Found 95 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213387
(CHEMBL393965 | ethyl 4-(1-(4-(methoxycarbonyl)benz...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(cc1)C(=O)OC)c1ccccc1 Show InChI InChI=1S/C26H29N3O4/c1-3-33-25(31)28-16-13-26(14-17-28,22-7-5-4-6-8-22)24-27-15-18-29(24)19-20-9-11-21(12-10-20)23(30)32-2/h4-12,15,18H,3,13-14,16-17,19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 0.740 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213393
(CHEMBL232548 | methyl 4-((2-(1-benzoyl-4-phenylpip...)Show SMILES COC(=O)c1ccc(Cn2ccnc2C2(CCN(CC2)C(=O)c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C30H29N3O3/c1-36-28(35)25-14-12-23(13-15-25)22-33-21-18-31-29(33)30(26-10-6-3-7-11-26)16-19-32(20-17-30)27(34)24-8-4-2-5-9-24/h2-15,18,21H,16-17,19-20,22H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 0.930 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213403
(CHEMBL391852 | ethyl 4-phenyl-4-(1-(1-phenylethyl)...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1C(C)c1ccccc1)c1ccccc1 |w:16.18| Show InChI InChI=1S/C25H29N3O2/c1-3-30-24(29)27-17-14-25(15-18-27,22-12-8-5-9-13-22)23-26-16-19-28(23)20(2)21-10-6-4-7-11-21/h4-13,16,19-20H,3,14-15,17-18H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213380
(CHEMBL400436 | isopropyl 4-(1-benzyl-1H-imidazol-2...)Show SMILES CC(C)OC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O2/c1-20(2)30-24(29)27-16-13-25(14-17-27,22-11-7-4-8-12-22)23-26-15-18-28(23)19-21-9-5-3-6-10-21/h3-12,15,18,20H,13-14,16-17,19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213404
((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...)Show SMILES O=C(N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H27N3O/c32-26(24-12-6-2-7-13-24)30-19-16-28(17-20-30,25-14-8-3-9-15-25)27-29-18-21-31(27)22-23-10-4-1-5-11-23/h1-15,18,21H,16-17,19-20,22H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213374
(CHEMBL437397 | phenyl(4-phenyl-4-(1-(1-phenylethyl...)Show SMILES CC(c1ccccc1)n1ccnc1C1(CCN(CC1)C(=O)c1ccccc1)c1ccccc1 |w:1.0| Show InChI InChI=1S/C29H29N3O/c1-23(24-11-5-2-6-12-24)32-22-19-30-28(32)29(26-15-9-4-10-16-26)17-20-31(21-18-29)27(33)25-13-7-3-8-14-25/h2-16,19,22-23H,17-18,20-21H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213372
(CHEMBL399205 | propyl 4-(1-benzyl-1H-imidazol-2-yl...)Show SMILES CCCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O2/c1-2-19-30-24(29)27-16-13-25(14-17-27,22-11-7-4-8-12-22)23-26-15-18-28(23)20-21-9-5-3-6-10-21/h3-12,15,18H,2,13-14,16-17,19-20H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213406
(CHEMBL232740 | ethyl 4-(1-benzyl-1H-imidazol-2-yl)...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O2/c1-2-29-23(28)26-16-13-24(14-17-26,21-11-7-4-8-12-21)22-25-15-18-27(22)19-20-9-5-3-6-10-20/h3-12,15,18H,2,13-14,16-17,19H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213376
(2-methoxy-1-(4-phenyl-4-(1-(1-phenylethyl)-1H-imid...)Show SMILES COCC(=O)N1CCC(CC1)(c1nccn1C(C)c1ccccc1)c1ccccc1 |w:16.18| Show InChI InChI=1S/C25H29N3O2/c1-20(21-9-5-3-6-10-21)28-18-15-26-24(28)25(22-11-7-4-8-12-22)13-16-27(17-14-25)23(29)19-30-2/h3-12,15,18,20H,13-14,16-17,19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213400
(CHEMBL391623 | ethyl 4-(1-(4-hydroxybenzyl)-1H-imi...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(O)cc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O3/c1-2-30-23(29)26-15-12-24(13-16-26,20-6-4-3-5-7-20)22-25-14-17-27(22)18-19-8-10-21(28)11-9-19/h3-11,14,17,28H,2,12-13,15-16,18H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213381
(CHEMBL232137 | methyl 4-((2-(1-(2-methoxyacetyl)-4...)Show SMILES COCC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(cc1)C(=O)OC)c1ccccc1 Show InChI InChI=1S/C26H29N3O4/c1-32-19-23(30)28-15-12-26(13-16-28,22-6-4-3-5-7-22)25-27-14-17-29(25)18-20-8-10-21(11-9-20)24(31)33-2/h3-11,14,17H,12-13,15-16,18-19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213397
(CHEMBL231783 | ethyl 4-(1-(3-fluorobenzyl)-1H-imid...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1cccc(F)c1)c1ccccc1 Show InChI InChI=1S/C24H26FN3O2/c1-2-30-23(29)27-14-11-24(12-15-27,20-8-4-3-5-9-20)22-26-13-16-28(22)18-19-7-6-10-21(25)17-19/h3-10,13,16-17H,2,11-12,14-15,18H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213386
