Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase (Toxoplasma gondii) | BDBM13336 (4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Tulane University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Toxoplasma gondii recombinant MAPK1 expressed in Escherichia coli | Antimicrob Agents Chemother 51: 4324-8 (2007) Article DOI: 10.1128/AAC.00680-07 BindingDB Entry DOI: 10.7270/Q2Q52QJG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase (Toxoplasma gondii) | BDBM50295553 (4-(4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(pyridi...) | UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
Tulane University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Toxoplasma gondii recombinant MAPK1 expressed in Escherichia coli | Antimicrob Agents Chemother 51: 4324-8 (2007) Article DOI: 10.1128/AAC.00680-07 BindingDB Entry DOI: 10.7270/Q2Q52QJG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM13531 (4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridy...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Tulane University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant p38alpha assessed as [gamma33P]ATP utilization by microplate scintillation counting | Antimicrob Agents Chemother 51: 4324-8 (2007) Article DOI: 10.1128/AAC.00680-07 BindingDB Entry DOI: 10.7270/Q2Q52QJG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM50295553 (4-(4-(4-fluorophenyl)-1-(3-phenylpropyl)-5-(pyridi...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tulane University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant p38alpha assessed as [gamma33P]ATP utilization by microplate scintillation counting | Antimicrob Agents Chemother 51: 4324-8 (2007) Article DOI: 10.1128/AAC.00680-07 BindingDB Entry DOI: 10.7270/Q2Q52QJG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 14 (Homo sapiens (Human)) | BDBM13336 (4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tulane University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human recombinant p38alpha assessed as [gamma33P]ATP utilization by microplate scintillation counting | Antimicrob Agents Chemother 51: 4324-8 (2007) Article DOI: 10.1128/AAC.00680-07 BindingDB Entry DOI: 10.7270/Q2Q52QJG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |