Found 24 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50183248
(2-{4-[4-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1ccc(cc1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(33-27-7-3-1-5-23(25)27)21-13-9-19(10-14-21)20-11-15-22(16-12-20)30-18-26(32)24-6-2-4-8-28(24)34-30/h1-18H | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned cPLA2 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50183244
(3-(4-(4-oxo-4H-chromen-2-yl)phenyl)-2-phenyl-4H-ch...)Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-24-18-27(33-25-12-6-4-10-22(24)25)19-14-16-20(17-15-19)28-29(32)23-11-5-7-13-26(23)34-30(28)21-8-2-1-3-9-21/h1-18H | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 8.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned cPLA2 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50183245
(6-[4-(4-Oxo-4H-chromen-2-yl)-phenyl]-2-phenyl-chro...)Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1ccc2oc(cc(=O)c2c1)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-25-17-30(33-27-9-5-4-8-23(25)27)21-12-10-19(11-13-21)22-14-15-28-24(16-22)26(32)18-29(34-28)20-6-2-1-3-7-20/h1-18H | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.19E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned cPLA2 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50183246
(6-[3-(4-Oxo-4H-chromen-2-yl)-phenyl]-2-phenyl-chro...)Show SMILES O=c1cc(oc2ccccc12)-c1cccc(c1)-c1ccc2oc(cc(=O)c2c1)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-25-17-30(33-27-12-5-4-11-23(25)27)22-10-6-9-20(15-22)21-13-14-28-24(16-21)26(32)18-29(34-28)19-7-2-1-3-8-19/h1-18H | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.68E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned cPLA2 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Group 10 secretory phospholipase A2
(Homo sapiens (Human)) | BDBM50183246
(6-[3-(4-Oxo-4H-chromen-2-yl)-phenyl]-2-phenyl-chro...)Show SMILES O=c1cc(oc2ccccc12)-c1cccc(c1)-c1ccc2oc(cc(=O)c2c1)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-25-17-30(33-27-12-5-4-11-23(25)27)22-10-6-9-20(15-22)21-13-14-28-24(16-21)26(32)18-29(34-28)19-7-2-1-3-8-19/h1-18H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.76E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned sPLA2-10 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50183247
(2-{4-[3-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1cccc(c1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(33-27-10-3-1-8-23(25)27)20-14-12-19(13-15-20)21-6-5-7-22(16-21)30-18-26(32)24-9-2-4-11-28(24)34-30/h1-18H | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.87E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned cPLA2 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50183249
(2,2'-Diphenyl-[6,6']bichromenyl-4,4'-dione | CHEMB...)Show SMILES O=c1cc(oc2ccc(cc12)-c1ccc2oc(cc(=O)c2c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(19-7-3-1-4-8-19)33-27-13-11-21(15-23(25)27)22-12-14-28-24(16-22)26(32)18-30(34-28)20-9-5-2-6-10-20/h1-18H | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.81E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned cPLA2 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Phospholipase A2
(Rattus norvegicus) | BDBM50183249
(2,2'-Diphenyl-[6,6']bichromenyl-4,4'-dione | CHEMB...)Show SMILES O=c1cc(oc2ccc(cc12)-c1ccc2oc(cc(=O)c2c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(19-7-3-1-4-8-19)33-27-13-11-21(15-23(25)27)22-12-14-28-24(16-22)26(32)18-30(34-28)20-9-5-2-6-10-20/h1-18H | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of rat cloned sPLA2-1B expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Phospholipase A2
(Rattus norvegicus) | BDBM50183245
(6-[4-(4-Oxo-4H-chromen-2-yl)-phenyl]-2-phenyl-chro...)Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1ccc2oc(cc(=O)c2c1)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-25-17-30(33-27-9-5-4-8-23(25)27)21-12-10-19(11-13-21)22-14-15-28-24(16-22)26(32)18-29(34-28)20-6-2-1-3-7-20/h1-18H | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of rat cloned sPLA2-1B expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Group 10 secretory phospholipase A2
(Homo sapiens (Human)) | BDBM50183248
