Found 99 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM11162
((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Similars
| DrugBank
PDB
Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM15561
((3R)-3-amino-4-(5-chloro-2-fluorophenyl)-1-[3-(tri...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(Cl)ccc1F |r| Show InChI InChI=1S/C16H16ClF4N5O/c17-10-1-2-12(18)9(5-10)6-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,5,11H,3-4,6-8,22H2/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210657
((R)-3-amino-4-(2,4-dichlorophenyl)-1-(3-(trifluoro...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(Cl)cc1Cl Show InChI InChI=1S/C16H16Cl2F3N5O/c17-10-2-1-9(12(18)6-10)5-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,6,11H,3-5,7-8,22H2/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM11160
((3R)-3-amino-4-(2,5-difluorophenyl)-1-[3-(trifluor...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C16H16F5N5O/c17-10-1-2-12(18)9(5-10)6-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,5,11H,3-4,6-8,22H2/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210649
((R)-3-amino-1-(3-(difluoromethyl)-5,6-dihydro-[1,2...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)F)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C16H16F5N5O/c17-10-6-12(19)11(18)4-8(10)3-9(22)5-14(27)25-1-2-26-13(7-25)23-24-16(26)15(20)21/h4,6,9,15H,1-3,5,7,22H2/t9-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210668
((3R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(2,4-difl...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccc(F)cc1F)Cc1cc(F)ccc1F Show InChI InChI=1S/C21H19F4N5O/c22-13-2-4-17(24)12(7-13)8-15(26)10-20(31)29-5-6-30-19(11-29)27-28-21(30)16-3-1-14(23)9-18(16)25/h1-4,7,9,15H,5-6,8,10-11,26H2/t15-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210647
((R)-3-amino-1-(3-cyclopropyl-5,6-dihydro-[1,2,4]tr...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C1CC1)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C18H20F3N5O/c19-13-8-15(21)14(20)6-11(13)5-12(22)7-17(27)25-3-4-26-16(9-25)23-24-18(26)10-1-2-10/h6,8,10,12H,1-5,7,9,22H2/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210652
((R)-3-amino-1-(3-ethyl-5,6-dihydro-[1,2,4]triazolo...)Show SMILES CCc1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C17H20F3N5O/c1-2-15-22-23-16-9-24(3-4-25(15)16)17(26)7-11(21)5-10-6-13(19)14(20)8-12(10)18/h6,8,11H,2-5,7,9,21H2,1H3/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210650
((R)-3-amino-4-(3-chlorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cccc(Cl)c1 Show InChI InChI=1S/C16H17ClF3N5O/c17-11-3-1-2-10(6-11)7-12(21)8-14(26)24-4-5-25-13(9-24)22-23-15(25)16(18,19)20/h1-3,6,12H,4-5,7-9,21H2/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210672
((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(4-fluorop...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccc(F)cc1)Cc1cc(F)ccc1F Show InChI InChI=1S/C21H20F3N5O/c22-15-3-1-13(2-4-15)21-27-26-19-12-28(7-8-29(19)21)20(30)11-17(25)10-14-9-16(23)5-6-18(14)24/h1-6,9,17H,7-8,10-12,25H2/t17-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210648
((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(pyridin-4...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccncc1)Cc1cc(F)ccc1F Show InChI InChI=1S/C20H20F2N6O/c21-15-1-2-17(22)14(9-15)10-16(23)11-19(29)27-7-8-28-18(12-27)25-26-20(28)13-3-5-24-6-4-13/h1-6,9,16H,7-8,10-12,23H2/t16-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210670
((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(hydroxyme...)Show SMILES N[C@@H](CC(=O)N1CCn2c(CO)nnc2C1)Cc1cc(F)ccc1F Show InChI InChI=1S/C16H19F2N5O2/c17-11-1-2-13(18)10(5-11)6-12(19)7-16(25)22-3-4-23-14(8-22)20-21-15(23)9-24/h1-2,5,12,24H,3-4,6-9,19H2/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210669
((R)-3-amino-4-(4-chloro-2,5-difluorophenyl)-1-(3-(...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(Cl)cc1F Show InChI InChI=1S/C16H15ClF5N5O/c17-10-6-11(18)8(4-12(10)19)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210665
((R)-3-amino-4-(2,4-difluorophenyl)-1-(3-(trifluoro...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(F)cc1F Show InChI InChI=1S/C16H16F5N5O/c17-10-2-1-9(12(18)6-10)5-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,6,11H,3-5,7-8,22H2/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210643
