Found 146 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211992
(CHEMBL236419 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES FC(F)(Cl)Oc1cccc(NC(=O)c2ccnn2CCc2ccncc2)c1 Show InChI InChI=1S/C18H15ClF2N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211983
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Displacement of [32P]ATP from human VEGFR2 after 45 mins |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211992
(CHEMBL236419 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES FC(F)(Cl)Oc1cccc(NC(=O)c2ccnn2CCc2ccncc2)c1 Show InChI InChI=1S/C18H15ClF2N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Displacement of [32P]ATP from human VEGFR2 after 45 mins |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211976
(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-7-11-20-22(16)12-8-13-5-9-19-10-6-13/h1-7,9-11H,8,12H2,(H,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Displacement of [32P]ATP from human VEGFR2 after 45 mins |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211983
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211976
(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-7-11-20-22(16)12-8-13-5-9-19-10-6-13/h1-7,9-11H,8,12H2,(H,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211979
(CHEMBL399605 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-10-14-23-25(19)15-11-16-8-12-22-13-9-16/h4-10,12-14H,11,15H2,1-3H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211979
(CHEMBL399605 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-10-14-23-25(19)15-11-16-8-12-22-13-9-16/h4-10,12-14H,11,15H2,1-3H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Displacement of [32P]ATP from human VEGFR2 after 45 mins |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211972
(CHEMBL233823 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-11-13(1-2-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Displacement of [32P]ATP from human VEGFR2 after 45 mins |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211972
(CHEMBL233823 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-11-13(1-2-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211983
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211992
(CHEMBL236419 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES FC(F)(Cl)Oc1cccc(NC(=O)c2ccnn2CCc2ccncc2)c1 Show InChI InChI=1S/C18H15ClF2N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211983
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211979
(CHEMBL399605 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-10-14-23-25(19)15-11-16-8-12-22-13-9-16/h4-10,12-14H,11,15H2,1-3H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211979
(CHEMBL399605 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-10-14-23-25(19)15-11-16-8-12-22-13-9-16/h4-10,12-14H,11,15H2,1-3H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212000
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C18H15F3N4O/c19-18(20,21)14-1-3-15(4-2-14)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211981
(CHEMBL236420 | N-(4-isopropylphenyl)-1-(2-(pyridin...)Show InChI InChI=1S/C20H22N4O/c1-15(2)17-3-5-18(6-4-17)23-20(25)19-9-13-22-24(19)14-10-16-7-11-21-12-8-16/h3-9,11-13,15H,10,14H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212000
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C18H15F3N4O/c19-18(20,21)14-1-3-15(4-2-14)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211981
(CHEMBL236420 | N-(4-isopropylphenyl)-1-(2-(pyridin...)Show InChI InChI=1S/C20H22N4O/c1-15(2)17-3-5-18(6-4-17)23-20(25)19-9-13-22-24(19)14-10-16-7-11-21-12-8-16/h3-9,11-13,15H,10,14H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211976
(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-7-11-20-22(16)12-8-13-5-9-19-10-6-13/h1-7,9-11H,8,12H2,(H,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212010
(CHEMBL392935 | N-(4-ethylphenyl)-1-(2-(pyridin-4-y...)Show InChI InChI=1S/C19H20N4O/c1-2-15-3-5-17(6-4-15)22-19(24)18-9-13-21-23(18)14-10-16-7-11-20-12-8-16/h3-9,11-13H,2,10,14H2,1H3,(H,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211976
(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-7-11-20-22(16)12-8-13-5-9-19-10-6-13/h1-7,9-11H,8,12H2,(H,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211970
(CHEMBL234009 | N-(3,4-dimethoxyphenyl)-1-(2-(pyrid...)Show InChI InChI=1S/C19H20N4O3/c1-25-17-4-3-15(13-18(17)26-2)22-19(24)16-7-11-21-23(16)12-8-14-5-9-20-10-6-14/h3-7,9-11,13H,8,12H2,1-2H3,(H,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211972
(CHEMBL233823 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-11-13(1-2-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211976