(2-{4-[4-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1ccc(cc1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(33-27-7-3-1-5-23(25)27)21-13-9-19(10-14-21)20-11-15-22(16-12-20)30-18-26(32)24-6-2-4-8-28(24)34-30/h1-18H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned sPLA2-10 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Phospholipase A2
(Rattus norvegicus) | BDBM50183246
(6-[3-(4-Oxo-4H-chromen-2-yl)-phenyl]-2-phenyl-chro...)Show SMILES O=c1cc(oc2ccccc12)-c1cccc(c1)-c1ccc2oc(cc(=O)c2c1)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-25-17-30(33-27-12-5-4-11-23(25)27)22-10-6-9-20(15-22)21-13-14-28-24(16-21)26(32)18-29(34-28)19-7-2-1-3-8-19/h1-18H | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of rat cloned sPLA2-1B expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Phospholipase A2
(Rattus norvegicus) | BDBM50129952
(2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-c...)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1 |(13.25,-26.01,;14.59,-25.24,;14.59,-23.7,;15.92,-22.93,;17.26,-23.7,;17.26,-25.24,;15.93,-26.01,;18.58,-22.93,;19.91,-23.69,;21.23,-22.92,;22.57,-23.69,;21.22,-21.4,;22.56,-20.64,;23.88,-21.41,;22.55,-19.1,;21.22,-18.33,;21.22,-16.79,;19.9,-19.11,;18.57,-18.34,;17.23,-19.1,;15.9,-18.33,;15.9,-16.79,;17.23,-16.02,;18.57,-16.79,;19.91,-16.02,;14.57,-19.09,;14.56,-20.65,;13.21,-21.42,;13.21,-22.96,;11.87,-20.64,;11.88,-19.08,;10.54,-18.32,;9.21,-19.09,;7.87,-18.32,;9.21,-20.64,;10.54,-21.41,;10.54,-22.95,;13.22,-18.3,;19.9,-20.64,;18.58,-21.4,)| Show InChI InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-33,35-37H | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of rat cloned sPLA2-1B expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Group 10 secretory phospholipase A2
(Homo sapiens (Human)) | BDBM50183247
(2-{4-[3-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1cccc(c1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(33-27-10-3-1-8-23(25)27)20-14-12-19(13-15-20)21-6-5-7-22(16-21)30-18-26(32)24-9-2-4-11-28(24)34-30/h1-18H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned sPLA2-10 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Group 10 secretory phospholipase A2
(Homo sapiens (Human)) | BDBM50183245
(6-[4-(4-Oxo-4H-chromen-2-yl)-phenyl]-2-phenyl-chro...)Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1ccc2oc(cc(=O)c2c1)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-25-17-30(33-27-9-5-4-8-23(25)27)21-12-10-19(11-13-21)22-14-15-28-24(16-22)26(32)18-29(34-28)20-6-2-1-3-7-20/h1-18H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned sPLA2-10 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Phospholipase A2
(Rattus norvegicus) | BDBM50183250
(2-(3-(4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)pheno...)Show SMILES Oc1cc2oc(cc(O)c2c(=O)c1)-c1ccc(Oc2cc(ccc2O)-c2cc(O)c3c(cc(O)cc3=O)o2)cc1 Show InChI InChI=1S/C30H18O10/c31-16-8-20(34)29-22(36)12-24(39-27(29)10-16)14-1-4-18(5-2-14)38-26-7-15(3-6-19(26)33)25-13-23(37)30-21(35)9-17(32)11-28(30)40-25/h1-13,31-33,36-37H | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of rat cloned sPLA2-1B expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Group 10 secretory phospholipase A2
(Homo sapiens (Human)) | BDBM50183250
(2-(3-(4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)pheno...)Show SMILES Oc1cc2oc(cc(O)c2c(=O)c1)-c1ccc(Oc2cc(ccc2O)-c2cc(O)c3c(cc(O)cc3=O)o2)cc1 Show InChI InChI=1S/C30H18O10/c31-16-8-20(34)29-22(36)12-24(39-27(29)10-16)14-1-4-18(5-2-14)38-26-7-15(3-6-19(26)33)25-13-23(37)30-21(35)9-17(32)11-28(30)40-25/h1-13,31-33,36-37H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned sPLA2-10 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Group 10 secretory phospholipase A2
(Homo sapiens (Human)) | BDBM50183244
(3-(4-(4-oxo-4H-chromen-2-yl)phenyl)-2-phenyl-4H-ch...)Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-24-18-27(33-25-12-6-4-10-22(24)25)19-14-16-20(17-15-19)28-29(32)23-11-5-7-13-26(23)34-30(28)21-8-2-1-3-9-21/h1-18H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned sPLA2-10 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Group 10 secretory phospholipase A2
(Homo sapiens (Human)) | BDBM50129952
