Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50008679 (4-[2-(9-Aminomethyl-6,10-dioxo-octahydro-pyridazin...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Concentration required to inhibit HIV-1 protease activity calculated from plots of % inhibition vs inhibitor concentration | J Med Chem 34: 3395-9 (1992) BindingDB Entry DOI: 10.7270/Q2Z3208P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50008681 (4-{2-[9-(Benzylamino-methyl)-6,10-dioxo-1,4,7,8,9,...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Concentration required to inhibit HIV-1 protease activity calculated from plots of % inhibition vs inhibitor concentration | J Med Chem 34: 3395-9 (1992) BindingDB Entry DOI: 10.7270/Q2Z3208P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50368162 (CHEMBL1790846) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Concentration required to inhibit HIV-1 protease activity calculated from plots of % inhibition vs inhibitor concentration | J Med Chem 34: 3395-9 (1992) BindingDB Entry DOI: 10.7270/Q2Z3208P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50008680 (2-[2-(4-{2-[9-(Benzylamino-methyl)-6,10-dioxo-1,4,...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Concentration required to inhibit HIV-1 protease activity calculated from plots of % inhibition vs inhibitor concentration | J Med Chem 34: 3395-9 (1992) BindingDB Entry DOI: 10.7270/Q2Z3208P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gag-Pol polyprotein [489-587] (Human immunodeficiency virus type 1) | BDBM50368161 (CHEMBL1790845) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.60E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Illinois Curated by ChEMBL | Assay Description Concentration required to inhibit HIV-1 protease activity calculated from plots of % inhibition vs inhibitor concentration | J Med Chem 34: 3395-9 (1992) BindingDB Entry DOI: 10.7270/Q2Z3208P | |||||||||||
More data for this Ligand-Target Pair |