Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM35053 (K00486) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University Hospital Basel | Assay Description Phosphorylation reactions were monitored using a coupled-enzyme assay in which ADP production was coupled to NADH oxidation by pyruvate kinase and la... | Cancer Res 67: 6916-24 (2007) Article DOI: 10.1158/0008-5472.CAN-07-0320 BindingDB Entry DOI: 10.7270/Q23X850Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM35052 (K00152 | US10047093, 8-39 | US10392392, Example 8-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University Hospital Basel | Assay Description Phosphorylation reactions were monitored using a coupled-enzyme assay in which ADP production was coupled to NADH oxidation by pyruvate kinase and la... | Cancer Res 67: 6916-24 (2007) Article DOI: 10.1158/0008-5472.CAN-07-0320 BindingDB Entry DOI: 10.7270/Q23X850Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM11835 (1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-a]py...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University Hospital Basel | Assay Description Phosphorylation reactions were monitored using a coupled-enzyme assay in which ADP production was coupled to NADH oxidation by pyruvate kinase and la... | Cancer Res 67: 6916-24 (2007) Article DOI: 10.1158/0008-5472.CAN-07-0320 BindingDB Entry DOI: 10.7270/Q23X850Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human)) | BDBM11835 (1-(3-{6-[(cyclopropylmethyl)amino]imidazo[1,2-a]py...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University Hospital Basel | Assay Description Phosphorylation reactions were monitored using a coupled-enzyme assay in which ADP production was coupled to NADH oxidation by pyruvate kinase and la... | Cancer Res 67: 6916-24 (2007) Article DOI: 10.1158/0008-5472.CAN-07-0320 BindingDB Entry DOI: 10.7270/Q23X850Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human)) | BDBM35053 (K00486) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University Hospital Basel | Assay Description Phosphorylation reactions were monitored using a coupled-enzyme assay in which ADP production was coupled to NADH oxidation by pyruvate kinase and la... | Cancer Res 67: 6916-24 (2007) Article DOI: 10.1158/0008-5472.CAN-07-0320 BindingDB Entry DOI: 10.7270/Q23X850Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human)) | BDBM35052 (K00152 | US10047093, 8-39 | US10392392, Example 8-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.10E+3 | n/a | n/a | n/a | n/a | 7.5 | 25 |
University Hospital Basel | Assay Description Phosphorylation reactions were monitored using a coupled-enzyme assay in which ADP production was coupled to NADH oxidation by pyruvate kinase and la... | Cancer Res 67: 6916-24 (2007) Article DOI: 10.1158/0008-5472.CAN-07-0320 BindingDB Entry DOI: 10.7270/Q23X850Z | |||||||||||
More data for this Ligand-Target Pair |