((R)-3-amino-4-(2-chloro-4,5-difluorophenyl)-1-(3-(...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1Cl Show InChI InChI=1S/C16H15ClF5N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 84 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210658
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1c(F)cc(F)cc1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-8-3-11(18)10(12(19)4-8)5-9(23)6-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h3-4,9H,1-2,5-7,23H2/t9-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210663
((R)-3-amino-4-(2-fluorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1F |r| Show InChI InChI=1S/C16H17F4N5O/c17-12-4-2-1-3-10(12)7-11(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,11H,5-9,21H2/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 98 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM11159
((1R)-1-(3,4-difluorobenzyl)-3-oxo-3-[3-(trifluorom...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(F)c(F)c1 |r| Show InChI InChI=1S/C16H16F5N5O/c17-11-2-1-9(6-12(11)18)5-10(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,6,10H,3-5,7-8,22H2/t10-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210662
((R)-3-amino-4-(3-fluorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cccc(F)c1 Show InChI InChI=1S/C16H17F4N5O/c17-11-3-1-2-10(6-11)7-12(21)8-14(26)24-4-5-25-13(9-24)22-23-15(25)16(18,19)20/h1-3,6,12H,4-5,7-9,21H2/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 135 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210661
((R)-3-amino-4-(2-chlorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1Cl Show InChI InChI=1S/C16H17ClF3N5O/c17-12-4-2-1-3-10(12)7-11(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,11H,5-9,21H2/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 145 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210653
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1c(F)ccc(F)c1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-10-1-2-11(18)14(19)9(10)5-8(23)6-13(28)26-3-4-27-12(7-26)24-25-15(27)16(20,21)22/h1-2,8H,3-7,23H2/t8-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 151 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210664
((R)-3-amino-4-(2,5-dichlorophenyl)-1-(3-(trifluoro...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(Cl)ccc1Cl Show InChI InChI=1S/C16H16Cl2F3N5O/c17-10-1-2-12(18)9(5-10)6-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,5,11H,3-4,6-8,22H2/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210651
((R)-ethyl 7-(3-amino-4-(2,5-difluorophenyl)butanoy...)Show SMILES CCOC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)ccc1F Show InChI InChI=1S/C18H21F2N5O3/c1-2-28-18(27)17-23-22-15-10-24(5-6-25(15)17)16(26)9-13(21)8-11-7-12(19)3-4-14(11)20/h3-4,7,13H,2,5-6,8-10,21H2,1H3/t13-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210666
((R)-ethyl 7-(3-amino-4-(2,4,5-trifluorophenyl)buta...)Show SMILES CCOC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C18H20F3N5O3/c1-2-29-18(28)17-24-23-15-9-25(3-4-26(15)17)16(27)7-11(22)5-10-6-13(20)14(21)8-12(10)19/h6,8,11H,2-5,7,9,22H2,1H3/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 219 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210671
((R)-7-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-...)Show SMILES CC(C)(C)NC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C20H25F3N6O2/c1-20(2,3)25-19(31)18-27-26-16-10-28(4-5-29(16)18)17(30)8-12(24)6-11-7-14(22)15(23)9-13(11)21/h7,9,12H,4-6,8,10,24H2,1-3H3,(H,25,31)/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 234 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210660
((R)-3-amino-4-(4-chlorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C16H17ClF3N5O/c17-11-3-1-10(2-4-11)7-12(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,12H,5-9,21H2/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 264 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210645
((R)-3-amino-4-(4-fluorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(F)cc1 Show InChI InChI=1S/C16H17F4N5O/c17-11-3-1-10(2-4-11)7-12(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,12H,5-9,21H2/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 272 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210659
