Found 28 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223615
(3-bromo-5-cyclohexyl-N-(pyridin-3-ylmethyl)pyrazol...)Show InChI InChI=1S/C18H20BrN5/c19-15-12-22-24-17(21-11-13-5-4-8-20-10-13)9-16(23-18(15)24)14-6-2-1-3-7-14/h4-5,8-10,12,14,21H,1-3,6-7,11H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223602
(CHEMBL442802 | N-(2-(5-phenyl-7-(pyridin-3-ylmethy...)Show SMILES CC(=O)NCCSc1cnn2c(NCc3cccnc3)cc(nc12)-c1ccccc1 Show InChI InChI=1S/C22H22N6OS/c1-16(29)24-10-11-30-20-15-26-28-21(25-14-17-6-5-9-23-13-17)12-19(27-22(20)28)18-7-3-2-4-8-18/h2-9,12-13,15,25H,10-11,14H2,1H3,(H,24,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223587
(3-bromo-5-(2-chlorophenyl)-N-((pyridin-3-yloxy)met...)Show InChI InChI=1S/C18H13BrClN5O/c19-14-10-23-25-17(22-11-26-12-4-3-7-21-9-12)8-16(24-18(14)25)13-5-1-2-6-15(13)20/h1-10,22H,11H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223567
(3-bromo-5-(2-chlorophenyl)-N-(pyridin-3-ylmethyl)p...)Show InChI InChI=1S/C18H13BrClN5/c19-14-11-23-25-17(22-10-12-4-3-7-21-9-12)8-16(24-18(14)25)13-5-1-2-6-15(13)20/h1-9,11,22H,10H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223590
(3-bromo-5-(2-fluorophenyl)-N-((pyridin-3-yloxy)met...)Show InChI InChI=1S/C18H13BrFN5O/c19-14-10-23-25-17(22-11-26-12-4-3-7-21-9-12)8-16(24-18(14)25)13-5-1-2-6-15(13)20/h1-10,22H,11H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223583
(3-bromo-5-(piperidin-3-yl)-N-(pyridin-3-ylmethyl)p...)Show SMILES Brc1cnn2c(NCc3cccnc3)cc(nc12)C1CCCNC1 |w:18.20| Show InChI InChI=1S/C17H19BrN6/c18-14-11-22-24-16(21-9-12-3-1-5-19-8-12)7-15(23-17(14)24)13-4-2-6-20-10-13/h1,3,5,7-8,11,13,20-21H,2,4,6,9-10H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223580
(3-bromo-5-(2-chlorophenyl)-N-methylpyrazolo[1,5-a]...)Show InChI InChI=1S/C13H10BrClN4/c1-16-12-6-11(8-4-2-3-5-10(8)15)18-13-9(14)7-17-19(12)13/h2-7,16H,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 247 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223591
(3-bromo-5-(furan-2-yl)-N-(pyridin-3-ylmethyl)pyraz...)Show InChI InChI=1S/C16H12BrN5O/c17-12-10-20-22-15(19-9-11-3-1-5-18-8-11)7-13(21-16(12)22)14-4-2-6-23-14/h1-8,10,19H,9H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 310 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223578
(3-bromo-5-(piperidin-4-yl)-N-(pyridin-3-ylmethyl)p...)Show InChI InChI=1S/C17H19BrN6/c18-14-11-22-24-16(21-10-12-2-1-5-20-9-12)8-15(23-17(14)24)13-3-6-19-7-4-13/h1-2,5,8-9,11,13,19,21H,3-4,6-7,10H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223594
(3-bromo-5-isopropyl-N-(pyridin-3-ylmethyl)pyrazolo...)Show InChI InChI=1S/C15H16BrN5/c1-10(2)13-6-14(18-8-11-4-3-5-17-7-11)21-15(20-13)12(16)9-19-21/h3-7,9-10,18H,8H2,1-2H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223593
(3-bromo-5-(2-chlorophenyl)-N-(4-(methylsulfonyl)ph...)Show SMILES CS(=O)(=O)c1ccc(Nc2cc(nc3c(Br)cnn23)-c2ccccc2Cl)cc1 Show InChI InChI=1S/C19H14BrClN4O2S/c1-28(26,27)13-8-6-12(7-9-13)23-18-10-17(14-4-2-3-5-16(14)21)24-19-15(20)11-22-25(18)19/h2-11,23H,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223581
(3-bromo-N-(pyridin-3-ylmethyl)-5-(thiophen-2-yl)py...)Show InChI InChI=1S/C16H12BrN5S/c17-12-10-20-22-15(19-9-11-3-1-5-18-8-11)7-13(21-16(12)22)14-4-2-6-23-14/h1-8,10,19H,9H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223595
(1-(3-bromo-7-(pyridin-3-ylmethylamino)pyrazolo[1,5...)Show InChI InChI=1S/C14H14BrN5O/c1-9(21)12-5-13(17-7-10-3-2-4-16-6-10)20-14(19-12)11(15)8-18-20/h2-6,8-9,17,21H,7H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223586
(3-bromo-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,...)Show InChI InChI=1S/C18H14BrN5/c19-15-12-22-24-17(21-11-13-5-4-8-20-10-13)9-16(23-18(15)24)14-6-2-1-3-7-14/h1-10,12,21H,11H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223609