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show SMILES COCC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O2/c1-29-19-22(28)26-15-12-24(13-16-26,21-10-6-3-7-11-21)23-25-14-17-27(23)18-20-8-4-2-5-9-20/h2-11,14,17H,12-13,15-16,18-19H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213378
(CHEMBL233143 | cyclohexyl 4-(1-benzyl-1H-imidazol-...)Show SMILES O=C(OC1CCCCC1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H33N3O2/c32-27(33-25-14-8-3-9-15-25)30-19-16-28(17-20-30,24-12-6-2-7-13-24)26-29-18-21-31(26)22-23-10-4-1-5-11-23/h1-2,4-7,10-13,18,21,25H,3,8-9,14-17,19-20,22H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213390
(CHEMBL392266 | tert-butyl 4-(1-benzyl-1H-imidazol-...)Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H31N3O2/c1-25(2,3)31-24(30)28-17-14-26(15-18-28,22-12-8-5-9-13-22)23-27-16-19-29(23)20-21-10-6-4-7-11-21/h4-13,16,19H,14-15,17-18,20H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213398
(CHEMBL232937 | butyl 4-(1-benzyl-1H-imidazol-2-yl)...)Show SMILES CCCCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H31N3O2/c1-2-3-20-31-25(30)28-17-14-26(15-18-28,23-12-8-5-9-13-23)24-27-16-19-29(24)21-22-10-6-4-7-11-22/h4-13,16,19H,2-3,14-15,17-18,20-21H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 9.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213395
(CHEMBL231781 | ethyl 4-(1-(4-methoxybenzyl)-1H-imi...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(OC)cc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O3/c1-3-31-24(29)27-16-13-25(14-17-27,21-7-5-4-6-8-21)23-26-15-18-28(23)19-20-9-11-22(30-2)12-10-20/h4-12,15,18H,3,13-14,16-17,19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213394
(CHEMBL233368 | benzyl 4-(1-benzyl-1H-imidazol-2-yl...)Show SMILES O=C(OCc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H29N3O2/c33-28(34-23-25-12-6-2-7-13-25)31-19-16-29(17-20-31,26-14-8-3-9-15-26)27-30-18-21-32(27)22-24-10-4-1-5-11-24/h1-15,18,21H,16-17,19-20,22-23H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213377
(CHEMBL232738 | methyl 4-(1-benzyl-1H-imidazol-2-yl...)Show SMILES COC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N3O2/c1-28-22(27)25-15-12-23(13-16-25,20-10-6-3-7-11-20)21-24-14-17-26(21)18-19-8-4-2-5-9-19/h2-11,14,17H,12-13,15-16,18H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213389
((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...)Show SMILES O=C(C1CC1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H27N3O/c29-23(21-11-12-21)27-16-13-25(14-17-27,22-9-5-2-6-10-22)24-26-15-18-28(24)19-20-7-3-1-4-8-20/h1-10,15,18,21H,11-14,16-17,19H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213384
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show SMILES O=C(Cc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H29N3O/c33-27(22-24-10-4-1-5-11-24)31-19-16-29(17-20-31,26-14-8-3-9-15-26)28-30-18-21-32(28)23-25-12-6-2-7-13-25/h1-15,18,21H,16-17,19-20,22-23H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213387
(CHEMBL393965 | ethyl 4-(1-(4-(methoxycarbonyl)benz...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(cc1)C(=O)OC)c1ccccc1 Show InChI InChI=1S/C26H29N3O4/c1-3-33-25(31)28-16-13-26(14-17-28,22-7-5-4-6-8-22)24-27-15-18-29(24)19-20-9-11-21(12-10-20)23(30)32-2/h4-12,15,18H,3,13-14,16-17,19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213405
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show SMILES CCC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O/c1-2-22(28)26-16-13-24(14-17-26,21-11-7-4-8-12-21)23-25-15-18-27(23)19-20-9-5-3-6-10-20/h3-12,15,18H,2,13-14,16-17,19H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213388
(CHEMBL233570 | ethyl 4-(1-(3-methoxybenzyl)-1H-imi...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1cccc(OC)c1)c1ccccc1 Show InChI InChI=1S/C25H29N3O3/c1-3-31-24(29)27-15-12-25(13-16-27,21-9-5-4-6-10-21)23-26-14-17-28(23)19-20-8-7-11-22(18-20)30-2/h4-11,14,17-18H,3,12-13,15-16,19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213391
((3,5-bis(trifluoromethyl)phenyl)(4-(1-benzyl-1H-im...)Show SMILES FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H25F6N3O/c31-29(32,33)24-17-22(18-25(19-24)30(34,35)36)26(40)38-14-11-28(12-15-38,23-9-5-2-6-10-23)27-37-13-16-39(27)20-21-7-3-1-4-8-21/h1-10,13,16-19H,11-12,14-15,20H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213373