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C17H17F6N5O/c18-16(19,20)11-3-1-2-10(6-11)7-12(24)8-14(29)27-4-5-28-13(9-27)25-26-15(28)17(21,22)23/h1-3,6,12H,4-5,7-9,24H2/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 366 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210644
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1C(F)(F)F Show InChI InChI=1S/C17H17F6N5O/c18-16(19,20)12-4-2-1-3-10(12)7-11(24)8-14(29)27-5-6-28-13(9-27)25-26-15(28)17(21,22)23/h1-4,11H,5-9,24H2/t11-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 486 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210667
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F6N5O/c18-16(19,20)11-3-1-10(2-4-11)7-12(24)8-14(29)27-5-6-28-13(9-27)25-26-15(28)17(21,22)23/h1-4,12H,5-9,24H2/t12-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 511 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210655
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)cc(F)c1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-9-3-8(14(19)11(18)5-9)4-10(23)6-13(28)26-1-2-27-12(7-26)24-25-15(27)16(20,21)22/h3,5,10H,1-2,4,6-7,23H2/t10-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 805 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210672
((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(4-fluorop...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccc(F)cc1)Cc1cc(F)ccc1F Show InChI InChI=1S/C21H20F3N5O/c22-15-3-1-13(2-4-15)21-27-26-19-12-28(7-8-29(19)21)20(30)11-17(25)10-14-9-16(23)5-6-18(14)24/h1-6,9,17H,7-8,10-12,25H2/t17-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 979 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210668
((3R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(2,4-difl...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccc(F)cc1F)Cc1cc(F)ccc1F Show InChI InChI=1S/C21H19F4N5O/c22-13-2-4-17(24)12(7-13)8-15(26)10-20(31)29-5-6-30-19(11-29)27-28-21(30)16-3-1-14(23)9-18(16)25/h1-4,7,9,15H,5-6,8,10-11,26H2/t15-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210654
((R)-3-amino-4-(perfluorophenyl)-1-(3-(trifluoromet...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1c(F)c(F)c(F)c(F)c1F Show InChI InChI=1S/C16H13F8N5O/c17-10-7(11(18)13(20)14(21)12(10)19)3-6(25)4-9(30)28-1-2-29-8(5-28)26-27-15(29)16(22,23)24/h6H,1-5,25H2/t6-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50210656
((R)-3-amino-4-(3,4-dichlorophenyl)-1-(3-(trifluoro...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H16Cl2F3N5O/c17-11-2-1-9(6-12(11)18)5-10(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,6,10H,3-5,7-8,22H2/t10-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP4 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210648
((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(pyridin-4...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccncc1)Cc1cc(F)ccc1F Show InChI InChI=1S/C20H20F2N6O/c21-15-1-2-17(22)14(9-15)10-16(23)11-19(29)27-7-8-28-18(12-27)25-26-20(28)13-3-5-24-6-4-13/h1-6,9,16H,7-8,10-12,23H2/t16-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210653
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1c(F)ccc(F)c1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-10-1-2-11(18)14(19)9(10)5-8(23)6-13(28)26-3-4-27-12(7-26)24-25-15(27)16(20,21)22/h1-2,8H,3-7,23H2/t8-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210658
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1c(F)cc(F)cc1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-8-3-11(18)10(12(19)4-8)5-9(23)6-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h3-4,9H,1-2,5-7,23H2/t9-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210655
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)cc(F)c1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-9-3-8(14(19)11(18)5-9)4-10(23)6-13(28)26-1-2-27-12(7-26)24-25-15(27)16(20,21)22/h3,5,10H,1-2,4,6-7,23H2/t10-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210666
((R)-ethyl 7-(3-amino-4-(2,4,5-trifluorophenyl)buta...)Show SMILES CCOC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C18H20F3N5O3/c1-2-29-18(28)17-24-23-15-9-25(3-4-26(15)17)16(27)7-11(22)5-10-6-13(20)14(21)8-12(10)19/h6,8,11H,2-5,7,9,22H2,1H3/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210660
((R)-3-amino-4-(4-chlorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C16H17ClF3N5O/c17-11-3-1-10(2-4-11)7-12(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,12H,5-9,21H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210657