(3-bromo-5-phenyl-N-((pyridin-3-yloxy)methyl)pyrazo...)Show InChI InChI=1S/C18H14BrN5O/c19-15-11-22-24-17(21-12-25-14-7-4-8-20-10-14)9-16(23-18(15)24)13-5-2-1-3-6-13/h1-11,21H,12H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223568
(CHEMBL250183 | ethyl 3-bromo-7-(pyridin-3-ylmethyl...)Show InChI InChI=1S/C15H14BrN5O2/c1-2-23-15(22)12-6-13(18-8-10-4-3-5-17-7-10)21-14(20-12)11(16)9-19-21/h3-7,9,18H,2,8H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 790 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223608
(3-bromo-5-ethyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5...)Show InChI InChI=1S/C14H14BrN5/c1-2-11-6-13(17-8-10-4-3-5-16-7-10)20-14(19-11)12(15)9-18-20/h3-7,9,17H,2,8H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223605
(2-(5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,...)Show InChI InChI=1S/C20H16N6/c21-9-8-17-14-24-26-19(23-13-15-5-4-10-22-12-15)11-18(25-20(17)26)16-6-2-1-3-7-16/h1-7,10-12,14,23H,8,13H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223573
(3-bromo-5-cyclopropyl-N-(pyridin-3-ylmethyl)pyrazo...)Show InChI InChI=1S/C15H14BrN5/c16-12-9-19-21-14(18-8-10-2-1-5-17-7-10)6-13(11-3-4-11)20-15(12)21/h1-2,5-7,9,11,18H,3-4,8H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223577
(3-bromo-5-(methylthio)-N-(pyridin-3-ylmethyl)pyraz...)Show InChI InChI=1S/C13H12BrN5S/c1-20-12-5-11(16-7-9-3-2-4-15-6-9)19-13(18-12)10(14)8-17-19/h2-6,8,16H,7H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 1.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223601
(3-bromo-5-methoxy-N-(pyridin-3-ylmethyl)pyrazolo[1...)Show InChI InChI=1S/C13H12BrN5O/c1-20-12-5-11(16-7-9-3-2-4-15-6-9)19-13(18-12)10(14)8-17-19/h2-6,8,16H,7H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 1.41E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223592
(3-(methylthio)-5-phenyl-N-(pyridin-3-ylmethyl)pyra...)Show InChI InChI=1S/C19H17N5S/c1-25-17-13-22-24-18(21-12-14-6-5-9-20-11-14)10-16(23-19(17)24)15-7-3-2-4-8-15/h2-11,13,21H,12H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223607
(3-ethyl-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[1,...)Show InChI InChI=1S/C20H19N5/c1-2-16-14-23-25-19(22-13-15-7-6-10-21-12-15)11-18(24-20(16)25)17-8-4-3-5-9-17/h3-12,14,22H,2,13H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223599
(3-bromo-5-methyl-N-(pyridin-3-ylmethyl)pyrazolo[1,...)Show InChI InChI=1S/C13H12BrN5/c1-9-5-12(16-7-10-3-2-4-15-6-10)19-13(18-9)11(14)8-17-19/h2-6,8,16H,7H2,1H3 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 3.53E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223610
(3-bromo-N5-methyl-N7-(pyridin-3-ylmethyl)pyrazolo[...)Show InChI InChI=1S/C13H13BrN6/c1-15-11-5-12(17-7-9-3-2-4-16-6-9)20-13(19-11)10(14)8-18-20/h2-6,8,17H,7H2,1H3,(H,15,19) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 4.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223576
(3-ethynyl-5-phenyl-N-(pyridin-3-ylmethyl)pyrazolo[...)Show InChI InChI=1S/C20H15N5/c1-2-16-14-23-25-19(22-13-15-7-6-10-21-12-15)11-18(24-20(16)25)17-8-4-3-5-9-17/h1,3-12,14,22H,13H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223570
(3-bromo-5-(2-fluorophenyl)-N-phenylpyrazolo[1,5-a]...)Show InChI InChI=1S/C18H12BrFN4/c19-14-11-21-24-17(22-12-6-2-1-3-7-12)10-16(23-18(14)24)13-8-4-5-9-15(13)20/h1-11,22H | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.33E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50223582
(CHEMBL249947 | N-benzyl-3-bromo-5-(2-fluorophenyl)...)Show InChI InChI=1S/C19H14BrFN4/c20-15-12-23-25-18(22-11-13-6-2-1-3-7-13)10-17(24-19(15)25)14-8-4-5-9-16(14)21/h1-10,12,22H,11H2 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| Assay Description
Inhibition of human GSK3beta |
Bioorg Med Chem Lett 17: 6220-3 (2007)
Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND |
More data for this
Ligand-Target Pair | |
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