(2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-c...)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1 |(13.25,-26.01,;14.59,-25.24,;14.59,-23.7,;15.92,-22.93,;17.26,-23.7,;17.26,-25.24,;15.93,-26.01,;18.58,-22.93,;19.91,-23.69,;21.23,-22.92,;22.57,-23.69,;21.22,-21.4,;22.56,-20.64,;23.88,-21.41,;22.55,-19.1,;21.22,-18.33,;21.22,-16.79,;19.9,-19.11,;18.57,-18.34,;17.23,-19.1,;15.9,-18.33,;15.9,-16.79,;17.23,-16.02,;18.57,-16.79,;19.91,-16.02,;14.57,-19.09,;14.56,-20.65,;13.21,-21.42,;13.21,-22.96,;11.87,-20.64,;11.88,-19.08,;10.54,-18.32,;9.21,-19.09,;7.87,-18.32,;9.21,-20.64,;10.54,-21.41,;10.54,-22.95,;13.22,-18.3,;19.9,-20.64,;18.58,-21.4,)| Show InChI InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-33,35-37H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned sPLA2-10 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Group 10 secretory phospholipase A2
(Homo sapiens (Human)) | BDBM50183249
(2,2'-Diphenyl-[6,6']bichromenyl-4,4'-dione | CHEMB...)Show SMILES O=c1cc(oc2ccc(cc12)-c1ccc2oc(cc(=O)c2c1)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(19-7-3-1-4-8-19)33-27-13-11-21(15-23(25)27)22-12-14-28-24(16-22)26(32)18-30(34-28)20-9-5-2-6-10-20/h1-18H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned sPLA2-10 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50183250
(2-(3-(4-(5,7-dihydroxy-4-oxo-4H-chromen-2-yl)pheno...)Show SMILES Oc1cc2oc(cc(O)c2c(=O)c1)-c1ccc(Oc2cc(ccc2O)-c2cc(O)c3c(cc(O)cc3=O)o2)cc1 Show InChI InChI=1S/C30H18O10/c31-16-8-20(34)29-22(36)12-24(39-27(29)10-16)14-1-4-18(5-2-14)38-26-7-15(3-6-19(26)33)25-13-23(37)30-21(35)9-17(32)11-28(30)40-25/h1-13,31-33,36-37H | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned cPLA2 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Phospholipase A2
(Rattus norvegicus) | BDBM50183248
(2-{4-[4-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1ccc(cc1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(33-27-7-3-1-5-23(25)27)21-13-9-19(10-14-21)20-11-15-22(16-12-20)30-18-26(32)24-6-2-4-8-28(24)34-30/h1-18H | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of rat cloned sPLA2-1B expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Phospholipase A2
(Rattus norvegicus) | BDBM50183244
(3-(4-(4-oxo-4H-chromen-2-yl)phenyl)-2-phenyl-4H-ch...)Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1c(oc2ccccc2c1=O)-c1ccccc1 Show InChI InChI=1S/C30H18O4/c31-24-18-27(33-25-12-6-4-10-22(24)25)19-14-16-20(17-15-19)28-29(32)23-11-5-7-13-26(23)34-30(28)21-8-2-1-3-9-21/h1-18H | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of rat cloned sPLA2-1B expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Phospholipase A2
(Rattus norvegicus) | BDBM50183247
(2-{4-[3-(4-oxo-4H-chromen-2-yl)phenyl]phenyl}-4H-c...)Show SMILES O=c1cc(oc2ccccc12)-c1ccc(cc1)-c1cccc(c1)-c1cc(=O)c2ccccc2o1 Show InChI InChI=1S/C30H18O4/c31-25-17-29(33-27-10-3-1-8-23(25)27)20-14-12-19(13-15-20)21-6-5-7-22(16-21)30-18-26(32)24-9-2-4-11-28(24)34-30/h1-18H | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of rat cloned sPLA2-1B expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
Cytosolic phospholipase A2
(Homo sapiens (Human)) | BDBM50129952
(2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-c...)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1 |(13.25,-26.01,;14.59,-25.24,;14.59,-23.7,;15.92,-22.93,;17.26,-23.7,;17.26,-25.24,;15.93,-26.01,;18.58,-22.93,;19.91,-23.69,;21.23,-22.92,;22.57,-23.69,;21.22,-21.4,;22.56,-20.64,;23.88,-21.41,;22.55,-19.1,;21.22,-18.33,;21.22,-16.79,;19.9,-19.11,;18.57,-18.34,;17.23,-19.1,;15.9,-18.33,;15.9,-16.79,;17.23,-16.02,;18.57,-16.79,;19.91,-16.02,;14.57,-19.09,;14.56,-20.65,;13.21,-21.42,;13.21,-22.96,;11.87,-20.64,;11.88,-19.08,;10.54,-18.32,;9.21,-19.09,;7.87,-18.32,;9.21,-20.64,;10.54,-21.41,;10.54,-22.95,;13.22,-18.3,;19.9,-20.64,;18.58,-21.4,)| Show InChI InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-33,35-37H | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Yeungnam University
Curated by ChEMBL
| Assay Description
Inhibition of human cloned cPLA2 expressed in HEK293 cells |
Bioorg Med Chem 15: 7138-43 (2007)
Article DOI: 10.1016/j.bmc.2007.07.054
BindingDB Entry DOI: 10.7270/Q2WM1D5G |
More data for this
Ligand-Target Pair | |
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