Found 86 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225411
((R)-2-(N-((6-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)nc1)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22FN3O5S/c1-12(2)17(18(23)21-24)22(11-13-4-9-16(19)20-10-13)28(25,26)15-7-5-14(27-3)6-8-15/h4-10,12,17,24H,11H2,1-3H3,(H,21,23)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225407
((R)-2-(4-(2-fluoroethoxy)phenylsulphonamido-N-(pyr...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(OCCF)cc1)C(=O)NO Show InChI InChI=1S/C19H24FN3O5S/c1-14(2)18(19(24)22-25)23(13-15-4-3-10-21-12-15)29(26,27)17-7-5-16(6-8-17)28-11-9-20/h3-8,10,12,14,18,25H,9,11,13H2,1-2H3,(H,22,24)/t18-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225411
((R)-2-(N-((6-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)nc1)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22FN3O5S/c1-12(2)17(18(23)21-24)22(11-13-4-9-16(19)20-10-13)28(25,26)15-7-5-14(27-3)6-8-15/h4-10,12,17,24H,11H2,1-3H3,(H,21,23)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225411
((R)-2-(N-((6-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)nc1)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22FN3O5S/c1-12(2)17(18(23)21-24)22(11-13-4-9-16(19)20-10-13)28(25,26)15-7-5-14(27-3)6-8-15/h4-10,12,17,24H,11H2,1-3H3,(H,21,23)/t17-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM8465
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225409
((R)-2-(N-((6-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)nc1)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22BrN3O5S/c1-12(2)17(18(23)21-24)22(11-13-4-9-16(19)20-10-13)28(25,26)15-7-5-14(27-3)6-8-15/h4-10,12,17,24H,11H2,1-3H3,(H,21,23)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225397
((R)-2-(N-benzyl-4-(2-fluoroethoxy)phenylsulfonamid...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCF)cc1)C(=O)NO Show InChI InChI=1S/C20H25FN2O5S/c1-15(2)19(20(24)22-25)23(14-16-6-4-3-5-7-16)29(26,27)18-10-8-17(9-11-18)28-13-12-21/h3-11,15,19,25H,12-14H2,1-2H3,(H,22,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225407
((R)-2-(4-(2-fluoroethoxy)phenylsulphonamido-N-(pyr...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(OCCF)cc1)C(=O)NO Show InChI InChI=1S/C19H24FN3O5S/c1-14(2)18(19(24)22-25)23(13-15-4-3-10-21-12-15)29(26,27)17-7-5-16(6-8-17)28-11-9-20/h3-8,10,12,14,18,25H,9,11,13H2,1-2H3,(H,22,24)/t18-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM8465
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225401
((R)-2-(N-benzyl-4-(2-iodoethoxy)phenylsulphonamido...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCI)cc1)C(=O)NO Show InChI InChI=1S/C20H25IN2O5S/c1-15(2)19(20(24)22-25)23(14-16-6-4-3-5-7-16)29(26,27)18-10-8-17(9-11-18)28-13-12-21/h3-11,15,19,25H,12-14H2,1-2H3,(H,22,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225407
((R)-2-(4-(2-fluoroethoxy)phenylsulphonamido-N-(pyr...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(OCCF)cc1)C(=O)NO Show InChI InChI=1S/C19H24FN3O5S/c1-14(2)18(19(24)22-25)23(13-15-4-3-10-21-12-15)29(26,27)17-7-5-16(6-8-17)28-11-9-20/h3-8,10,12,14,18,25H,9,11,13H2,1-2H3,(H,22,24)/t18-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225397
((R)-2-(N-benzyl-4-(2-fluoroethoxy)phenylsulfonamid...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCF)cc1)C(=O)NO Show InChI InChI=1S/C20H25FN2O5S/c1-15(2)19(20(24)22-25)23(14-16-6-4-3-5-7-16)29(26,27)18-10-8-17(9-11-18)28-13-12-21/h3-11,15,19,25H,12-14H2,1-2H3,(H,22,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM8465
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225407