((R)-3-amino-4-(2,4-dichlorophenyl)-1-(3-(trifluoro...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(Cl)cc1Cl Show InChI InChI=1S/C16H16Cl2F3N5O/c17-10-2-1-9(12(18)6-10)5-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,6,11H,3-5,7-8,22H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210651
((R)-ethyl 7-(3-amino-4-(2,5-difluorophenyl)butanoy...)Show SMILES CCOC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)ccc1F Show InChI InChI=1S/C18H21F2N5O3/c1-2-28-18(27)17-23-22-15-10-24(5-6-25(15)17)16(26)9-13(21)8-11-7-12(19)3-4-14(11)20/h3-4,7,13H,2,5-6,8-10,21H2,1H3/t13-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210652
((R)-3-amino-1-(3-ethyl-5,6-dihydro-[1,2,4]triazolo...)Show SMILES CCc1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C17H20F3N5O/c1-2-15-22-23-16-9-24(3-4-25(15)16)17(26)7-11(21)5-10-6-13(19)14(20)8-12(10)18/h6,8,11H,2-5,7,9,21H2,1H3/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM11159
((1R)-1-(3,4-difluorobenzyl)-3-oxo-3-[3-(trifluorom...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(F)c(F)c1 |r| Show InChI InChI=1S/C16H16F5N5O/c17-11-2-1-9(6-12(11)18)5-10(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,6,10H,3-5,7-8,22H2/t10-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM11162
((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210669
((R)-3-amino-4-(4-chloro-2,5-difluorophenyl)-1-(3-(...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(Cl)cc1F Show InChI InChI=1S/C16H15ClF5N5O/c17-10-6-11(18)8(4-12(10)19)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210657
((R)-3-amino-4-(2,4-dichlorophenyl)-1-(3-(trifluoro...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(Cl)cc1Cl Show InChI InChI=1S/C16H16Cl2F3N5O/c17-10-2-1-9(12(18)6-10)5-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,6,11H,3-5,7-8,22H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210647
((R)-3-amino-1-(3-cyclopropyl-5,6-dihydro-[1,2,4]tr...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C1CC1)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C18H20F3N5O/c19-13-8-15(21)14(20)6-11(13)5-12(22)7-17(27)25-3-4-26-16(9-25)23-24-18(26)10-1-2-10/h6,8,10,12H,1-5,7,9,22H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210668
((3R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(2,4-difl...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccc(F)cc1F)Cc1cc(F)ccc1F Show InChI InChI=1S/C21H19F4N5O/c22-13-2-4-17(24)12(7-13)8-15(26)10-20(31)29-5-6-30-19(11-29)27-28-21(30)16-3-1-14(23)9-18(16)25/h1-4,7,9,15H,5-6,8,10-11,26H2/t15-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210671
((R)-7-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-...)Show SMILES CC(C)(C)NC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C20H25F3N6O2/c1-20(2,3)25-19(31)18-27-26-16-10-28(4-5-29(16)18)17(30)8-12(24)6-11-7-14(22)15(23)9-13(11)21/h7,9,12H,4-6,8,10,24H2,1-3H3,(H,25,31)/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210645
((R)-3-amino-4-(4-fluorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(F)cc1 Show InChI InChI=1S/C16H17F4N5O/c17-11-3-1-10(2-4-11)7-12(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,12H,5-9,21H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM11160
((3R)-3-amino-4-(2,5-difluorophenyl)-1-[3-(trifluor...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C16H16F5N5O/c17-10-1-2-12(18)9(5-10)6-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,5,11H,3-4,6-8,22H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210660
((R)-3-amino-4-(4-chlorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(Cl)cc1 Show InChI InChI=1S/C16H17ClF3N5O/c17-11-3-1-10(2-4-11)7-12(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,12H,5-9,21H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210663
((R)-3-amino-4-(2-fluorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1F |r| Show InChI InChI=1S/C16H17F4N5O/c17-12-4-2-1-3-10(12)7-11(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,11H,5-9,21H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210651
((R)-ethyl 7-(3-amino-4-(2,5-difluorophenyl)butanoy...)Show SMILES CCOC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)ccc1F Show InChI InChI=1S/C18H21F2N5O3/c1-2-28-18(27)17-23-22-15-10-24(5-6-25(15)17)16(26)9-13(21)8-11-7-12(19)3-4-14(11)20/h3-4,7,13H,2,5-6,8-10,21H2,1H3/t13-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >7.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210666
