Affinity Data by PubMed id=17374486

PubMed code 17374486

Found 6 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Suisan Kaisha, Ltd Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake				Bioorg Med Chem 15: 3445-9 (2007) Article DOI: 10.1016/j.bmc.2007.03.011 BindingDB Entry DOI: 10.7270/Q25X28N2
Nippon Suisan Kaisha, Ltd Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Suisan Kaisha, Ltd Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake				Bioorg Med Chem 15: 3445-9 (2007) Article DOI: 10.1016/j.bmc.2007.03.011 BindingDB Entry DOI: 10.7270/Q25X28N2
Nippon Suisan Kaisha, Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50208612 ((-)-kurarinone \| (2S)-2-(2,4-dihydroxyphenyl)-7-hy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Suisan Kaisha, Ltd Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake				Bioorg Med Chem 15: 3445-9 (2007) Article DOI: 10.1016/j.bmc.2007.03.011 BindingDB Entry DOI: 10.7270/Q25X28N2
Nippon Suisan Kaisha, Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50208611 ((2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Suisan Kaisha, Ltd Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake				Bioorg Med Chem 15: 3445-9 (2007) Article DOI: 10.1016/j.bmc.2007.03.011 BindingDB Entry DOI: 10.7270/Q25X28N2
Nippon Suisan Kaisha, Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50208612 ((-)-kurarinone \| (2S)-2-(2,4-dihydroxyphenyl)-7-hy...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Suisan Kaisha, Ltd Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake				Bioorg Med Chem 15: 3445-9 (2007) Article DOI: 10.1016/j.bmc.2007.03.011 BindingDB Entry DOI: 10.7270/Q25X28N2
Nippon Suisan Kaisha, Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (Homo sapiens (Human))	BDBM50208611 ((2S)-2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-8-[(2R)...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
Nippon Suisan Kaisha, Ltd Curated by ChEMBL					Assay Description Inhibition of human SGLT1 expressed in COS1 cells assessed as [14C]methyl-alpha-D-glucopyranoside uptake				Bioorg Med Chem 15: 3445-9 (2007) Article DOI: 10.1016/j.bmc.2007.03.011 BindingDB Entry DOI: 10.7270/Q25X28N2
Nippon Suisan Kaisha, Ltd Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%