((R)-2-(4-(2-fluoroethoxy)phenylsulphonamido-N-(pyr...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(OCCF)cc1)C(=O)NO Show InChI InChI=1S/C19H24FN3O5S/c1-14(2)18(19(24)22-25)23(13-15-4-3-10-21-12-15)29(26,27)17-7-5-16(6-8-17)28-11-9-20/h3-8,10,12,14,18,25H,9,11,13H2,1-2H3,(H,22,24)/t18-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225411
((R)-2-(N-((6-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)nc1)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22FN3O5S/c1-12(2)17(18(23)21-24)22(11-13-4-9-16(19)20-10-13)28(25,26)15-7-5-14(27-3)6-8-15/h4-10,12,17,24H,11H2,1-3H3,(H,21,23)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225412
((R)-2-(4-nitrophenylsulfonamido-N-(pyridin-3-ylmet...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NO Show InChI InChI=1S/C17H20N4O6S/c1-12(2)16(17(22)19-23)20(11-13-4-3-9-18-10-13)28(26,27)15-7-5-14(6-8-15)21(24)25/h3-10,12,16,23H,11H2,1-2H3,(H,19,22)/t16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225401
((R)-2-(N-benzyl-4-(2-iodoethoxy)phenylsulphonamido...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCI)cc1)C(=O)NO Show InChI InChI=1S/C20H25IN2O5S/c1-15(2)19(20(24)22-25)23(14-16-6-4-3-5-7-16)29(26,27)18-10-8-17(9-11-18)28-13-12-21/h3-11,15,19,25H,12-14H2,1-2H3,(H,22,24)/t19-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225399
((R)-2-(N-benzyl-4-(dimethylamino)phenylsulphonamid...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)N(C)C)C(=O)NO Show InChI InChI=1S/C20H27N3O4S/c1-15(2)19(20(24)21-25)23(14-16-8-6-5-7-9-16)28(26,27)18-12-10-17(11-13-18)22(3)4/h5-13,15,19,25H,14H2,1-4H3,(H,21,24)/t19-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225397
((R)-2-(N-benzyl-4-(2-fluoroethoxy)phenylsulfonamid...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCF)cc1)C(=O)NO Show InChI InChI=1S/C20H25FN2O5S/c1-15(2)19(20(24)22-25)23(14-16-6-4-3-5-7-16)29(26,27)18-10-8-17(9-11-18)28-13-12-21/h3-11,15,19,25H,12-14H2,1-2H3,(H,22,24)/t19-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225396
((R)-2-(N-benzyl-4-fluorophenylsulphonamido)-N-hydr...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(F)cc1)C(=O)NO Show InChI InChI=1S/C18H21FN2O4S/c1-13(2)17(18(22)20-23)21(12-14-6-4-3-5-7-14)26(24,25)16-10-8-15(19)9-11-16/h3-11,13,17,23H,12H2,1-2H3,(H,20,22)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225412
((R)-2-(4-nitrophenylsulfonamido-N-(pyridin-3-ylmet...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NO Show InChI InChI=1S/C17H20N4O6S/c1-12(2)16(17(22)19-23)20(11-13-4-3-9-18-10-13)28(26,27)15-7-5-14(6-8-15)21(24)25/h3-10,12,16,23H,11H2,1-2H3,(H,19,22)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225410
((R)-2-(N-((2-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1F)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22FN3O5S/c1-12(2)16(18(23)21-24)22(11-13-5-4-10-20-17(13)19)28(25,26)15-8-6-14(27-3)7-9-15/h4-10,12,16,24H,11H2,1-3H3,(H,21,23)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225410
((R)-2-(N-((2-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1F)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22FN3O5S/c1-12(2)16(18(23)21-24)22(11-13-5-4-10-20-17(13)19)28(25,26)15-8-6-14(27-3)7-9-15/h4-10,12,16,24H,11H2,1-3H3,(H,21,23)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225409
((R)-2-(N-((6-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)nc1)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22BrN3O5S/c1-12(2)17(18(23)21-24)22(11-13-4-9-16(19)20-10-13)28(25,26)15-7-5-14(27-3)6-8-15/h4-10,12,17,24H,11H2,1-3H3,(H,21,23)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225401