((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...)Show SMILES Cc1cc(C)cc(c1)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H31N3O/c1-23-19-24(2)21-26(20-23)28(34)32-16-13-30(14-17-32,27-11-7-4-8-12-27)29-31-15-18-33(29)22-25-9-5-3-6-10-25/h3-12,15,18-21H,13-14,16-17,22H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213379
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show InChI InChI=1S/C23H25N3O/c1-19(27)25-15-12-23(13-16-25,21-10-6-3-7-11-21)22-24-14-17-26(22)18-20-8-4-2-5-9-20/h2-11,14,17H,12-13,15-16,18H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213407
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show SMILES CC(C)(C)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H31N3O/c1-25(2,3)24(30)28-17-14-26(15-18-28,22-12-8-5-9-13-22)23-27-16-19-29(23)20-21-10-6-4-7-11-21/h4-13,16,19H,14-15,17-18,20H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213392
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show SMILES CC(C)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O/c1-20(2)23(29)27-16-13-25(14-17-27,22-11-7-4-8-12-22)24-26-15-18-28(24)19-21-9-5-3-6-10-21/h3-12,15,18,20H,13-14,16-17,19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213385
(CHEMBL233427 | ethyl 4-(1-(4-fluorobenzyl)-1H-imid...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C24H26FN3O2/c1-2-30-23(29)27-15-12-24(13-16-27,20-6-4-3-5-7-20)22-26-14-17-28(22)18-19-8-10-21(25)11-9-19/h3-11,14,17H,2,12-13,15-16,18H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213403
(CHEMBL391852 | ethyl 4-phenyl-4-(1-(1-phenylethyl)...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1C(C)c1ccccc1)c1ccccc1 |w:16.18| Show InChI InChI=1S/C25H29N3O2/c1-3-30-24(29)27-17-14-25(15-18-27,22-12-8-5-9-13-22)23-26-16-19-28(23)20(2)21-10-6-4-7-11-21/h4-13,16,19-20H,3,14-15,17-18H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 62 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213381
(CHEMBL232137 | methyl 4-((2-(1-(2-methoxyacetyl)-4...)Show SMILES COCC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(cc1)C(=O)OC)c1ccccc1 Show InChI InChI=1S/C26H29N3O4/c1-32-19-23(30)28-15-12-26(13-16-28,22-6-4-3-5-7-22)25-27-14-17-29(25)18-20-8-10-21(11-9-20)24(31)33-2/h3-11,14,17H,12-13,15-16,18-19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213390
(CHEMBL392266 | tert-butyl 4-(1-benzyl-1H-imidazol-...)Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H31N3O2/c1-25(2,3)31-24(30)28-17-14-26(15-18-28,22-12-8-5-9-13-22)23-27-16-19-29(23)20-21-10-6-4-7-11-21/h4-13,16,19H,14-15,17-18,20H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 84 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213396
(CHEMBL232345 | methyl 3-((2-(1-benzoyl-4-phenylpip...)Show SMILES COC(=O)c1cccc(Cn2ccnc2C2(CCN(CC2)C(=O)c2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C30H29N3O3/c1-36-28(35)25-12-8-9-23(21-25)22-33-20-17-31-29(33)30(26-13-6-3-7-14-26)15-18-32(19-16-30)27(34)24-10-4-2-5-11-24/h2-14,17,20-21H,15-16,18-19,22H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 85 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213393
(CHEMBL232548 | methyl 4-((2-(1-benzoyl-4-phenylpip...)Show SMILES COC(=O)c1ccc(Cn2ccnc2C2(CCN(CC2)C(=O)c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C30H29N3O3/c1-36-28(35)25-14-12-23(13-15-25)22-33-21-18-31-29(33)30(26-10-6-3-7-11-26)16-19-32(20-17-30)27(34)24-8-4-2-5-9-24/h2-15,18,21H,16-17,19-20,22H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 88 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213400
(CHEMBL391623 | ethyl 4-(1-(4-hydroxybenzyl)-1H-imi...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(O)cc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O3/c1-2-30-23(29)26-15-12-24(13-16-26,20-6-4-3-5-7-20)22-25-14-17-27(22)18-19-8-10-21(28)11-9-19/h3-11,14,17,28H,2,12-13,15-16,18H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 108 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213378
(CHEMBL233143 | cyclohexyl 4-(1-benzyl-1H-imidazol-...)Show SMILES O=C(OC1CCCCC1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H33N3O2/c32-27(33-25-14-8-3-9-15-25)30-19-16-28(17-20-30,24-12-6-2-7-13-24)26-29-18-21-31(26)22-23-10-4-1-5-11-23/h1-2,4-7,10-13,18,21,25H,3,8-9,14-17,19-20,22H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 121 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213394