((R)-ethyl 7-(3-amino-4-(2,4,5-trifluorophenyl)buta...)Show SMILES CCOC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C18H20F3N5O3/c1-2-29-18(28)17-24-23-15-9-25(3-4-26(15)17)16(27)7-11(22)5-10-6-13(20)14(21)8-12(10)19/h6,8,11H,2-5,7,9,22H2,1H3/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210665
((R)-3-amino-4-(2,4-difluorophenyl)-1-(3-(trifluoro...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(F)cc1F Show InChI InChI=1S/C16H16F5N5O/c17-10-2-1-9(12(18)6-10)5-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,6,11H,3-5,7-8,22H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210649
((R)-3-amino-1-(3-(difluoromethyl)-5,6-dihydro-[1,2...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)F)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C16H16F5N5O/c17-10-6-12(19)11(18)4-8(10)3-9(22)5-14(27)25-1-2-26-13(7-25)23-24-16(26)15(20)21/h4,6,9,15H,1-3,5,7,22H2/t9-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM15561
((3R)-3-amino-4-(5-chloro-2-fluorophenyl)-1-[3-(tri...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(Cl)ccc1F |r| Show InChI InChI=1S/C16H16ClF4N5O/c17-10-1-2-12(18)9(5-10)6-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,5,11H,3-4,6-8,22H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 9.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210643
((R)-3-amino-4-(2-chloro-4,5-difluorophenyl)-1-(3-(...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1Cl Show InChI InChI=1S/C16H15ClF5N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210654
((R)-3-amino-4-(perfluorophenyl)-1-(3-(trifluoromet...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1c(F)c(F)c(F)c(F)c1F Show InChI InChI=1S/C16H13F8N5O/c17-10-7(11(18)13(20)14(21)12(10)19)3-6(25)4-9(30)28-1-2-29-8(5-28)26-27-15(29)16(22,23)24/h6H,1-5,25H2/t6-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210672
((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(4-fluorop...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccc(F)cc1)Cc1cc(F)ccc1F Show InChI InChI=1S/C21H20F3N5O/c22-15-3-1-13(2-4-15)21-27-26-19-12-28(7-8-29(19)21)20(30)11-17(25)10-14-9-16(23)5-6-18(14)24/h1-6,9,17H,7-8,10-12,25H2/t17-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210661
((R)-3-amino-4-(2-chlorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1Cl Show InChI InChI=1S/C16H17ClF3N5O/c17-12-4-2-1-3-10(12)7-11(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,11H,5-9,21H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210650
((R)-3-amino-4-(3-chlorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cccc(Cl)c1 Show InChI InChI=1S/C16H17ClF3N5O/c17-11-3-1-2-10(6-11)7-12(21)8-14(26)24-4-5-25-13(9-24)22-23-15(25)16(18,19)20/h1-3,6,12H,4-5,7-9,21H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210667
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F6N5O/c18-16(19,20)11-3-1-10(2-4-11)7-12(24)8-14(29)27-5-6-28-13(9-27)25-26-15(28)17(21,22)23/h1-4,12H,5-9,24H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210648
((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(pyridin-4...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2-c1ccncc1)Cc1cc(F)ccc1F Show InChI InChI=1S/C20H20F2N6O/c21-15-1-2-17(22)14(9-15)10-16(23)11-19(29)27-7-8-28-18(12-27)25-26-20(28)13-3-5-24-6-4-13/h1-6,9,16H,7-8,10-12,23H2/t16-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210669
((R)-3-amino-4-(4-chloro-2,5-difluorophenyl)-1-(3-(...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(Cl)cc1F Show InChI InChI=1S/C16H15ClF5N5O/c17-10-6-11(18)8(4-12(10)19)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210671
((R)-7-(3-amino-4-(2,4,5-trifluorophenyl)butanoyl)-...)Show SMILES CC(C)(C)NC(=O)c1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C20H25F3N6O2/c1-20(2,3)25-19(31)18-27-26-16-10-28(4-5-29(16)18)17(30)8-12(24)6-11-7-14(22)15(23)9-13(11)21/h7,9,12H,4-6,8,10,24H2,1-3H3,(H,25,31)/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210653
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1c(F)ccc(F)c1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-10-1-2-11(18)14(19)9(10)5-8(23)6-13(28)26-3-4-27-12(7-26)24-25-15(27)16(20,21)22/h1-2,8H,3-7,23H2/t8-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210665