((R)-2-(N-benzyl-4-(2-iodoethoxy)phenylsulphonamido...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCI)cc1)C(=O)NO Show InChI InChI=1S/C20H25IN2O5S/c1-15(2)19(20(24)22-25)23(14-16-6-4-3-5-7-16)29(26,27)18-10-8-17(9-11-18)28-13-12-21/h3-11,15,19,25H,12-14H2,1-2H3,(H,22,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225409
((R)-2-(N-((6-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)nc1)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22BrN3O5S/c1-12(2)17(18(23)21-24)22(11-13-4-9-16(19)20-10-13)28(25,26)15-7-5-14(27-3)6-8-15/h4-10,12,17,24H,11H2,1-3H3,(H,21,23)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225409
((R)-2-(N-((6-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)nc1)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22BrN3O5S/c1-12(2)17(18(23)21-24)22(11-13-4-9-16(19)20-10-13)28(25,26)15-7-5-14(27-3)6-8-15/h4-10,12,17,24H,11H2,1-3H3,(H,21,23)/t17-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225405
((R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1Br)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22BrN3O5S/c1-12(2)16(18(23)21-24)22(11-13-5-4-10-20-17(13)19)28(25,26)15-8-6-14(27-3)7-9-15/h4-10,12,16,24H,11H2,1-3H3,(H,21,23)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM8465
((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO |r| Show InChI InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225410
((R)-2-(N-((2-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1F)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22FN3O5S/c1-12(2)16(18(23)21-24)22(11-13-5-4-10-20-17(13)19)28(25,26)15-8-6-14(27-3)7-9-15/h4-10,12,16,24H,11H2,1-3H3,(H,21,23)/t16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225397
((R)-2-(N-benzyl-4-(2-fluoroethoxy)phenylsulfonamid...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCF)cc1)C(=O)NO Show InChI InChI=1S/C20H25FN2O5S/c1-15(2)19(20(24)22-25)23(14-16-6-4-3-5-7-16)29(26,27)18-10-8-17(9-11-18)28-13-12-21/h3-11,15,19,25H,12-14H2,1-2H3,(H,22,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225410
((R)-2-(N-((2-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1F)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22FN3O5S/c1-12(2)16(18(23)21-24)22(11-13-5-4-10-20-17(13)19)28(25,26)15-8-6-14(27-3)7-9-15/h4-10,12,16,24H,11H2,1-3H3,(H,21,23)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225405
((R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1Br)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22BrN3O5S/c1-12(2)16(18(23)21-24)22(11-13-5-4-10-20-17(13)19)28(25,26)15-8-6-14(27-3)7-9-15/h4-10,12,16,24H,11H2,1-3H3,(H,21,23)/t16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225401
((R)-2-(N-benzyl-4-(2-iodoethoxy)phenylsulphonamido...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCI)cc1)C(=O)NO Show InChI InChI=1S/C20H25IN2O5S/c1-15(2)19(20(24)22-25)23(14-16-6-4-3-5-7-16)29(26,27)18-10-8-17(9-11-18)28-13-12-21/h3-11,15,19,25H,12-14H2,1-2H3,(H,22,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225405
((R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1Br)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22BrN3O5S/c1-12(2)16(18(23)21-24)22(11-13-5-4-10-20-17(13)19)28(25,26)15-8-6-14(27-3)7-9-15/h4-10,12,16,24H,11H2,1-3H3,(H,21,23)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225405
((R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1Br)[C@H](C(C)C)C(=O)NO Show InChI InChI=1S/C18H22BrN3O5S/c1-12(2)16(18(23)21-24)22(11-13-5-4-10-20-17(13)19)28(25,26)15-8-6-14(27-3)7-9-15/h4-10,12,16,24H,11H2,1-3H3,(H,21,23)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 103 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225399
