Found 4 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Macrophage metalloelastase
(Homo sapiens (Human)) | BDBM50216172
((Dichloro-phosphono-methyl)-phosphonic acid | CHEM...)Show InChI InChI=1S/CH4Cl2O6P2/c2-1(3,10(4,5)6)11(7,8)9/h(H2,4,5,6)(H2,7,8,9) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 1.21E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Bari
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP12 after 1 hr |
J Med Chem 50: 3434-41 (2007)
Article DOI: 10.1021/jm061435l
BindingDB Entry DOI: 10.7270/Q2G44Q0J |
More data for this
Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50216172
((Dichloro-phosphono-methyl)-phosphonic acid | CHEM...)Show InChI InChI=1S/CH4Cl2O6P2/c2-1(3,10(4,5)6)11(7,8)9/h(H2,4,5,6)(H2,7,8,9) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 1.45E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Bari
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP2 after 1 hr |
J Med Chem 50: 3434-41 (2007)
Article DOI: 10.1021/jm061435l
BindingDB Entry DOI: 10.7270/Q2G44Q0J |
More data for this
Ligand-Target Pair | |
Stromelysin-1
(Homo sapiens (Human)) | BDBM50216172
((Dichloro-phosphono-methyl)-phosphonic acid | CHEM...)Show InChI InChI=1S/CH4Cl2O6P2/c2-1(3,10(4,5)6)11(7,8)9/h(H2,4,5,6)(H2,7,8,9) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 3.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Bari
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP3 after 1 hr |
J Med Chem 50: 3434-41 (2007)
Article DOI: 10.1021/jm061435l
BindingDB Entry DOI: 10.7270/Q2G44Q0J |
More data for this
Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50216172
((Dichloro-phosphono-methyl)-phosphonic acid | CHEM...)Show InChI InChI=1S/CH4Cl2O6P2/c2-1(3,10(4,5)6)11(7,8)9/h(H2,4,5,6)(H2,7,8,9) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 3.20E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università di Bari
Curated by ChEMBL
| Assay Description
Inhibition of human recombinant MMP9 after 1 hr |
J Med Chem 50: 3434-41 (2007)
Article DOI: 10.1021/jm061435l
BindingDB Entry DOI: 10.7270/Q2G44Q0J |
More data for this
Ligand-Target Pair | |
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