((R)-3-amino-4-(2,4-difluorophenyl)-1-(3-(trifluoro...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(F)cc1F Show InChI InChI=1S/C16H16F5N5O/c17-10-2-1-9(12(18)6-10)5-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,6,11H,3-5,7-8,22H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210654
((R)-3-amino-4-(perfluorophenyl)-1-(3-(trifluoromet...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1c(F)c(F)c(F)c(F)c1F Show InChI InChI=1S/C16H13F8N5O/c17-10-7(11(18)13(20)14(21)12(10)19)3-6(25)4-9(30)28-1-2-29-8(5-28)26-27-15(29)16(22,23)24/h6H,1-5,25H2/t6-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210670
((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(hydroxyme...)Show SMILES N[C@@H](CC(=O)N1CCn2c(CO)nnc2C1)Cc1cc(F)ccc1F Show InChI InChI=1S/C16H19F2N5O2/c17-11-1-2-13(18)10(5-11)6-12(19)7-16(25)22-3-4-23-14(8-22)20-21-15(23)9-24/h1-2,5,12,24H,3-4,6-9,19H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210659
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C17H17F6N5O/c18-16(19,20)11-3-1-2-10(6-11)7-12(24)8-14(29)27-4-5-28-13(9-27)25-26-15(28)17(21,22)23/h1-3,6,12H,4-5,7-9,24H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210667
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C17H17F6N5O/c18-16(19,20)11-3-1-10(2-4-11)7-12(24)8-14(29)27-5-6-28-13(9-27)25-26-15(28)17(21,22)23/h1-4,12H,5-9,24H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210645
((R)-3-amino-4-(4-fluorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(F)cc1 Show InChI InChI=1S/C16H17F4N5O/c17-11-3-1-10(2-4-11)7-12(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,12H,5-9,21H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210652
((R)-3-amino-1-(3-ethyl-5,6-dihydro-[1,2,4]triazolo...)Show SMILES CCc1nnc2CN(CCn12)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C17H20F3N5O/c1-2-15-22-23-16-9-24(3-4-25(15)16)17(26)7-11(21)5-10-6-13(19)14(20)8-12(10)18/h6,8,11H,2-5,7,9,21H2,1H3/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210658
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1c(F)cc(F)cc1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-8-3-11(18)10(12(19)4-8)5-9(23)6-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h3-4,9H,1-2,5-7,23H2/t9-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210656
((R)-3-amino-4-(3,4-dichlorophenyl)-1-(3-(trifluoro...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H16Cl2F3N5O/c17-11-2-1-9(6-12(11)18)5-10(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,6,10H,3-5,7-8,22H2/t10-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM11159
((1R)-1-(3,4-difluorobenzyl)-3-oxo-3-[3-(trifluorom...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(F)c(F)c1 |r| Show InChI InChI=1S/C16H16F5N5O/c17-11-2-1-9(6-12(11)18)5-10(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,6,10H,3-5,7-8,22H2/t10-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210670
((R)-3-amino-4-(2,5-difluorophenyl)-1-(3-(hydroxyme...)Show SMILES N[C@@H](CC(=O)N1CCn2c(CO)nnc2C1)Cc1cc(F)ccc1F Show InChI InChI=1S/C16H19F2N5O2/c17-11-1-2-13(18)10(5-11)6-12(19)7-16(25)22-3-4-23-14(8-22)20-21-15(23)9-24/h1-2,5,12,24H,3-4,6-9,19H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210650
((R)-3-amino-4-(3-chlorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cccc(Cl)c1 Show InChI InChI=1S/C16H17ClF3N5O/c17-11-3-1-2-10(6-11)7-12(21)8-14(26)24-4-5-25-13(9-24)22-23-15(25)16(18,19)20/h1-3,6,12H,4-5,7-9,21H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210664
((R)-3-amino-4-(2,5-dichlorophenyl)-1-(3-(trifluoro...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(Cl)ccc1Cl Show InChI InChI=1S/C16H16Cl2F3N5O/c17-10-1-2-12(18)9(5-10)6-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,5,11H,3-4,6-8,22H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210643
((R)-3-amino-4-(2-chloro-4,5-difluorophenyl)-1-(3-(...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1Cl Show InChI InChI=1S/C16H15ClF5N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM11162
((1R)-3-oxo-3-[3-(trifluoroethyl)-5,6-dihydro[1,2,4...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)c(F)cc1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-10-6-12(19)11(18)4-8(10)3-9(23)5-14(28)26-1-2-27-13(7-26)24-25-15(27)16(20,21)22/h4,6,9H,1-3,5,7,23H2/t9-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
PDB
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210659
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C17H17F6N5O/c18-16(19,20)11-3-1-2-10(6-11)7-12(24)8-14(29)27-4-5-28-13(9-27)25-26-15(28)17(21,22)23/h1-3,6,12H,4-5,7-9,24H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210662
