Affinity Data by PubMed id=17632515

PubMed code 17632515

Found 13 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Myosin light chain kinase, smooth muscle (Homo sapiens (Human))	BDBM50326009 (5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...) Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of MYLK				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326009 (5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...) Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein interaction with TMR-labeled A/U-rich element of TNFalpha by confocal fluctuation ...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326010 (CHEMBL1242196 \| Dehydromutactin) Show SMILES Cc1cc(O)c2c(O)cccc2c1-c1cc(O)cc(=O)o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Binding affinity to recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of COX2 by confocal fluctuation sp...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326010 (CHEMBL1242196 \| Dehydromutactin) Show SMILES Cc1cc(O)c2c(O)cccc2c1-c1cc(O)cc(=O)o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.0100	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of COX2 by confocal fluctuation spectros...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326009 (5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...) Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein dimerization with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spe...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326010 (CHEMBL1242196 \| Dehydromutactin) Show SMILES Cc1cc(O)c2c(O)cccc2c1-c1cc(O)cc(=O)o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spectros...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326009 (5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...) Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein interaction with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spec...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326010 (CHEMBL1242196 \| Dehydromutactin) Show SMILES Cc1cc(O)c2c(O)cccc2c1-c1cc(O)cc(=O)o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant full length HuR assessed as protein interaction with TMR-labeled A/U-rich element of COX2 by confocal fluctuation spectrosc...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326009 (5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...) Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Binding affinity recombinant HuR RRM1/RRM2 domain by confocal fluctuation spectroscopy				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326009 (5,8-dihydroxy-3-methylnaphtho[2,3-c]furan-4(9H)-on...) Show SMILES Cc1occ2Cc3c(O)ccc(O)c3C(=O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant HuR RRM1/RRM2 domain assessed as protein dimerization with TMR-labeled A/U-rich element of TNFalpha by confocal fluctuation...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326011 (CHEMBL1240971 \| Okicenone) Show SMILES Cc1cc(O)cc2cc3C(O)CCC(=O)c3c(O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Binding affinity to HuR after 24 hrs by microdialysis method				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326011 (CHEMBL1240971 \| Okicenone) Show SMILES Cc1cc(O)cc2cc3C(O)CCC(=O)c3c(O)c12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Binding affinity to recombinant full length HuR assessed as protein dimerization with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation sp...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair
ELAV-like protein 1 (Homo sapiens (Human))	BDBM50326010 (CHEMBL1242196 \| Dehydromutactin) Show SMILES Cc1cc(O)c2c(O)cccc2c1-c1cc(O)cc(=O)o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant full length HuR assessed as protein interaction with TMR-labeled A/U-rich element of IL-2 by confocal fluctuation spectrosc...				Nat Chem Biol 3: 508-15 (2007) Article DOI: 10.1038/nchembio.2007.14 BindingDB Entry DOI: 10.7270/Q2QN670V
					More data for this Ligand-Target Pair

* indicates data uncertainty>20%