((R)-2-(N-benzyl-4-(dimethylamino)phenylsulphonamid...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)N(C)C)C(=O)NO Show InChI InChI=1S/C20H27N3O4S/c1-15(2)19(20(24)21-25)23(14-16-8-6-5-7-9-16)28(26,27)18-12-10-17(11-13-18)22(3)4/h5-13,15,19,25H,14H2,1-4H3,(H,21,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 105 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225413
((R)-2-(4-fluorophenylsulphonamido-N-(pyridin-3-ylm...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(F)cc1)C(=O)NO Show InChI InChI=1S/C17H20FN3O4S/c1-12(2)16(17(22)20-23)21(11-13-4-3-9-19-10-13)26(24,25)15-7-5-14(18)6-8-15/h3-10,12,16,23H,11H2,1-2H3,(H,20,22)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225404
((R)-2-(N-benzyl-4-(2-iodoethoxy)phenylsulphonamido...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCI)cc1)C(O)=O Show InChI InChI=1S/C20H24INO5S/c1-15(2)19(20(23)24)22(14-16-6-4-3-5-7-16)28(25,26)18-10-8-17(9-11-18)27-13-12-21/h3-11,15,19H,12-14H2,1-2H3,(H,23,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 207 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225413
((R)-2-(4-fluorophenylsulphonamido-N-(pyridin-3-ylm...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(F)cc1)C(=O)NO Show InChI InChI=1S/C17H20FN3O4S/c1-12(2)16(17(22)20-23)21(11-13-4-3-9-19-10-13)26(24,25)15-7-5-14(18)6-8-15/h3-10,12,16,23H,11H2,1-2H3,(H,20,22)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 228 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225396
((R)-2-(N-benzyl-4-fluorophenylsulphonamido)-N-hydr...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(F)cc1)C(=O)NO Show InChI InChI=1S/C18H21FN2O4S/c1-13(2)17(18(22)20-23)21(12-14-6-4-3-5-7-14)26(24,25)16-10-8-15(19)9-11-16/h3-11,13,17,23H,12H2,1-2H3,(H,20,22)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 239 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225396
((R)-2-(N-benzyl-4-fluorophenylsulphonamido)-N-hydr...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(F)cc1)C(=O)NO Show InChI InChI=1S/C18H21FN2O4S/c1-13(2)17(18(22)20-23)21(12-14-6-4-3-5-7-14)26(24,25)16-10-8-15(19)9-11-16/h3-11,13,17,23H,12H2,1-2H3,(H,20,22)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 281 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225399
((R)-2-(N-benzyl-4-(dimethylamino)phenylsulphonamid...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)N(C)C)C(=O)NO Show InChI InChI=1S/C20H27N3O4S/c1-15(2)19(20(24)21-25)23(14-16-8-6-5-7-9-16)28(26,27)18-12-10-17(11-13-18)22(3)4/h5-13,15,19,25H,14H2,1-4H3,(H,21,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 335 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225396
((R)-2-(N-benzyl-4-fluorophenylsulphonamido)-N-hydr...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(F)cc1)C(=O)NO Show InChI InChI=1S/C18H21FN2O4S/c1-13(2)17(18(22)20-23)21(12-14-6-4-3-5-7-14)26(24,25)16-10-8-15(19)9-11-16/h3-11,13,17,23H,12H2,1-2H3,(H,20,22)/t17-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 384 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225413
((R)-2-(4-fluorophenylsulphonamido-N-(pyridin-3-ylm...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(F)cc1)C(=O)NO Show InChI InChI=1S/C17H20FN3O4S/c1-12(2)16(17(22)20-23)21(11-13-4-3-9-19-10-13)26(24,25)15-7-5-14(18)6-8-15/h3-10,12,16,23H,11H2,1-2H3,(H,20,22)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 414 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225413