(CHEMBL233368 | benzyl 4-(1-benzyl-1H-imidazol-2-yl...)Show SMILES O=C(OCc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H29N3O2/c33-28(34-23-25-12-6-2-7-13-25)31-19-16-29(17-20-31,26-14-8-3-9-15-26)27-30-18-21-32(27)22-24-10-4-1-5-11-24/h1-15,18,21H,16-17,19-20,22-23H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 121 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213404
((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...)Show SMILES O=C(N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H27N3O/c32-26(24-12-6-2-7-13-24)30-19-16-28(17-20-30,25-14-8-3-9-15-25)27-29-18-21-31(27)22-23-10-4-1-5-11-23/h1-15,18,21H,16-17,19-20,22H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 124 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213399
((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...)Show SMILES Cc1cc(C)c(C(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)c(C)c1 Show InChI InChI=1S/C31H33N3O/c1-23-20-24(2)28(25(3)21-23)29(35)33-17-14-31(15-18-33,27-12-8-5-9-13-27)30-32-16-19-34(30)22-26-10-6-4-7-11-26/h4-13,16,19-21H,14-15,17-18,22H2,1-3H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 125 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213402
(CHEMBL234807 | ethyl 4-(1-(cyclohexylmethyl)-1H-im...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1CC1CCCCC1)c1ccccc1 Show InChI InChI=1S/C24H33N3O2/c1-2-29-23(28)26-16-13-24(14-17-26,21-11-7-4-8-12-21)22-25-15-18-27(22)19-20-9-5-3-6-10-20/h4,7-8,11-12,15,18,20H,2-3,5-6,9-10,13-14,16-17,19H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 147 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213383
(4-((2-(1-benzoyl-4-phenylpiperidin-4-yl)-1H-imidaz...)Show SMILES CCN(CC)C(=O)c1ccc(Cn2ccnc2C2(CCN(CC2)C(=O)c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C33H36N4O2/c1-3-35(4-2)30(38)28-17-15-26(16-18-28)25-37-24-21-34-32(37)33(29-13-9-6-10-14-29)19-22-36(23-20-33)31(39)27-11-7-5-8-12-27/h5-18,21,24H,3-4,19-20,22-23,25H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213406
(CHEMBL232740 | ethyl 4-(1-benzyl-1H-imidazol-2-yl)...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O2/c1-2-29-23(28)26-16-13-24(14-17-26,21-11-7-4-8-12-21)22-25-15-18-27(22)19-20-9-5-3-6-10-20/h3-12,15,18H,2,13-14,16-17,19H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 171 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213401
(4-[1-(1-methyl-pyridin-2-yl)-1H-imidazol-2-yl]-4-p...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccccn1)c1ccccc1 Show InChI InChI=1S/C23H26N4O2/c1-2-29-22(28)26-15-11-23(12-16-26,19-8-4-3-5-9-19)21-25-14-17-27(21)18-20-10-6-7-13-24-20/h3-10,13-14,17H,2,11-12,15-16,18H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 173 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213398
(CHEMBL232937 | butyl 4-(1-benzyl-1H-imidazol-2-yl)...)Show SMILES CCCCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H31N3O2/c1-2-3-20-31-25(30)28-17-14-26(15-18-28,23-12-8-5-9-13-23)24-27-16-19-29(24)21-22-10-6-4-7-11-22/h4-13,16,19H,2-3,14-15,17-18,20-21H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 188 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213380
(CHEMBL400436 | isopropyl 4-(1-benzyl-1H-imidazol-2...)Show SMILES CC(C)OC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O2/c1-20(2)30-24(29)27-16-13-25(14-17-27,22-11-7-4-8-12-22)23-26-15-18-28(23)19-21-9-5-3-6-10-21/h3-12,15,18,20H,13-14,16-17,19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 201 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213395
(CHEMBL231781 | ethyl 4-(1-(4-methoxybenzyl)-1H-imi...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(OC)cc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O3/c1-3-31-24(29)27-16-13-25(14-17-27,21-7-5-4-6-8-21)23-26-15-18-28(23)19-20-9-11-22(30-2)12-10-20/h4-12,15,18H,3,13-14,16-17,19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 201 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213382
((E)-ethyl 4-(1-cinnamyl-1H-imidazol-2-yl)-4-phenyl...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1C\C=C\c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29N3O2/c1-2-31-25(30)29-19-15-26(16-20-29,23-13-7-4-8-14-23)24-27-17-21-28(24)18-9-12-22-10-5-3-6-11-22/h3-14,17,21H,2,15-16,18-20H2,1H3/b12-9+ | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 280 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213373
