Affinity Data by PubMed id=17346959

PubMed code 17346959

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50015149 (CHEMBL156887 \| N-Hydroxy-4-naphthalen-1-yl-benzami...) Show SMILES ONC(=O)c1ccc(cc1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC8 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50207560 (CHEMBL245548 \| N-hydroxy-3-(naphthalen-1-yl)acryla...) Show SMILES ONC(=O)\C=C\c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC8 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50207559 (CHEMBL245741 \| N-hydroxy-3-phenoxybenzamide) Show SMILES ONC(=O)c1cccc(Oc2ccccc2)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	6.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC8 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50015152 (CHEMBL115468 \| N-hydroxy-1-naphthamide \| Naphthale...) Show SMILES ONC(=O)c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC8 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50015109 (CHEMBL154517 \| biphenyl-3-carboxylic acid hydroxya...) Show SMILES ONC(=O)c1cccc(c1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC8 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50015149 (CHEMBL156887 \| N-Hydroxy-4-naphthalen-1-yl-benzami...) Show SMILES ONC(=O)c1ccc(cc1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC6 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50207561 (CHEMBL396097 \| Class IIa HDAC inhibitor, Compound ...) Show SMILES ONC(=O)C(c1ccccc1)c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC8 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50207560 (CHEMBL245548 \| N-hydroxy-3-(naphthalen-1-yl)acryla...) Show SMILES ONC(=O)\C=C\c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC6 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50015152 (CHEMBL115468 \| N-hydroxy-1-naphthamide \| Naphthale...) Show SMILES ONC(=O)c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC6 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50015149 (CHEMBL156887 \| N-Hydroxy-4-naphthalen-1-yl-benzami...) Show SMILES ONC(=O)c1ccc(cc1)-c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC1 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50015109 (CHEMBL154517 \| biphenyl-3-carboxylic acid hydroxya...) Show SMILES ONC(=O)c1cccc(c1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC1 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50015152 (CHEMBL115468 \| N-hydroxy-1-naphthamide \| Naphthale...) Show SMILES ONC(=O)c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC1 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50015109 (CHEMBL154517 \| biphenyl-3-carboxylic acid hydroxya...) Show SMILES ONC(=O)c1cccc(c1)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC6 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50207560 (CHEMBL245548 \| N-hydroxy-3-(naphthalen-1-yl)acryla...) Show SMILES ONC(=O)\C=C\c1cccc2ccccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Ithaca College Curated by ChEMBL					Assay Description Inhibition of human HDAC1 by [3H]acetyl histone peptide assay				Bioorg Med Chem Lett 17: 2874-8 (2007) Article DOI: 10.1016/j.bmcl.2007.02.064 BindingDB Entry DOI: 10.7270/Q2513XWG
Ithaca College Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%