((R)-2-(4-fluorophenylsulphonamido-N-(pyridin-3-ylm...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(F)cc1)C(=O)NO Show InChI InChI=1S/C17H20FN3O4S/c1-12(2)16(17(22)20-23)21(11-13-4-3-9-19-10-13)26(24,25)15-7-5-14(18)6-8-15/h3-10,12,16,23H,11H2,1-2H3,(H,20,22)/t16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 527 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225399
((R)-2-(N-benzyl-4-(dimethylamino)phenylsulphonamid...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)N(C)C)C(=O)NO Show InChI InChI=1S/C20H27N3O4S/c1-15(2)19(20(24)21-25)23(14-16-8-6-5-7-9-16)28(26,27)18-12-10-17(11-13-18)22(3)4/h5-13,15,19,25H,14H2,1-4H3,(H,21,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 614 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225406
((R)-2-(N-benzyl-4-fluorophenylsulphonamido)-3-meth...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C18H20FNO4S/c1-13(2)17(18(21)22)20(12-14-6-4-3-5-7-14)25(23,24)16-10-8-15(19)9-11-16/h3-11,13,17H,12H2,1-2H3,(H,21,22)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 754 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225412
((R)-2-(4-nitrophenylsulfonamido-N-(pyridin-3-ylmet...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NO Show InChI InChI=1S/C17H20N4O6S/c1-12(2)16(17(22)19-23)20(11-13-4-3-9-18-10-13)28(26,27)15-7-5-14(6-8-15)21(24)25/h3-10,12,16,23H,11H2,1-2H3,(H,19,22)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 756 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225406
((R)-2-(N-benzyl-4-fluorophenylsulphonamido)-3-meth...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C18H20FNO4S/c1-13(2)17(18(21)22)20(12-14-6-4-3-5-7-14)25(23,24)16-10-8-15(19)9-11-16/h3-11,13,17H,12H2,1-2H3,(H,21,22)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 821 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225402
((R)-2-(4-(dimethylamino)phenylsulfonamido-N-(pyrid...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(cc1)N(C)C)C(=O)NO Show InChI InChI=1S/C19H26N4O4S/c1-14(2)18(19(24)21-25)23(13-15-6-5-11-20-12-15)28(26,27)17-9-7-16(8-10-17)22(3)4/h5-12,14,18,25H,13H2,1-4H3,(H,21,24)/t18-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 992 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225402
((R)-2-(4-(dimethylamino)phenylsulfonamido-N-(pyrid...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(cc1)N(C)C)C(=O)NO Show InChI InChI=1S/C19H26N4O4S/c1-14(2)18(19(24)21-25)23(13-15-6-5-11-20-12-15)28(26,27)17-9-7-16(8-10-17)22(3)4/h5-12,14,18,25H,13H2,1-4H3,(H,21,24)/t18-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225408
((R)-2-(N-benzyl-4-(2-fluoroethoxy)phenylsulphonami...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCF)cc1)C(O)=O Show InChI InChI=1S/C20H24FNO5S/c1-15(2)19(20(23)24)22(14-16-6-4-3-5-7-16)28(25,26)18-10-8-17(9-11-18)27-13-12-21/h3-11,15,19H,12-14H2,1-2H3,(H,23,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225402
((R)-2-(4-(dimethylamino)phenylsulfonamido-N-(pyrid...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(cc1)N(C)C)C(=O)NO Show InChI InChI=1S/C19H26N4O4S/c1-14(2)18(19(24)21-25)23(13-15-6-5-11-20-12-15)28(26,27)17-9-7-16(8-10-17)22(3)4/h5-12,14,18,25H,13H2,1-4H3,(H,21,24)/t18-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225402
((R)-2-(4-(dimethylamino)phenylsulfonamido-N-(pyrid...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(cc1)N(C)C)C(=O)NO Show InChI InChI=1S/C19H26N4O4S/c1-14(2)18(19(24)21-25)23(13-15-6-5-11-20-12-15)28(26,27)17-9-7-16(8-10-17)22(3)4/h5-12,14,18,25H,13H2,1-4H3,(H,21,24)/t18-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225404