((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...)Show SMILES Cc1cc(C)cc(c1)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H31N3O/c1-23-19-24(2)21-26(20-23)28(34)32-16-13-30(14-17-32,27-11-7-4-8-12-27)29-31-15-18-33(29)22-25-9-5-3-6-10-25/h3-12,15,18-21H,13-14,16-17,22H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 284 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213374
(CHEMBL437397 | phenyl(4-phenyl-4-(1-(1-phenylethyl...)Show SMILES CC(c1ccccc1)n1ccnc1C1(CCN(CC1)C(=O)c1ccccc1)c1ccccc1 |w:1.0| Show InChI InChI=1S/C29H29N3O/c1-23(24-11-5-2-6-12-24)32-22-19-30-28(32)29(26-15-9-4-10-16-26)17-20-31(21-18-29)27(33)25-13-7-3-8-14-25/h2-16,19,22-23H,17-18,20-21H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 334 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213388
(CHEMBL233570 | ethyl 4-(1-(3-methoxybenzyl)-1H-imi...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1cccc(OC)c1)c1ccccc1 Show InChI InChI=1S/C25H29N3O3/c1-3-31-24(29)27-15-12-25(13-16-27,21-9-5-4-6-10-21)23-26-14-17-28(23)19-20-8-7-11-22(18-20)30-2/h4-11,14,17-18H,3,12-13,15-16,19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 366 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213403
(CHEMBL391852 | ethyl 4-phenyl-4-(1-(1-phenylethyl)...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1C(C)c1ccccc1)c1ccccc1 |w:16.18| Show InChI InChI=1S/C25H29N3O2/c1-3-30-24(29)27-17-14-25(15-18-27,22-12-8-5-9-13-22)23-26-16-19-28(23)20(2)21-10-6-4-7-11-21/h4-13,16,19-20H,3,14-15,17-18H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213391
((3,5-bis(trifluoromethyl)phenyl)(4-(1-benzyl-1H-im...)Show SMILES FC(F)(F)c1cc(cc(c1)C(F)(F)F)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H25F6N3O/c31-29(32,33)24-17-22(18-25(19-24)30(34,35)36)26(40)38-14-11-28(12-15-38,23-9-5-2-6-10-23)27-37-13-16-39(27)20-21-7-3-1-4-8-21/h1-10,13,16-19H,11-12,14-15,20H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213401
(4-[1-(1-methyl-pyridin-2-yl)-1H-imidazol-2-yl]-4-p...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccccn1)c1ccccc1 Show InChI InChI=1S/C23H26N4O2/c1-2-29-22(28)26-15-11-23(12-16-26,19-8-4-3-5-9-19)21-25-14-17-27(21)18-20-10-6-7-13-24-20/h3-10,13-14,17H,2,11-12,15-16,18H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213397
(CHEMBL231783 | ethyl 4-(1-(3-fluorobenzyl)-1H-imid...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1cccc(F)c1)c1ccccc1 Show InChI InChI=1S/C24H26FN3O2/c1-2-30-23(29)27-14-11-24(12-15-27,20-8-4-3-5-9-20)22-26-13-16-28(22)18-19-7-6-10-21(25)17-19/h3-10,13,16-17H,2,11-12,14-15,18H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213394
(CHEMBL233368 | benzyl 4-(1-benzyl-1H-imidazol-2-yl...)Show SMILES O=C(OCc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H29N3O2/c33-28(34-23-25-12-6-2-7-13-25)31-19-16-29(17-20-31,26-14-8-3-9-15-26)27-30-18-21-32(27)22-24-10-4-1-5-11-24/h1-15,18,21H,16-17,19-20,22-23H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213384
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show SMILES O=C(Cc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H29N3O/c33-27(22-24-10-4-1-5-11-24)31-19-16-29(17-20-31,26-14-8-3-9-15-26)28-30-18-21-32(28)23-25-12-6-2-7-13-25/h1-15,18,21H,16-17,19-20,22-23H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213390
(CHEMBL392266 | tert-butyl 4-(1-benzyl-1H-imidazol-...)Show SMILES CC(C)(C)OC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H31N3O2/c1-25(2,3)31-24(30)28-17-14-26(15-18-28,22-12-8-5-9-13-22)23-27-16-19-29(23)20-21-10-6-4-7-11-21/h4-13,16,19H,14-15,17-18,20H2,1-3H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213405
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show SMILES CCC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O/c1-2-22(28)26-16-13-24(14-17-26,21-11-7-4-8-12-21)23-25-15-18-27(23)19-20-9-5-3-6-10-20/h3-12,15,18H,2,13-14,16-17,19H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213387
(CHEMBL393965 | ethyl 4-(1-(4-(methoxycarbonyl)benz...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(cc1)C(=O)OC)c1ccccc1 Show InChI InChI=1S/C26H29N3O4/c1-3-33-25(31)28-16-13-26(14-17-28,22-7-5-4-6-8-22)24-27-15-18-29(24)19-20-9-11-21(12-10-20)23(30)32-2/h4-12,15,18H,3,13-14,16-17,19H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213396