(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-7-11-20-22(16)12-8-13-5-9-19-10-6-13/h1-7,9-11H,8,12H2,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211990
(CHEMBL392330 | N-(3,4-dichlorophenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C17H14Cl2N4O/c18-14-2-1-13(11-15(14)19)22-17(24)16-5-9-21-23(16)10-6-12-3-7-20-8-4-12/h1-5,7-9,11H,6,10H2,(H,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212010
(CHEMBL392935 | N-(4-ethylphenyl)-1-(2-(pyridin-4-y...)Show InChI InChI=1S/C19H20N4O/c1-2-15-3-5-17(6-4-15)22-19(24)18-9-13-21-23(18)14-10-16-7-11-20-12-8-16/h3-9,11-13H,2,10,14H2,1H3,(H,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211972
(CHEMBL233823 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-11-13(1-2-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211980
(1-(2-(pyridin-4-yl)ethyl)-N-(quinolin-3-yl)-1H-pyr...)Show InChI InChI=1S/C20H17N5O/c26-20(24-17-13-16-3-1-2-4-18(16)22-14-17)19-7-11-23-25(19)12-8-15-5-9-21-10-6-15/h1-7,9-11,13-14H,8,12H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211983
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212010
(CHEMBL392935 | N-(4-ethylphenyl)-1-(2-(pyridin-4-y...)Show InChI InChI=1S/C19H20N4O/c1-2-15-3-5-17(6-4-15)22-19(24)18-9-13-21-23(18)14-10-16-7-11-20-12-8-16/h3-9,11-13H,2,10,14H2,1H3,(H,22,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211990
(CHEMBL392330 | N-(3,4-dichlorophenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C17H14Cl2N4O/c18-14-2-1-13(11-15(14)19)22-17(24)16-5-9-21-23(16)10-6-12-3-7-20-8-4-12/h1-5,7-9,11H,6,10H2,(H,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211975
(1-(2-(pyridin-4-yl)ethyl)-N-(3-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211992
(CHEMBL236419 | N-(4-(chlorodifluoromethoxy)phenyl)...)Show SMILES FC(F)(Cl)Oc1cccc(NC(=O)c2ccnn2CCc2ccncc2)c1 Show InChI InChI=1S/C18H15ClF2N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211975
(1-(2-(pyridin-4-yl)ethyl)-N-(3-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 370 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212004
(CHEMBL234202 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-20-10-12-22(16)11-7-13-5-8-19-9-6-13/h1-6,8-10,12H,7,11H2,(H,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212000
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C18H15F3N4O/c19-18(20,21)14-1-3-15(4-2-14)24-17(26)16-7-11-23-25(16)12-8-13-5-9-22-10-6-13/h1-7,9-11H,8,12H2,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211980
(1-(2-(pyridin-4-yl)ethyl)-N-(quinolin-3-yl)-1H-pyr...)Show InChI InChI=1S/C20H17N5O/c26-20(24-17-13-16-3-1-2-4-18(16)22-14-17)19-7-11-23-25(19)12-8-15-5-9-21-10-6-15/h1-7,9-11,13-14H,8,12H2,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211970
(CHEMBL234009 | N-(3,4-dimethoxyphenyl)-1-(2-(pyrid...)Show InChI InChI=1S/C19H20N4O3/c1-25-17-4-3-15(13-18(17)26-2)22-19(24)16-7-11-21-23(16)12-8-14-5-9-20-10-6-14/h3-7,9-11,13H,8,12H2,1-2H3,(H,22,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211981
(CHEMBL236420 | N-(4-isopropylphenyl)-1-(2-(pyridin...)Show InChI InChI=1S/C20H22N4O/c1-15(2)17-3-5-18(6-4-17)23-20(25)19-9-13-22-24(19)14-10-16-7-11-21-12-8-16/h3-9,11-13,15H,10,14H2,1-2H3,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 440 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211991
(CHEMBL233822 | N-(4-chloro-3-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1cc(NC(=O)c2ccnn2CCc2ccncc2)ccc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-2-1-13(11-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211975
(1-(2-(pyridin-4-yl)ethyl)-N-(3-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-2-14(12-15)24-17(26)16-6-10-23-25(16)11-7-13-4-8-22-9-5-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211971
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C18H15F3N4O/c19-18(20,21)14-1-3-15(4-2-14)24-17(26)16-23-10-12-25(16)11-7-13-5-8-22-9-6-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211979
(CHEMBL399605 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-10-14-23-25(19)15-11-16-8-12-22-13-9-16/h4-10,12-14H,11,15H2,1-3H3,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 590 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211988
(CHEMBL393001 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C15H13ClN6O/c16-12-1-3-13(4-2-12)18-15(23)14-19-20-21-22(14)10-7-11-5-8-17-9-6-11/h1-6,8-9H,7,10H2,(H,18,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 640 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211991