((R)-2-(N-benzyl-4-(2-iodoethoxy)phenylsulphonamido...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCI)cc1)C(O)=O Show InChI InChI=1S/C20H24INO5S/c1-15(2)19(20(23)24)22(14-16-6-4-3-5-7-16)28(25,26)18-10-8-17(9-11-18)27-13-12-21/h3-11,15,19H,12-14H2,1-2H3,(H,23,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225408
((R)-2-(N-benzyl-4-(2-fluoroethoxy)phenylsulphonami...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCF)cc1)C(O)=O Show InChI InChI=1S/C20H24FNO5S/c1-15(2)19(20(23)24)22(14-16-6-4-3-5-7-16)28(25,26)18-10-8-17(9-11-18)27-13-12-21/h3-11,15,19H,12-14H2,1-2H3,(H,23,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225400
((R)-2-(N-((6-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)nc1)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21BrN2O5S/c1-12(2)17(18(22)23)21(11-13-4-9-16(19)20-10-13)27(24,25)15-7-5-14(26-3)6-8-15/h4-10,12,17H,11H2,1-3H3,(H,22,23)/t17-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225406
((R)-2-(N-benzyl-4-fluorophenylsulphonamido)-3-meth...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C18H20FNO4S/c1-13(2)17(18(21)22)20(12-14-6-4-3-5-7-14)25(23,24)16-10-8-15(19)9-11-16/h3-11,13,17H,12H2,1-2H3,(H,21,22)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225412
((R)-2-(4-nitrophenylsulfonamido-N-(pyridin-3-ylmet...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O)C(=O)NO Show InChI InChI=1S/C17H20N4O6S/c1-12(2)16(17(22)19-23)20(11-13-4-3-9-18-10-13)28(26,27)15-7-5-14(6-8-15)21(24)25/h3-10,12,16,23H,11H2,1-2H3,(H,19,22)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.15E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225408
((R)-2-(N-benzyl-4-(2-fluoroethoxy)phenylsulphonami...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCF)cc1)C(O)=O Show InChI InChI=1S/C20H24FNO5S/c1-15(2)19(20(23)24)22(14-16-6-4-3-5-7-16)28(25,26)18-10-8-17(9-11-18)27-13-12-21/h3-11,15,19H,12-14H2,1-2H3,(H,23,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.59E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225400
((R)-2-(N-((6-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)nc1)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21BrN2O5S/c1-12(2)17(18(22)23)21(11-13-4-9-16(19)20-10-13)27(24,25)15-7-5-14(26-3)6-8-15/h4-10,12,17H,11H2,1-3H3,(H,22,23)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225400
((R)-2-(N-((6-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)nc1)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21BrN2O5S/c1-12(2)17(18(22)23)21(11-13-4-9-16(19)20-10-13)27(24,25)15-7-5-14(26-3)6-8-15/h4-10,12,17H,11H2,1-3H3,(H,22,23)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225400
((R)-2-(N-((6-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Br)nc1)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21BrN2O5S/c1-12(2)17(18(22)23)21(11-13-4-9-16(19)20-10-13)27(24,25)15-7-5-14(26-3)6-8-15/h4-10,12,17H,11H2,1-3H3,(H,22,23)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225395
((R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1Br)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21BrN2O5S/c1-12(2)16(18(22)23)21(11-13-5-4-10-20-17(13)19)27(24,25)15-8-6-14(26-3)7-9-15/h4-10,12,16H,11H2,1-3H3,(H,22,23)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225395
((R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1Br)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21BrN2O5S/c1-12(2)16(18(22)23)21(11-13-5-4-10-20-17(13)19)27(24,25)15-8-6-14(26-3)7-9-15/h4-10,12,16H,11H2,1-3H3,(H,22,23)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225406