(CHEMBL232345 | methyl 3-((2-(1-benzoyl-4-phenylpip...)Show SMILES COC(=O)c1cccc(Cn2ccnc2C2(CCN(CC2)C(=O)c2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C30H29N3O3/c1-36-28(35)25-12-8-9-23(21-25)22-33-20-17-31-29(33)30(26-13-6-3-7-14-26)15-18-32(19-16-30)27(34)24-10-4-2-5-11-24/h2-14,17,20-21H,15-16,18-19,22H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213378
(CHEMBL233143 | cyclohexyl 4-(1-benzyl-1H-imidazol-...)Show SMILES O=C(OC1CCCCC1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H33N3O2/c32-27(33-25-14-8-3-9-15-25)30-19-16-28(17-20-30,24-12-6-2-7-13-24)26-29-18-21-31(26)22-23-10-4-1-5-11-23/h1-2,4-7,10-13,18,21,25H,3,8-9,14-17,19-20,22H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213398
(CHEMBL232937 | butyl 4-(1-benzyl-1H-imidazol-2-yl)...)Show SMILES CCCCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H31N3O2/c1-2-3-20-31-25(30)28-17-14-26(15-18-28,23-12-8-5-9-13-23)24-27-16-19-29(24)21-22-10-6-4-7-11-22/h4-13,16,19H,2-3,14-15,17-18,20-21H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213375
(CHEMBL234389 | ethyl 4-(1-(1-methylnaphthalen-2-yl...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1-c1ccc2ccccc2c1C)c1ccccc1 Show InChI InChI=1S/C28H29N3O2/c1-3-33-27(32)30-18-15-28(16-19-30,23-10-5-4-6-11-23)26-29-17-20-31(26)25-14-13-22-9-7-8-12-24(22)21(25)2/h4-14,17,20H,3,15-16,18-19H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213372
(CHEMBL399205 | propyl 4-(1-benzyl-1H-imidazol-2-yl...)Show SMILES CCCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O2/c1-2-19-30-24(29)27-16-13-25(14-17-27,22-11-7-4-8-12-22)23-26-15-18-28(23)20-21-9-5-3-6-10-21/h3-12,15,18H,2,13-14,16-17,19-20H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213392
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show SMILES CC(C)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O/c1-20(2)23(29)27-16-13-25(14-17-27,22-11-7-4-8-12-22)24-26-15-18-28(24)19-21-9-5-3-6-10-21/h3-12,15,18,20H,13-14,16-17,19H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213385
(CHEMBL233427 | ethyl 4-(1-(4-fluorobenzyl)-1H-imid...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(F)cc1)c1ccccc1 Show InChI InChI=1S/C24H26FN3O2/c1-2-30-23(29)27-15-12-24(13-16-27,20-6-4-3-5-7-20)22-26-14-17-28(22)18-19-8-10-21(25)11-9-19/h3-11,14,17H,2,12-13,15-16,18H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213382
((E)-ethyl 4-(1-cinnamyl-1H-imidazol-2-yl)-4-phenyl...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1C\C=C\c1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H29N3O2/c1-2-31-25(30)29-19-15-26(16-20-29,23-13-7-4-8-14-23)24-27-17-21-28(24)18-9-12-22-10-5-3-6-11-22/h3-14,17,21H,2,15-16,18-20H2,1H3/b12-9+ | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213389
((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...)Show SMILES O=C(C1CC1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H27N3O/c29-23(21-11-12-21)27-16-13-25(14-17-27,22-9-5-2-6-10-22)24-26-15-18-28(24)19-20-7-3-1-4-8-20/h1-10,15,18,21H,11-14,16-17,19H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213402
(CHEMBL234807 | ethyl 4-(1-(cyclohexylmethyl)-1H-im...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1CC1CCCCC1)c1ccccc1 Show InChI InChI=1S/C24H33N3O2/c1-2-29-23(28)26-16-13-24(14-17-26,21-11-7-4-8-12-21)22-25-15-18-27(22)19-20-9-5-3-6-10-20/h4,7-8,11-12,15,18,20H,2-3,5-6,9-10,13-14,16-17,19H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213380
(CHEMBL400436 | isopropyl 4-(1-benzyl-1H-imidazol-2...)Show SMILES CC(C)OC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O2/c1-20(2)30-24(29)27-16-13-25(14-17-27,22-11-7-4-8-12-22)23-26-15-18-28(23)19-21-9-5-3-6-10-21/h3-12,15,18,20H,13-14,16-17,19H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213373
((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...)Show SMILES Cc1cc(C)cc(c1)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C30H31N3O/c1-23-19-24(2)21-26(20-23)28(34)32-16-13-30(14-17-32,27-11-7-4-8-12-27)29-31-15-18-33(29)22-25-9-5-3-6-10-25/h3-12,15,18-21H,13-14,16-17,22H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213400
