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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Protein kinase YpkA (Yersinia pestis) | BDBM22042 ((3Z)-5-bromo-3-[3-(3-chlorophenyl)-4-oxo-2-thioxo-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet  | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.81E+3 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Rockefeller University | Assay Description Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding... | J Med Chem 50: 3980-3 (2007) Article DOI: 10.1021/jm070645a BindingDB Entry DOI: 10.7270/Q2ZW1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Homo sapiens (Human)) | BDBM22042 ((3Z)-5-bromo-3-[3-(3-chlorophenyl)-4-oxo-2-thioxo-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.45E+3 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Rockefeller University | Assay Description Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding... | J Med Chem 50: 3980-3 (2007) Article DOI: 10.1021/jm070645a BindingDB Entry DOI: 10.7270/Q2ZW1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein kinase YpkA (Yersinia pestis) | BDBM22045 (5-({4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}met...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.87E+3 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Rockefeller University | Assay Description Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding... | J Med Chem 50: 3980-3 (2007) Article DOI: 10.1021/jm070645a BindingDB Entry DOI: 10.7270/Q2ZW1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein kinase YpkA (Yersinia pestis) | BDBM22044 ((5Z)-5-{[5-(2-chloro-5-nitrophenyl)furan-2-yl]meth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.72E+3 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Rockefeller University | Assay Description Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding... | J Med Chem 50: 3980-3 (2007) Article DOI: 10.1021/jm070645a BindingDB Entry DOI: 10.7270/Q2ZW1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein kinase YpkA (Yersinia pestis) | BDBM22043 (N-(3-nitrophenyl)-9,10-dioxo-9,10-dihydroanthracen...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.98E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Rockefeller University | Assay Description Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding... | J Med Chem 50: 3980-3 (2007) Article DOI: 10.1021/jm070645a BindingDB Entry DOI: 10.7270/Q2ZW1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Homo sapiens (Human)) | BDBM22045 (5-({4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}met...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.30E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Rockefeller University | Assay Description Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding... | J Med Chem 50: 3980-3 (2007) Article DOI: 10.1021/jm070645a BindingDB Entry DOI: 10.7270/Q2ZW1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Homo sapiens (Human)) | BDBM22044 ((5Z)-5-{[5-(2-chloro-5-nitrophenyl)furan-2-yl]meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.45E+4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Rockefeller University | Assay Description Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding... | J Med Chem 50: 3980-3 (2007) Article DOI: 10.1021/jm070645a BindingDB Entry DOI: 10.7270/Q2ZW1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein kinase C alpha type (Homo sapiens (Human)) | BDBM22043 (N-(3-nitrophenyl)-9,10-dioxo-9,10-dihydroanthracen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.65E+5 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Rockefeller University | Assay Description Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding... | J Med Chem 50: 3980-3 (2007) Article DOI: 10.1021/jm070645a BindingDB Entry DOI: 10.7270/Q2ZW1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Mitogen-activated protein kinase 1 (Homo sapiens (Human)) | BDBM22043 (N-(3-nitrophenyl)-9,10-dioxo-9,10-dihydroanthracen...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Rockefeller University | Assay Description Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding... | J Med Chem 50: 3980-3 (2007) Article DOI: 10.1021/jm070645a BindingDB Entry DOI: 10.7270/Q2ZW1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein kinase C alpha type (Homo sapiens (Human)) | BDBM22042 ((3Z)-5-bromo-3-[3-(3-chlorophenyl)-4-oxo-2-thioxo-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Rockefeller University | Assay Description Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding... | J Med Chem 50: 3980-3 (2007) Article DOI: 10.1021/jm070645a BindingDB Entry DOI: 10.7270/Q2ZW1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein kinase C alpha type (Homo sapiens (Human)) | BDBM22045 (5-({4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}met...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Rockefeller University | Assay Description Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding... | J Med Chem 50: 3980-3 (2007) Article DOI: 10.1021/jm070645a BindingDB Entry DOI: 10.7270/Q2ZW1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Protein kinase C alpha type (Homo sapiens (Human)) | BDBM22044 ((5Z)-5-{[5-(2-chloro-5-nitrophenyl)furan-2-yl]meth...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.05E+5 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Rockefeller University | Assay Description Kinase activity was assayed for autophosphorylation and phosphorylation of MBP with radio-labeled gamma-32P. IC50 values were calculated from binding... | J Med Chem 50: 3980-3 (2007) Article DOI: 10.1021/jm070645a BindingDB Entry DOI: 10.7270/Q2ZW1J6Z | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