(CHEMBL233822 | N-(4-chloro-3-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1cc(NC(=O)c2ccnn2CCc2ccncc2)ccc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-2-1-13(11-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211982
(CHEMBL234010 | N-(4-chlorophenyl)-3-methyl-1-(2-(p...)Show InChI InChI=1S/C18H17ClN4O/c1-13-12-17(18(24)21-16-4-2-15(19)3-5-16)23(22-13)11-8-14-6-9-20-10-7-14/h2-7,9-10,12H,8,11H2,1H3,(H,21,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211971
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C18H15F3N4O/c19-18(20,21)14-1-3-15(4-2-14)24-17(26)16-23-10-12-25(16)11-7-13-5-8-22-9-6-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211967
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-23-10-12-25(16)11-7-13-5-8-22-9-6-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212007
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C16H13F3N6O/c17-16(18,19)12-1-3-13(4-2-12)21-15(26)14-22-23-24-25(14)10-7-11-5-8-20-9-6-11/h1-6,8-9H,7,10H2,(H,21,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 850 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211990
(CHEMBL392330 | N-(3,4-dichlorophenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C17H14Cl2N4O/c18-14-2-1-13(11-15(14)19)22-17(24)16-5-9-21-23(16)10-6-12-3-7-20-8-4-12/h1-5,7-9,11H,6,10H2,(H,22,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211988
(CHEMBL393001 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C15H13ClN6O/c16-12-1-3-13(4-2-12)18-15(23)14-19-20-21-22(14)10-7-11-5-8-17-9-6-11/h1-6,8-9H,7,10H2,(H,18,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 890 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212008
(CHEMBL233824 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-23-13-15-25(19)14-10-16-8-11-22-12-9-16/h4-9,11-13,15H,10,14H2,1-3H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 940 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212004
(CHEMBL234202 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-20-10-12-22(16)11-7-13-5-8-19-9-6-13/h1-6,8-10,12H,7,11H2,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 940 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211973
(2-(2-pyridin-4-yl-ethyl)-2H-pyrazole-3-carboxylic ...)Show InChI InChI=1S/C23H20N4O/c28-23(22-12-16-25-27(22)17-13-18-10-14-24-15-11-18)26-21-8-6-20(7-9-21)19-4-2-1-3-5-19/h1-12,14-16H,13,17H2,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 950 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211972
(CHEMBL233823 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-11-13(1-2-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 980 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211967
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-23-10-12-25(16)11-7-13-5-8-22-9-6-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212007
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C16H13F3N6O/c17-16(18,19)12-1-3-13(4-2-12)21-15(26)14-22-23-24-25(14)10-7-11-5-8-20-9-6-11/h1-6,8-9H,7,10H2,(H,21,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.08E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211978
(3-methyl-1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoro...)Show SMILES Cc1cc(C(=O)Nc2ccc(OC(F)(F)F)cc2)n(CCc2ccncc2)n1 Show InChI InChI=1S/C19H17F3N4O2/c1-13-12-17(26(25-13)11-8-14-6-9-23-10-7-14)18(27)24-15-2-4-16(5-3-15)28-19(20,21)22/h2-7,9-10,12H,8,11H2,1H3,(H,24,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.19E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211980
(1-(2-(pyridin-4-yl)ethyl)-N-(quinolin-3-yl)-1H-pyr...)Show InChI InChI=1S/C20H17N5O/c26-20(24-17-13-16-3-1-2-4-18(16)22-14-17)19-7-11-23-25(19)12-8-15-5-9-21-10-6-15/h1-7,9-11,13-14H,8,12H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211982
(CHEMBL234010 | N-(4-chlorophenyl)-3-methyl-1-(2-(p...)Show InChI InChI=1S/C18H17ClN4O/c1-13-12-17(18(24)21-16-4-2-15(19)3-5-16)23(22-13)11-8-14-6-9-20-10-7-14/h2-7,9-10,12H,8,11H2,1H3,(H,21,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211970
(CHEMBL234009 | N-(3,4-dimethoxyphenyl)-1-(2-(pyrid...)Show InChI InChI=1S/C19H20N4O3/c1-25-17-4-3-15(13-18(17)26-2)22-19(24)16-7-11-21-23(16)12-8-14-5-9-20-10-6-14/h3-7,9-11,13H,8,12H2,1-2H3,(H,22,24) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.23E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211989
(CHEMBL233825 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2nccn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-11-13(1-2-14(15)18(20,21)22)25-17(27)16-24-8-10-26(16)9-5-12-3-6-23-7-4-12/h1-4,6-8,10-11H,5,9H2,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212004
(CHEMBL234202 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-1-3-15(4-2-14)21-17(23)16-20-10-12-22(16)11-7-13-5-8-19-9-6-13/h1-6,8-10,12H,7,11H2,(H,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211978