(CHEMBL391623 | ethyl 4-(1-(4-hydroxybenzyl)-1H-imi...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(O)cc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O3/c1-2-30-23(29)26-15-12-24(13-16-26,20-6-4-3-5-7-20)22-25-14-17-27(22)18-19-8-10-21(28)11-9-19/h3-11,14,17,28H,2,12-13,15-16,18H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213379
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show InChI InChI=1S/C23H25N3O/c1-19(27)25-15-12-23(13-16-25,21-10-6-3-7-11-21)22-24-14-17-26(22)18-20-8-4-2-5-9-20/h2-11,14,17H,12-13,15-16,18H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213386
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show SMILES COCC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O2/c1-29-19-22(28)26-15-12-24(13-16-26,21-10-6-3-7-11-21)23-25-14-17-27(23)18-20-8-4-2-5-9-20/h2-11,14,17H,12-13,15-16,18-19H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >465 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213392
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show SMILES CC(C)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O/c1-20(2)23(29)27-16-13-25(14-17-27,22-11-7-4-8-12-22)24-26-15-18-28(24)19-21-9-5-3-6-10-21/h3-12,15,18,20H,13-14,16-17,19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 621 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213386
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show SMILES COCC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O2/c1-29-19-22(28)26-15-12-24(13-16-26,21-10-6-3-7-11-21)23-25-14-17-27(23)18-20-8-4-2-5-9-20/h2-11,14,17H,12-13,15-16,18-19H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 622 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50213375
(CHEMBL234389 | ethyl 4-(1-(1-methylnaphthalen-2-yl...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1-c1ccc2ccccc2c1C)c1ccccc1 Show InChI InChI=1S/C28H29N3O2/c1-3-33-27(32)30-18-15-28(16-19-30,23-10-5-4-6-11-23)26-29-17-20-31(26)25-14-13-22-9-7-8-12-24(22)21(25)2/h4-14,17,20H,3,15-16,18-19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 642 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DPDPE from cloned human delta opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213379
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show InChI InChI=1S/C23H25N3O/c1-19(27)25-15-12-23(13-16-25,21-10-6-3-7-11-21)22-24-14-17-26(22)18-20-8-4-2-5-9-20/h2-11,14,17H,12-13,15-16,18H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213406
(CHEMBL232740 | ethyl 4-(1-benzyl-1H-imidazol-2-yl)...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H27N3O2/c1-2-29-23(28)26-16-13-24(14-17-26,21-11-7-4-8-12-21)22-25-15-18-27(22)19-20-9-5-3-6-10-20/h3-12,15,18H,2,13-14,16-17,19H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| 2.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213375
(CHEMBL234389 | ethyl 4-(1-(1-methylnaphthalen-2-yl...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1-c1ccc2ccccc2c1C)c1ccccc1 Show InChI InChI=1S/C28H29N3O2/c1-3-33-27(32)30-18-15-28(16-19-30,23-10-5-4-6-11-23)26-29-17-20-31(26)25-14-13-22-9-7-8-12-24(22)21(25)2/h4-14,17,20H,3,15-16,18-19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 3.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213407
(1-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...)Show SMILES CC(C)(C)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C26H31N3O/c1-25(2,3)24(30)28-17-14-26(15-18-28,22-12-8-5-9-13-22)23-27-16-19-29(23)20-21-10-6-4-7-11-21/h4-13,16,19H,14-15,17-18,20H2,1-3H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213381
(CHEMBL232137 | methyl 4-((2-(1-(2-methoxyacetyl)-4...)Show SMILES COCC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(cc1)C(=O)OC)c1ccccc1 Show InChI InChI=1S/C26H29N3O4/c1-32-19-23(30)28-15-12-26(13-16-28,22-6-4-3-5-7-22)25-27-14-17-29(25)18-20-8-10-21(11-9-20)24(31)33-2/h3-11,14,17H,12-13,15-16,18-19H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213383
(4-((2-(1-benzoyl-4-phenylpiperidin-4-yl)-1H-imidaz...)Show SMILES CCN(CC)C(=O)c1ccc(Cn2ccnc2C2(CCN(CC2)C(=O)c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C33H36N4O2/c1-3-35(4-2)30(38)28-17-15-26(16-18-28)25-37-24-21-34-32(37)33(29-13-9-6-10-14-29)19-22-36(23-20-33)31(39)27-11-7-5-8-12-27/h5-18,21,24H,3-4,19-20,22-23,25H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213393
