1,1-diyldiphosphonic ...)
Show SMILES OP(O)(=O)C(CNc1cccc(c1)-c1ccccc1)P(O)(O)=O
Show InChI InChI=1S/C14H17NO6P2/c16-22(17,18)14(23(19,20)21)10-15-13-8-4-7-12(9-13)11-5-2-1-3-6-11/h1-9,14-15H,10H2,(H2,16,17,18)(H2,19,20,21)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 810n/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173787
PNG
((3-(hydroxymethyl)phenylamino)methylenediphosphoni...)
Show SMILES OCc1cccc(NC(P(O)(O)=O)P(O)(O)=O)c1
Show InChI InChI=1S/C8H13NO7P2/c10-5-6-2-1-3-7(4-6)9-8(17(11,12)13)18(14,15)16/h1-4,8-10H,5H2,(H2,11,12,13)(H2,14,15,16)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 810n/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173752
PNG
((3-(methoxymethyl)phenylamino)methylenediphosphoni...)
Show SMILES COCc1cccc(NC(P(O)(O)=O)P(O)(O)=O)c1
Show InChI InChI=1S/C9H15NO7P2/c1-17-6-7-3-2-4-8(5-7)10-9(18(11,12)13)19(14,15)16/h2-5,9-10H,6H2,1H3,(H2,11,12,13)(H2,14,15,16)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 810n/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM25269
PNG
((1-hydroxy-1-phosphonodecyl)phosphonic acid | CHEM...)
Show SMILES CCCCCCCCCC(O)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C10H24O7P2/c1-2-3-4-5-6-7-8-9-10(11,18(12,13)14)19(15,16)17/h11H,2-9H2,1H3,(H2,12,13,14)(H2,15,16,17)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 810n/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173794
PNG
((3',4'-difluorobiphenyl-3-ylamino)methylenediphosp...)
Show SMILES OP(O)(=O)C(Nc1cccc(c1)-c1ccc(F)c(F)c1)P(O)(O)=O
Show InChI InChI=1S/C13H13F2NO6P2/c14-11-5-4-9(7-12(11)15)8-2-1-3-10(6-8)16-13(23(17,18)19)24(20,21)22/h1-7,13,16H,(H2,17,18,19)(H2,20,21,22)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 810n/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173768
PNG
((biphenyl-3-yl-hydroxy-phosphono-methyl)-phosphoni...)
Show SMILES OC(c1cccc(c1)-c1ccccc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C13H14O7P2/c14-13(21(15,16)17,22(18,19)20)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9,14H,(H2,15,16,17)(H2,18,19,20)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 810n/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50138049
PNG
((4-heptylphenylamino)methylenediphosphonic acid | ...)
Show SMILES CCCCCCCc1ccc(NC(P(O)(O)=O)P(O)(O)=O)cc1
Show InChI InChI=1S/C14H25NO6P2/c1-2-3-4-5-6-7-12-8-10-13(11-9-12)15-14(22(16,17)18)23(19,20)21/h8-11,14-15H,2-7H2,1H3,(H2,16,17,18)(H2,19,20,21)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 810n/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50138040
PNG
((biphenyl-3-ylamino)methylenediphosphonic acid | B...)
Show SMILES OP(O)(=O)C(Nc1cccc(c1)-c1ccccc1)P(O)(O)=O
Show InChI InChI=1S/C13H15NO6P2/c15-21(16,17)13(22(18,19)20)14-12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9,13-14H,(H2,15,16,17)(H2,18,19,20)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 810n/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50180152
PNG
((9-ethyl-9H-3-carbazolyl)-aminomethylene-1,1-bisph...)
Show SMILES CCn1c2ccccc2c2cc(NC(P(O)(O)=O)P(O)(O)=O)ccc12
Show InChI InChI=1S/C15H18N2O6P2/c1-2-17-13-6-4-3-5-11(13)12-9-10(7-8-14(12)17)16-15(24(18,19)20)25(21,22)23/h3-9,15-16H,2H2,1H3,(H2,18,19,20)(H2,21,22,23)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 810n/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50173799
PNG
((3-bromo-phenyl)-aminomethylene-1,1-bisphosphonate...)
Show SMILES OP(O)(=O)C(Nc1cccc(Br)c1)P(O)(O)=O
Show InChI InChI=1S/C7H10BrNO6P2/c8-5-2-1-3-6(4-5)9-7(16(10,11)12)17(13,14)15/h1-4,7,9H,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 950n/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
Phosphotransferase


(Trypanosoma cruzi)		BDBM50098386
PNG
((1-hydroxy-1-phosphono-2-pyridin-4-yl-ethyl)-phosp...)
Show SMILES OC(Cc1ccncc1)(P(O)(O)=O)P(O)(O)=O
Show InChI InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)5-6-1-3-8-4-2-6/h1-4,9H,5H2,(H2,10,11,12)(H2,13,14,15)
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 1.27E+4n/an/an/an/an/an/a



Instituto Venezolano de Investigaciones Cient£ficas

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi hexokinase

J Biol Chem 282: 12377-87 (2007)


Article DOI: 10.1074/jbc.M607286200
BindingDB Entry DOI: 10.7270/Q2FT8MXH
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%