(3-methyl-1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoro...)Show SMILES Cc1cc(C(=O)Nc2ccc(OC(F)(F)F)cc2)n(CCc2ccncc2)n1 Show InChI InChI=1S/C19H17F3N4O2/c1-13-12-17(26(25-13)11-8-14-6-9-23-10-7-14)18(27)24-15-2-4-16(5-3-15)28-19(20,21)22/h2-7,9-10,12H,8,11H2,1H3,(H,24,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211973
(2-(2-pyridin-4-yl-ethyl)-2H-pyrazole-3-carboxylic ...)Show InChI InChI=1S/C23H20N4O/c28-23(22-12-16-25-27(22)17-13-18-10-14-24-15-11-18)26-21-8-6-20(7-9-21)19-4-2-1-3-5-19/h1-12,14-16H,13,17H2,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211971
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C18H15F3N4O/c19-18(20,21)14-1-3-15(4-2-14)24-17(26)16-23-10-12-25(16)11-7-13-5-8-22-9-6-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.66E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211988
(CHEMBL393001 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C15H13ClN6O/c16-12-1-3-13(4-2-12)18-15(23)14-19-20-21-22(14)10-7-11-5-8-17-9-6-11/h1-6,8-9H,7,10H2,(H,18,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211978
(3-methyl-1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoro...)Show SMILES Cc1cc(C(=O)Nc2ccc(OC(F)(F)F)cc2)n(CCc2ccncc2)n1 Show InChI InChI=1S/C19H17F3N4O2/c1-13-12-17(26(25-13)11-8-14-6-9-23-10-7-14)18(27)24-15-2-4-16(5-3-15)28-19(20,21)22/h2-7,9-10,12H,8,11H2,1H3,(H,24,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211973
(2-(2-pyridin-4-yl-ethyl)-2H-pyrazole-3-carboxylic ...)Show InChI InChI=1S/C23H20N4O/c28-23(22-12-16-25-27(22)17-13-18-10-14-24-15-11-18)26-21-8-6-20(7-9-21)19-4-2-1-3-5-19/h1-12,14-16H,13,17H2,(H,26,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212008
(CHEMBL233824 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-23-13-15-25(19)14-10-16-8-11-22-12-9-16/h4-9,11-13,15H,10,14H2,1-3H3,(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211991
(CHEMBL233822 | N-(4-chloro-3-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1cc(NC(=O)c2ccnn2CCc2ccncc2)ccc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-2-1-13(11-14(15)18(20,21)22)25-17(27)16-5-9-24-26(16)10-6-12-3-7-23-8-4-12/h1-5,7-9,11H,6,10H2,(H,25,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211982
(CHEMBL234010 | N-(4-chlorophenyl)-3-methyl-1-(2-(p...)Show InChI InChI=1S/C18H17ClN4O/c1-13-12-17(18(24)21-16-4-2-15(19)3-5-16)23(22-13)11-8-14-6-9-20-10-7-14/h2-7,9-10,12H,8,11H2,1H3,(H,21,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211996
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C16H13F3N6O2/c17-16(18,19)27-13-3-1-12(2-4-13)21-15(26)14-22-23-24-25(14)10-7-11-5-8-20-9-6-11/h1-6,8-9H,7,10H2,(H,21,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212007
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethyl)ph...)Show InChI InChI=1S/C16H13F3N6O/c17-16(18,19)12-1-3-13(4-2-12)21-15(26)14-22-23-24-25(14)10-7-11-5-8-20-9-6-11/h1-6,8-9H,7,10H2,(H,21,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211996
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C16H13F3N6O2/c17-16(18,19)27-13-3-1-12(2-4-13)21-15(26)14-22-23-24-25(14)10-7-11-5-8-20-9-6-11/h1-6,8-9H,7,10H2,(H,21,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212006
(CHEMBL392313 | N-(4-phenoxyphenyl)-1-(2-(pyridin-4...)Show InChI InChI=1S/C23H20N4O2/c28-23(22-12-16-25-27(22)17-13-18-10-14-24-15-11-18)26-19-6-8-21(9-7-19)29-20-4-2-1-3-5-20/h1-12,14-16H,13,17H2,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.22E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212008
(CHEMBL233824 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C21H24N4O/c1-21(2,3)17-4-6-18(7-5-17)24-20(26)19-23-13-15-25(19)14-10-16-8-11-22-12-9-16/h4-9,11-13,15H,10,14H2,1-3H3,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211996
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C16H13F3N6O2/c17-16(18,19)27-13-3-1-12(2-4-13)21-15(26)14-22-23-24-25(14)10-7-11-5-8-20-9-6-11/h1-6,8-9H,7,10H2,(H,21,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211967
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show InChI InChI=1S/C18H15F3N4O2/c19-18(20,21)27-15-3-1-14(2-4-15)24-17(26)16-23-10-12-25(16)11-7-13-5-8-22-9-6-13/h1-6,8-10,12H,7,11H2,(H,24,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.27E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211989
(CHEMBL233825 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2nccn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-11-13(1-2-14(15)18(20,21)22)25-17(27)16-24-8-10-26(16)9-5-12-3-6-23-7-4-12/h1-4,6-8,10-11H,5,9H2,(H,25,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211989