((R)-3-amino-4-(3-fluorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cccc(F)c1 Show InChI InChI=1S/C16H17F4N5O/c17-11-3-1-2-10(6-11)7-12(21)8-14(26)24-4-5-25-13(9-24)22-23-15(25)16(18,19)20/h1-3,6,12H,4-5,7-9,21H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210656
((R)-3-amino-4-(3,4-dichlorophenyl)-1-(3-(trifluoro...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H16Cl2F3N5O/c17-11-2-1-9(6-12(11)18)5-10(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,6,10H,3-5,7-8,22H2/t10-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210649
((R)-3-amino-1-(3-(difluoromethyl)-5,6-dihydro-[1,2...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)F)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C16H16F5N5O/c17-10-6-12(19)11(18)4-8(10)3-9(22)5-14(27)25-1-2-26-13(7-25)23-24-16(26)15(20)21/h4,6,9,15H,1-3,5,7,22H2/t9-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210644
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1C(F)(F)F Show InChI InChI=1S/C17H17F6N5O/c18-16(19,20)12-4-2-1-3-10(12)7-11(24)8-14(29)27-5-6-28-13(9-27)25-26-15(28)17(21,22)23/h1-4,11H,5-9,24H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210661
((R)-3-amino-4-(2-chlorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1Cl Show InChI InChI=1S/C16H17ClF3N5O/c17-12-4-2-1-3-10(12)7-11(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,11H,5-9,21H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210662
((R)-3-amino-4-(3-fluorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cccc(F)c1 Show InChI InChI=1S/C16H17F4N5O/c17-11-3-1-2-10(6-11)7-12(21)8-14(26)24-4-5-25-13(9-24)22-23-15(25)16(18,19)20/h1-3,6,12H,4-5,7-9,21H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210647
((R)-3-amino-1-(3-cyclopropyl-5,6-dihydro-[1,2,4]tr...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C1CC1)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C18H20F3N5O/c19-13-8-15(21)14(20)6-11(13)5-12(22)7-17(27)25-3-4-26-16(9-25)23-24-18(26)10-1-2-10/h6,8,10,12H,1-5,7,9,22H2/t12-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM11160
((3R)-3-amino-4-(2,5-difluorophenyl)-1-[3-(trifluor...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)ccc1F |r| Show InChI InChI=1S/C16H16F5N5O/c17-10-1-2-12(18)9(5-10)6-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,5,11H,3-4,6-8,22H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210664
((R)-3-amino-4-(2,5-dichlorophenyl)-1-(3-(trifluoro...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(Cl)ccc1Cl Show InChI InChI=1S/C16H16Cl2F3N5O/c17-10-1-2-12(18)9(5-10)6-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,5,11H,3-4,6-8,22H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM50210644
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1C(F)(F)F Show InChI InChI=1S/C17H17F6N5O/c18-16(19,20)12-4-2-1-3-10(12)7-11(24)8-14(29)27-5-6-28-13(9-27)25-26-15(28)17(21,22)23/h1-4,11H,5-9,24H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210655
((R)-3-amino-1-(3-(trifluoromethyl)-5,6-dihydro-[1,...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(F)cc(F)c1F |r| Show InChI InChI=1S/C16H15F6N5O/c17-9-3-8(14(19)11(18)5-9)4-10(23)6-13(28)26-1-2-27-12(7-26)24-25-15(27)16(20,21)22/h3,5,10H,1-2,4,6-7,23H2/t10-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 9
(Homo sapiens (Human)) | BDBM50210663
((R)-3-amino-4-(2-fluorophenyl)-1-(3-(trifluorometh...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1ccccc1F |r| Show InChI InChI=1S/C16H17F4N5O/c17-12-4-2-1-3-10(12)7-11(21)8-14(26)24-5-6-25-13(9-24)22-23-15(25)16(18,19)20/h1-4,11H,5-9,21H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP9 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Dipeptidyl peptidase 8
(Homo sapiens (Human)) | BDBM15561
((3R)-3-amino-4-(5-chloro-2-fluorophenyl)-1-[3-(tri...)Show SMILES N[C@@H](CC(=O)N1CCn2c(C1)nnc2C(F)(F)F)Cc1cc(Cl)ccc1F |r| Show InChI InChI=1S/C16H16ClF4N5O/c17-10-1-2-12(18)9(5-10)6-11(22)7-14(27)25-3-4-26-13(8-25)23-24-15(26)16(19,20)21/h1-2,5,11H,3-4,6-8,22H2/t11-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of DPP8 activity |
Bioorg Med Chem Lett 17: 3373-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.03.098
BindingDB Entry DOI: 10.7270/Q2W37W04 |
More data for this
Ligand-Target Pair | |
Search and Browse