(CHEMBL232548 | methyl 4-((2-(1-benzoyl-4-phenylpip...)Show SMILES COC(=O)c1ccc(Cn2ccnc2C2(CCN(CC2)C(=O)c2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C30H29N3O3/c1-36-28(35)25-14-12-23(13-15-25)22-33-21-18-31-29(33)30(26-10-6-3-7-11-26)16-19-32(20-17-30)27(34)24-8-4-2-5-9-24/h2-15,18,21H,16-17,19-20,22H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213399
((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...)Show SMILES Cc1cc(C)c(C(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)c(C)c1 Show InChI InChI=1S/C31H33N3O/c1-23-20-24(2)28(25(3)21-23)29(35)33-17-14-31(15-18-33,27-12-8-5-9-13-27)30-32-16-19-34(30)22-26-10-6-4-7-11-26/h4-13,16,19-21H,14-15,17-18,22H2,1-3H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213376
(2-methoxy-1-(4-phenyl-4-(1-(1-phenylethyl)-1H-imid...)Show SMILES COCC(=O)N1CCC(CC1)(c1nccn1C(C)c1ccccc1)c1ccccc1 |w:16.18| Show InChI InChI=1S/C25H29N3O2/c1-20(21-9-5-3-6-10-21)28-18-15-26-24(28)25(22-11-7-4-8-12-22)13-16-27(17-14-25)23(29)19-30-2/h3-12,15,18,20H,13-14,16-17,19H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213372
(CHEMBL399205 | propyl 4-(1-benzyl-1H-imidazol-2-yl...)Show SMILES CCCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O2/c1-2-19-30-24(29)27-16-13-25(14-17-27,22-11-7-4-8-12-22)23-26-15-18-28(23)20-21-9-5-3-6-10-21/h3-12,15,18H,2,13-14,16-17,19-20H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213377
(CHEMBL232738 | methyl 4-(1-benzyl-1H-imidazol-2-yl...)Show SMILES COC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H25N3O2/c1-28-22(27)25-15-12-23(13-16-25,20-10-6-3-7-11-20)21-24-14-17-26(21)18-19-8-4-2-5-9-19/h2-11,14,17H,12-13,15-16,18H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213374
(CHEMBL437397 | phenyl(4-phenyl-4-(1-(1-phenylethyl...)Show SMILES CC(c1ccccc1)n1ccnc1C1(CCN(CC1)C(=O)c1ccccc1)c1ccccc1 |w:1.0| Show InChI InChI=1S/C29H29N3O/c1-23(24-11-5-2-6-12-24)32-22-19-30-28(32)29(26-15-9-4-10-16-26)17-20-31(21-18-29)27(33)25-13-7-3-8-14-25/h2-16,19,22-23H,17-18,20-21H2,1H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213404
((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...)Show SMILES O=C(N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H27N3O/c32-26(24-12-6-2-7-13-24)30-19-16-28(17-20-30,25-14-8-3-9-15-25)27-29-18-21-31(27)22-23-10-4-1-5-11-23/h1-15,18,21H,16-17,19-20,22H2 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213376
(2-methoxy-1-(4-phenyl-4-(1-(1-phenylethyl)-1H-imid...)Show SMILES COCC(=O)N1CCC(CC1)(c1nccn1C(C)c1ccccc1)c1ccccc1 |w:16.18| Show InChI InChI=1S/C25H29N3O2/c1-20(21-9-5-3-6-10-21)28-18-15-26-24(28)25(22-11-7-4-8-12-22)13-16-27(17-14-25)23(29)19-30-2/h3-12,15,18,20H,13-14,16-17,19H2,1-2H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213388
(CHEMBL233570 | ethyl 4-(1-(3-methoxybenzyl)-1H-imi...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1cccc(OC)c1)c1ccccc1 Show InChI InChI=1S/C25H29N3O3/c1-3-31-24(29)27-15-12-25(13-16-27,21-9-5-4-6-10-21)23-26-14-17-28(23)19-20-8-7-11-22(18-20)30-2/h4-11,14,17-18H,3,12-13,15-16,19H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Homo sapiens (Human)) | BDBM50213397
(CHEMBL231783 | ethyl 4-(1-(3-fluorobenzyl)-1H-imid...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1cccc(F)c1)c1ccccc1 Show InChI InChI=1S/C24H26FN3O2/c1-2-30-23(29)27-14-11-24(12-15-27,20-8-4-3-5-9-20)22-26-13-16-28(22)18-19-7-6-10-21(25)17-19/h3-10,13,16-17H,2,11-12,14-15,18H2,1H3 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69593 from cloned human kappa opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(Homo sapiens (Human)) | BDBM50213395
(CHEMBL231781 | ethyl 4-(1-(4-methoxybenzyl)-1H-imi...)Show SMILES CCOC(=O)N1CCC(CC1)(c1nccn1Cc1ccc(OC)cc1)c1ccccc1 Show InChI InChI=1S/C25H29N3O3/c1-3-31-24(29)27-16-13-25(14-17-27,21-7-5-4-6-8-21)23-26-15-18-28(23)19-20-9-11-22(30-2)12-10-20/h4-12,15,18H,3,13-14,16-17,19H2,1-2H3 | PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| >4.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Johnson & Johnson Pharmaceutical Research & Development
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from cloned human mu opioid receptor |
Bioorg Med Chem Lett 17: 3860-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.05.012
BindingDB Entry DOI: 10.7270/Q2TT4QMM |
More data for this
Ligand-Target Pair | |
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