(CHEMBL233825 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2nccn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14ClF3N4O/c19-15-11-13(1-2-14(15)18(20,21)22)25-17(27)16-24-8-10-26(16)9-5-12-3-6-23-7-4-12/h1-4,6-8,10-11H,5,9H2,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211969
(CHEMBL233821 | N-(1H-indazol-5-yl)-1-(2-(pyridin-4...)Show InChI InChI=1S/C18H16N6O/c25-18(22-15-1-2-16-14(11-15)12-20-23-16)17-5-9-21-24(17)10-6-13-3-7-19-8-4-13/h1-5,7-9,11-12H,6,10H2,(H,20,23)(H,22,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212006
(CHEMBL392313 | N-(4-phenoxyphenyl)-1-(2-(pyridin-4...)Show InChI InChI=1S/C23H20N4O2/c28-23(22-12-16-25-27(22)17-13-18-10-14-24-15-11-18)26-19-6-8-21(9-7-19)29-20-4-2-1-3-5-20/h1-12,14-16H,13,17H2,(H,26,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211969
(CHEMBL233821 | N-(1H-indazol-5-yl)-1-(2-(pyridin-4...)Show InChI InChI=1S/C18H16N6O/c25-18(22-15-1-2-16-14(11-15)12-20-23-16)17-5-9-21-24(17)10-6-13-3-7-19-8-4-13/h1-5,7-9,11-12H,6,10H2,(H,20,23)(H,22,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211986
(3,4-dimethyl-1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifl...)Show SMILES Cc1nn(CCc2ccncc2)c(C(=O)Nc2ccc(OC(F)(F)F)cc2)c1C Show InChI InChI=1S/C20H19F3N4O2/c1-13-14(2)26-27(12-9-15-7-10-24-11-8-15)18(13)19(28)25-16-3-5-17(6-4-16)29-20(21,22)23/h3-8,10-11H,9,12H2,1-2H3,(H,25,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212002
(CHEMBL233631 | N-(4-(benzyloxy)phenyl)-1-(2-(pyrid...)Show SMILES O=C(Nc1ccc(OCc2ccccc2)cc1)c1ccnn1CCc1ccncc1 Show InChI InChI=1S/C24H22N4O2/c29-24(23-12-16-26-28(23)17-13-19-10-14-25-15-11-19)27-21-6-8-22(9-7-21)30-18-20-4-2-1-3-5-20/h1-12,14-16H,13,17-18H2,(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212003
(1-(3,4-difluorophenethyl)-N-(4-chlorophenyl)-1H-py...)Show InChI InChI=1S/C18H14ClF2N3O/c19-13-2-4-14(5-3-13)23-18(25)17-7-9-22-24(17)10-8-12-1-6-15(20)16(21)11-12/h1-7,9,11H,8,10H2,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211974
(CHEMBL233826 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C21H17ClN4O/c22-16-5-7-17(8-6-16)24-21(27)20-25-18-3-1-2-4-19(18)26(20)14-11-15-9-12-23-13-10-15/h1-10,12-13H,11,14H2,(H,24,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211998
(CHEMBL234013 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2nc3ccccc3n2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C22H16ClF3N4O/c23-17-13-15(5-6-16(17)22(24,25)26)28-21(31)20-29-18-3-1-2-4-19(18)30(20)12-9-14-7-10-27-11-8-14/h1-8,10-11,13H,9,12H2,(H,28,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211985
(CHEMBL234863 | N-(4-chlorophenyl)-1-(2-(6-methyl-5...)Show SMILES CC1CC(CCn2nccc2C(=O)Nc2ccc(Cl)cc2)=C2OCOC2=C1 |w:1.0,c:28,t:22| Show InChI InChI=1S/C20H20ClN3O3/c1-13-10-14(19-18(11-13)26-12-27-19)7-9-24-17(6-8-22-24)20(25)23-16-4-2-15(21)3-5-16/h2-6,8,11,13H,7,9-10,12H2,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211995
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show SMILES FC(F)(F)Oc1ccc(NC(=O)c2nc3ccccc3n2CCc2ccncc2)cc1 Show InChI InChI=1S/C22H17F3N4O2/c23-22(24,25)31-17-7-5-16(6-8-17)27-21(30)20-28-18-3-1-2-4-19(18)29(20)14-11-15-9-12-26-13-10-15/h1-10,12-13H,11,14H2,(H,27,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211968
(CHEMBL391102 | N-(4-chlorophenyl)-3,4-dimethyl-1-(...)Show InChI InChI=1S/C19H19ClN4O/c1-13-14(2)23-24(12-9-15-7-10-21-11-8-15)18(13)19(25)22-17-5-3-16(20)4-6-17/h3-8,10-11H,9,12H2,1-2H3,(H,22,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211969
(CHEMBL233821 | N-(1H-indazol-5-yl)-1-(2-(pyridin-4...)Show InChI InChI=1S/C18H16N6O/c25-18(22-15-1-2-16-14(11-15)12-20-23-16)17-5-9-21-24(17)10-6-13-3-7-19-8-4-13/h1-5,7-9,11-12H,6,10H2,(H,20,23)(H,22,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211977
(CHEMBL392329 | N-(1H-indazol-6-yl)-1-(2-(pyridin-4...)Show InChI InChI=1S/C18H16N6O/c25-18(22-15-2-1-14-12-20-23-16(14)11-15)17-5-9-21-24(17)10-6-13-3-7-19-8-4-13/h1-5,7-9,11-12H,6,10H2,(H,20,23)(H,22,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211994
(CHEMBL397322 | N-(4-chlorophenyl)-1-(2-(pyridin-3-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-3-5-15(6-4-14)21-17(23)16-7-10-20-22(16)11-8-13-2-1-9-19-12-13/h1-7,9-10,12H,8,11H2,(H,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212001
(CHEMBL233829 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2nnnn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C16H12ClF3N6O/c17-13-9-11(1-2-12(13)16(18,19)20)22-15(27)14-23-24-25-26(14)8-5-10-3-6-21-7-4-10/h1-4,6-7,9H,5,8H2,(H,22,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211993
