Affinity Data by PubMed id=17722902

PubMed code 17722902

Found 16 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50220011 (CHEMBL243925 \| L-(+)-2-amino-4-thiophosphonobutyri...) Show SMILES N[C@@H](CCP(O)(O)=S)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50174527 ((S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric...) Show SMILES CP(O)(=O)CC[C@H](N)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.12E+5	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50174527 ((S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric...) Show SMILES CP(O)(=O)CC[C@H](N)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50174527 ((S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric...) Show SMILES CP(O)(=O)CC[C@H](N)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.10E+6	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50220011 (CHEMBL243925 \| L-(+)-2-amino-4-thiophosphonobutyri...) Show SMILES N[C@@H](CCP(O)(O)=S)C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	730	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50220011 (CHEMBL243925 \| L-(+)-2-amino-4-thiophosphonobutyri...) Show SMILES N[C@@H](CCP(O)(O)=S)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.97E+5	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50220009 (CHEMBL241972 \| L-(+)-2-amino-4-[(hydroxy)phosphiny...) Show SMILES N[C@@H](CCP(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.40E+5	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR7 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50220011 (CHEMBL243925 \| L-(+)-2-amino-4-thiophosphonobutyri...) Show SMILES N[C@@H](CCP(O)(O)=S)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50220009 (CHEMBL241972 \| L-(+)-2-amino-4-[(hydroxy)phosphiny...) Show SMILES N[C@@H](CCP(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.72E+3	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 8 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	128	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR8 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50007548 ((S)-2-Amino-4-phosphono-butyric acid \| (S)-2-amino...) Show SMILES N[C@@H](CCP(O)(O)=O)C(O)=O \|r\| Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.08E+3	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50174527 ((S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric...) Show SMILES CP(O)(=O)CC[C@H](N)C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 6 (Rattus norvegicus (Rat))	BDBM50220009 (CHEMBL241972 \| L-(+)-2-amino-4-[(hydroxy)phosphiny...) Show SMILES N[C@@H](CCP(O)=O)C(O)=O Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.78E+4	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR6 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (Rattus norvegicus (Rat))	BDBM50220009 (CHEMBL241972 \| L-(+)-2-amino-4-[(hydroxy)phosphiny...) Show SMILES N[C@@H](CCP(O)=O)C(O)=O Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.05E+3	n/a	n/a	n/a	n/a
Université Paris Descartes Curated by ChEMBL					Assay Description Agonist activity at rat mGluR4 receptor expressed HEK293 cells assessed as effect on inositol phosphate production				J Med Chem 50: 4656-64 (2007) Article DOI: 10.1021/jm070400y BindingDB Entry DOI: 10.7270/Q2XP74NQ
Université Paris Descartes Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%