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show SMILES FC(F)(F)Oc1ccc(NC(=O)c2cc3ccccc3n2CCc2ccncc2)cc1 Show InChI InChI=1S/C23H18F3N3O2/c24-23(25,26)31-19-7-5-18(6-8-19)28-22(30)21-15-17-3-1-2-4-20(17)29(21)14-11-16-9-12-27-13-10-16/h1-10,12-13,15H,11,14H2,(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211968
(CHEMBL391102 | N-(4-chlorophenyl)-3,4-dimethyl-1-(...)Show InChI InChI=1S/C19H19ClN4O/c1-13-14(2)23-24(12-9-15-7-10-21-11-8-15)18(13)19(25)22-17-5-3-16(20)4-6-17/h3-8,10-11H,9,12H2,1-2H3,(H,22,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212003
(1-(3,4-difluorophenethyl)-N-(4-chlorophenyl)-1H-py...)Show InChI InChI=1S/C18H14ClF2N3O/c19-13-2-4-14(5-3-13)23-18(25)17-7-9-22-24(17)10-8-12-1-6-15(20)16(21)11-12/h1-7,9,11H,8,10H2,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211994
(CHEMBL397322 | N-(4-chlorophenyl)-1-(2-(pyridin-3-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-3-5-15(6-4-14)21-17(23)16-7-10-20-22(16)11-8-13-2-1-9-19-12-13/h1-7,9-10,12H,8,11H2,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211986
(3,4-dimethyl-1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifl...)Show SMILES Cc1nn(CCc2ccncc2)c(C(=O)Nc2ccc(OC(F)(F)F)cc2)c1C Show InChI InChI=1S/C20H19F3N4O2/c1-13-14(2)26-27(12-9-15-7-10-24-11-8-15)18(13)19(28)25-16-3-5-17(6-4-16)29-20(21,22)23/h3-8,10-11H,9,12H2,1-2H3,(H,25,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211995
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show SMILES FC(F)(F)Oc1ccc(NC(=O)c2nc3ccccc3n2CCc2ccncc2)cc1 Show InChI InChI=1S/C22H17F3N4O2/c23-22(24,25)31-17-7-5-16(6-8-17)27-21(30)20-28-18-3-1-2-4-19(18)29(20)14-11-15-9-12-26-13-10-15/h1-10,12-13H,11,14H2,(H,27,30) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211977
(CHEMBL392329 | N-(1H-indazol-6-yl)-1-(2-(pyridin-4...)Show InChI InChI=1S/C18H16N6O/c25-18(22-15-2-1-14-12-20-23-16(14)11-15)17-5-9-21-24(17)10-6-13-3-7-19-8-4-13/h1-5,7-9,11-12H,6,10H2,(H,20,23)(H,22,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211999
(1-(2-(benzo[d]isoxazol-3-yl)ethyl)-N-(4-chlorophen...)Show InChI InChI=1S/C19H15ClN4O2/c20-13-5-7-14(8-6-13)22-19(25)17-9-11-21-24(17)12-10-16-15-3-1-2-4-18(15)26-23-16/h1-9,11H,10,12H2,(H,22,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211994
(CHEMBL397322 | N-(4-chlorophenyl)-1-(2-(pyridin-3-...)Show InChI InChI=1S/C17H15ClN4O/c18-14-3-5-15(6-4-14)21-17(23)16-7-10-20-22(16)11-8-13-2-1-9-19-12-13/h1-7,9-10,12H,8,11H2,(H,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212011
(1-(3,4-dimethoxyphenethyl)-N-(4-chlorophenyl)-1H-p...)Show InChI InChI=1S/C20H20ClN3O3/c1-26-18-8-3-14(13-19(18)27-2)10-12-24-17(9-11-22-24)20(25)23-16-6-4-15(21)5-7-16/h3-9,11,13H,10,12H2,1-2H3,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211986
(3,4-dimethyl-1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifl...)Show SMILES Cc1nn(CCc2ccncc2)c(C(=O)Nc2ccc(OC(F)(F)F)cc2)c1C Show InChI InChI=1S/C20H19F3N4O2/c1-13-14(2)26-27(12-9-15-7-10-24-11-8-15)18(13)19(28)25-16-3-5-17(6-4-16)29-20(21,22)23/h3-8,10-11H,9,12H2,1-2H3,(H,25,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212001
(CHEMBL233829 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2nnnn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C16H12ClF3N6O/c17-13-9-11(1-2-12(13)16(18,19)20)22-15(27)14-23-24-25-26(14)8-5-10-3-6-21-7-4-10/h1-4,6-7,9H,5,8H2,(H,22,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211966
(CHEMBL234201 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C22H18ClN3O/c23-18-5-7-19(8-6-18)25-22(27)21-15-17-3-1-2-4-20(17)26(21)14-11-16-9-12-24-13-10-16/h1-10,12-13,15H,11,14H2,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211984
(CHEMBL232800 | N-(4-chlorophenyl)-1-(2-(pyridin-2-...)Show InChI InChI=1S/C17H15ClN4O/c18-13-4-6-15(7-5-13)21-17(23)16-8-11-20-22(16)12-9-14-3-1-2-10-19-14/h1-8,10-11H,9,12H2,(H,21,23) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212009
(CHEMBL395824 | N-(4-chlorophenyl)-N-methyl-1-(2-(p...)Show InChI InChI=1S/C18H17ClN4O/c1-22(16-4-2-15(19)3-5-16)18(24)17-8-12-21-23(17)13-9-14-6-10-20-11-7-14/h2-8,10-12H,9,13H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212006
(CHEMBL392313 | N-(4-phenoxyphenyl)-1-(2-(pyridin-4...)Show InChI InChI=1S/C23H20N4O2/c28-23(22-12-16-25-27(22)17-13-18-10-14-24-15-11-18)26-19-6-8-21(9-7-19)29-20-4-2-1-3-5-20/h1-12,14-16H,13,17H2,(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211987
(1-(2-(1H-imidazol-4-yl)ethyl)-N-(4-chlorophenyl)-1...)Show InChI InChI=1S/C15H14ClN5O/c16-11-1-3-12(4-2-11)20-15(22)14-5-7-19-21(14)8-6-13-9-17-10-18-13/h1-5,7,9-10H,6,8H2,(H,17,18)(H,20,22) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211998
(CHEMBL234013 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2nc3ccccc3n2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C22H16ClF3N4O/c23-17-13-15(5-6-16(17)22(24,25)26)28-21(31)20-29-18-3-1-2-4-19(18)30(20)12-9-14-7-10-27-11-8-14/h1-8,10-11,13H,9,12H2,(H,28,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211993
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show SMILES FC(F)(F)Oc1ccc(NC(=O)c2cc3ccccc3n2CCc2ccncc2)cc1 Show InChI InChI=1S/C23H18F3N3O2/c24-23(25,26)31-19-7-5-18(6-8-19)28-22(30)21-15-17-3-1-2-4-20(17)29(21)14-11-16-9-12-27-13-10-16/h1-10,12-13,15H,11,14H2,(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212005
(CHEMBL232802 | N-(4-chlorophenyl)-1-(2-(isoxazol-4...)Show InChI InChI=1S/C15H13ClN4O2/c16-12-1-3-13(4-2-12)19-15(21)14-5-7-17-20(14)8-6-11-9-18-22-10-11/h1-5,7,9-10H,6,8H2,(H,19,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211997
(CHEMBL233828 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C19H22N6O/c1-19(2,3)15-4-6-16(7-5-15)21-18(26)17-22-23-24-25(17)13-10-14-8-11-20-12-9-14/h4-9,11-12H,10,13H2,1-3H3,(H,21,26) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212009
(CHEMBL395824 | N-(4-chlorophenyl)-N-methyl-1-(2-(p...)Show InChI InChI=1S/C18H17ClN4O/c1-22(16-4-2-15(19)3-5-16)18(24)17-8-12-21-23(17)13-9-14-6-10-20-11-7-14/h2-8,10-12H,9,13H2,1H3 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212002
(CHEMBL233631 | N-(4-(benzyloxy)phenyl)-1-(2-(pyrid...)Show SMILES O=C(Nc1ccc(OCc2ccccc2)cc1)c1ccnn1CCc1ccncc1 Show InChI InChI=1S/C24H22N4O2/c29-24(23-12-16-26-28(23)17-13-19-10-14-25-15-11-19)27-21-6-8-22(9-7-21)30-18-20-4-2-1-3-5-20/h1-12,14-16H,13,17-18H2,(H,27,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212002
(CHEMBL233631 | N-(4-(benzyloxy)phenyl)-1-(2-(pyrid...)Show SMILES O=C(Nc1ccc(OCc2ccccc2)cc1)c1ccnn1CCc1ccncc1 Show InChI InChI=1S/C24H22N4O2/c29-24(23-12-16-26-28(23)17-13-19-10-14-25-15-11-19)27-21-6-8-22(9-7-21)30-18-20-4-2-1-3-5-20/h1-12,14-16H,13,17-18H2,(H,27,29) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211984
(CHEMBL232800 | N-(4-chlorophenyl)-1-(2-(pyridin-2-...)Show InChI InChI=1S/C17H15ClN4O/c18-13-4-6-15(7-5-13)21-17(23)16-8-11-20-22(16)12-9-14-3-1-2-10-19-14/h1-8,10-11H,9,12H2,(H,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211977
(CHEMBL392329 | N-(1H-indazol-6-yl)-1-(2-(pyridin-4...)Show InChI InChI=1S/C18H16N6O/c25-18(22-15-2-1-14-12-20-23-16(14)11-15)17-5-9-21-24(17)10-6-13-3-7-19-8-4-13/h1-5,7-9,11-12H,6,10H2,(H,20,23)(H,22,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211999
(1-(2-(benzo[d]isoxazol-3-yl)ethyl)-N-(4-chlorophen...)Show InChI InChI=1S/C19H15ClN4O2/c20-13-5-7-14(8-6-13)22-19(25)17-9-11-21-24(17)12-10-16-15-3-1-2-4-18(15)26-23-16/h1-9,11H,10,12H2,(H,22,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211966
(CHEMBL234201 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C22H18ClN3O/c23-18-5-7-19(8-6-18)25-22(27)21-15-17-3-1-2-4-20(17)26(21)14-11-16-9-12-24-13-10-16/h1-10,12-13,15H,11,14H2,(H,25,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211985
(CHEMBL234863 | N-(4-chlorophenyl)-1-(2-(6-methyl-5...)Show SMILES CC1CC(CCn2nccc2C(=O)Nc2ccc(Cl)cc2)=C2OCOC2=C1 |w:1.0,c:28,t:22| Show InChI InChI=1S/C20H20ClN3O3/c1-13-10-14(19-18(11-13)26-12-27-19)7-9-24-17(6-8-22-24)20(25)23-16-4-2-15(21)3-5-16/h2-6,8,11,13H,7,9-10,12H2,1H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211997
(CHEMBL233828 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C19H22N6O/c1-19(2,3)15-4-6-16(7-5-15)21-18(26)17-22-23-24-25(17)13-10-14-8-11-20-12-9-14/h4-9,11-12H,10,13H2,1-3H3,(H,21,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212011
(1-(3,4-dimethoxyphenethyl)-N-(4-chlorophenyl)-1H-p...)Show InChI InChI=1S/C20H20ClN3O3/c1-26-18-8-3-14(13-19(18)27-2)10-12-24-17(9-11-22-24)20(25)23-16-6-4-15(21)5-7-16/h3-9,11,13H,10,12H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211999
(1-(2-(benzo[d]isoxazol-3-yl)ethyl)-N-(4-chlorophen...)Show InChI InChI=1S/C19H15ClN4O2/c20-13-5-7-14(8-6-13)22-19(25)17-9-11-21-24(17)12-10-16-15-3-1-2-4-18(15)26-23-16/h1-9,11H,10,12H2,(H,22,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211968
(CHEMBL391102 | N-(4-chlorophenyl)-3,4-dimethyl-1-(...)Show InChI InChI=1S/C19H19ClN4O/c1-13-14(2)23-24(12-9-15-7-10-21-11-8-15)18(13)19(25)22-17-5-3-16(20)4-6-17/h3-8,10-11H,9,12H2,1-2H3,(H,22,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211984
(CHEMBL232800 | N-(4-chlorophenyl)-1-(2-(pyridin-2-...)Show InChI InChI=1S/C17H15ClN4O/c18-13-4-6-15(7-5-13)21-17(23)16-8-11-20-22(16)12-9-14-3-1-2-10-19-14/h1-8,10-11H,9,12H2,(H,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211993
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show SMILES FC(F)(F)Oc1ccc(NC(=O)c2cc3ccccc3n2CCc2ccncc2)cc1 Show InChI InChI=1S/C23H18F3N3O2/c24-23(25,26)31-19-7-5-18(6-8-19)28-22(30)21-15-17-3-1-2-4-20(17)29(21)14-11-16-9-12-27-13-10-16/h1-10,12-13,15H,11,14H2,(H,28,30) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211997
(CHEMBL233828 | N-(4-tert-butylphenyl)-1-(2-(pyridi...)Show InChI InChI=1S/C19H22N6O/c1-19(2,3)15-4-6-16(7-5-15)21-18(26)17-22-23-24-25(17)13-10-14-8-11-20-12-9-14/h4-9,11-12H,10,13H2,1-3H3,(H,21,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211995
(1-(2-(pyridin-4-yl)ethyl)-N-(4-(trifluoromethoxy)p...)Show SMILES FC(F)(F)Oc1ccc(NC(=O)c2nc3ccccc3n2CCc2ccncc2)cc1 Show InChI InChI=1S/C22H17F3N4O2/c23-22(24,25)31-17-7-5-16(6-8-17)27-21(30)20-28-18-3-1-2-4-19(18)29(20)14-11-15-9-12-26-13-10-15/h1-10,12-13H,11,14H2,(H,27,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211987
(1-(2-(1H-imidazol-4-yl)ethyl)-N-(4-chlorophenyl)-1...)Show InChI InChI=1S/C15H14ClN5O/c16-11-1-3-12(4-2-11)20-15(22)14-5-7-19-21(14)8-6-13-9-17-10-18-13/h1-5,7,9-10H,6,8H2,(H,17,18)(H,20,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212005
(CHEMBL232802 | N-(4-chlorophenyl)-1-(2-(isoxazol-4...)Show InChI InChI=1S/C15H13ClN4O2/c16-12-1-3-13(4-2-12)19-15(21)14-5-7-17-20(14)8-6-11-9-18-22-10-11/h1-5,7,9-10H,6,8H2,(H,19,21) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212003
(1-(3,4-difluorophenethyl)-N-(4-chlorophenyl)-1H-py...)Show InChI InChI=1S/C18H14ClF2N3O/c19-13-2-4-14(5-3-13)23-18(25)17-7-9-22-24(17)10-8-12-1-6-15(20)16(21)11-12/h1-7,9,11H,8,10H2,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211966
(CHEMBL234201 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C22H18ClN3O/c23-18-5-7-19(8-6-18)25-22(27)21-15-17-3-1-2-4-20(17)26(21)14-11-16-9-12-24-13-10-16/h1-10,12-13,15H,11,14H2,(H,25,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211974
(CHEMBL233826 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C21H17ClN4O/c22-16-5-7-17(8-6-16)24-21(27)20-25-18-3-1-2-4-19(18)26(20)14-11-15-9-12-23-13-10-15/h1-10,12-13H,11,14H2,(H,24,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211985
(CHEMBL234863 | N-(4-chlorophenyl)-1-(2-(6-methyl-5...)Show SMILES CC1CC(CCn2nccc2C(=O)Nc2ccc(Cl)cc2)=C2OCOC2=C1 |w:1.0,c:28,t:22| Show InChI InChI=1S/C20H20ClN3O3/c1-13-10-14(19-18(11-13)26-12-27-19)7-9-24-17(6-8-22-24)20(25)23-16-4-2-15(21)3-5-16/h2-6,8,11,13H,7,9-10,12H2,1H3,(H,23,25) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211987
(1-(2-(1H-imidazol-4-yl)ethyl)-N-(4-chlorophenyl)-1...)Show InChI InChI=1S/C15H14ClN5O/c16-11-1-3-12(4-2-11)20-15(22)14-5-7-19-21(14)8-6-13-9-17-10-18-13/h1-5,7,9-10H,6,8H2,(H,17,18)(H,20,22) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50211998
(CHEMBL234013 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2nc3ccccc3n2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C22H16ClF3N4O/c23-17-13-15(5-6-16(17)22(24,25)26)28-21(31)20-29-18-3-1-2-4-19(18)30(20)12-9-14-7-10-27-11-8-14/h1-8,10-11,13H,9,12H2,(H,28,31) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212001
(CHEMBL233829 | N-(3-chloro-4-(trifluoromethyl)phen...)Show SMILES FC(F)(F)c1ccc(NC(=O)c2nnnn2CCc2ccncc2)cc1Cl Show InChI InChI=1S/C16H12ClF3N6O/c17-13-9-11(1-2-12(13)16(18,19)20)22-15(27)14-23-24-25-26(14)8-5-10-3-6-21-7-4-10/h1-4,6-7,9H,5,8H2,(H,22,27) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM50212005
(CHEMBL232802 | N-(4-chlorophenyl)-1-(2-(isoxazol-4...)Show InChI InChI=1S/C15H13ClN4O2/c16-12-1-3-13(4-2-12)19-15(21)14-5-7-17-20(14)8-6-11-9-18-22-10-11/h1-5,7,9-10H,6,8H2,(H,19,21) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50212011
(1-(3,4-dimethoxyphenethyl)-N-(4-chlorophenyl)-1H-p...)Show InChI InChI=1S/C20H20ClN3O3/c1-26-18-8-3-14(13-19(18)27-2)10-12-24-17(9-11-22-24)20(25)23-16-6-4-15(21)5-7-16/h3-9,11,13H,10,12H2,1-2H3,(H,23,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISA |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50211974
(CHEMBL233826 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)Show InChI InChI=1S/C21H17ClN4O/c22-16-5-7-17(8-6-16)24-21(27)20-25-18-3-1-2-4-19(18)26(20)14-11-15-9-12-23-13-10-15/h1-10,12-13H,11,14H2,(H,24,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chemical Diversity, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assay |
Bioorg Med Chem Lett 17: 3550-7 (2007)
Article DOI: 10.1016/j.bmcl.2007.04.042
BindingDB Entry DOI: 10.7270/Q2MG7P6N |
More data for this
Ligand-Target Pair | |
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