((R)-2-(N-benzyl-4-fluorophenylsulphonamido)-3-meth...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C18H20FNO4S/c1-13(2)17(18(21)22)20(12-14-6-4-3-5-7-14)25(23,24)16-10-8-15(19)9-11-16/h3-11,13,17H,12H2,1-2H3,(H,21,22)/t17-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225394
((R)-2-(N-((6-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)nc1)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21FN2O5S/c1-12(2)17(18(22)23)21(11-13-4-9-16(19)20-10-13)27(24,25)15-7-5-14(26-3)6-8-15/h4-10,12,17H,11H2,1-3H3,(H,22,23)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225403
((R)-2-(N-((2-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1F)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21FN2O5S/c1-12(2)16(18(22)23)21(11-13-5-4-10-20-17(13)19)27(24,25)15-8-6-14(26-3)7-9-15/h4-10,12,16H,11H2,1-3H3,(H,22,23)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225414
((R)-2-(N-benzyl-4-(dimethylamino)phenylsulphonamid...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)N(C)C)C(O)=O Show InChI InChI=1S/C20H26N2O4S/c1-15(2)19(20(23)24)22(14-16-8-6-5-7-9-16)27(25,26)18-12-10-17(11-13-18)21(3)4/h5-13,15,19H,14H2,1-4H3,(H,23,24)/t19-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225414
((R)-2-(N-benzyl-4-(dimethylamino)phenylsulphonamid...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)N(C)C)C(O)=O Show InChI InChI=1S/C20H26N2O4S/c1-15(2)19(20(23)24)22(14-16-8-6-5-7-9-16)27(25,26)18-12-10-17(11-13-18)21(3)4/h5-13,15,19H,14H2,1-4H3,(H,23,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225414
((R)-2-(N-benzyl-4-(dimethylamino)phenylsulphonamid...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)N(C)C)C(O)=O Show InChI InChI=1S/C20H26N2O4S/c1-15(2)19(20(23)24)22(14-16-8-6-5-7-9-16)27(25,26)18-12-10-17(11-13-18)21(3)4/h5-13,15,19H,14H2,1-4H3,(H,23,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225403
((R)-2-(N-((2-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1F)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21FN2O5S/c1-12(2)16(18(22)23)21(11-13-5-4-10-20-17(13)19)27(24,25)15-8-6-14(26-3)7-9-15/h4-10,12,16H,11H2,1-3H3,(H,22,23)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225394
((R)-2-(N-((6-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)nc1)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21FN2O5S/c1-12(2)17(18(22)23)21(11-13-4-9-16(19)20-10-13)27(24,25)15-7-5-14(26-3)6-8-15/h4-10,12,17H,11H2,1-3H3,(H,22,23)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225394
((R)-2-(N-((6-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)nc1)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21FN2O5S/c1-12(2)17(18(22)23)21(11-13-4-9-16(19)20-10-13)27(24,25)15-7-5-14(26-3)6-8-15/h4-10,12,17H,11H2,1-3H3,(H,22,23)/t17-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225395
((R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1Br)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21BrN2O5S/c1-12(2)16(18(22)23)21(11-13-5-4-10-20-17(13)19)27(24,25)15-8-6-14(26-3)7-9-15/h4-10,12,16H,11H2,1-3H3,(H,22,23)/t16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225395
((R)-2-(N-((2-bromopyridin-3-yl)methyl)-4-methoxyph...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1Br)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21BrN2O5S/c1-12(2)16(18(22)23)21(11-13-5-4-10-20-17(13)19)27(24,25)15-8-6-14(26-3)7-9-15/h4-10,12,16H,11H2,1-3H3,(H,22,23)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225394
((R)-2-(N-((6-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(F)nc1)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21FN2O5S/c1-12(2)17(18(22)23)21(11-13-4-9-16(19)20-10-13)27(24,25)15-7-5-14(26-3)6-8-15/h4-10,12,17H,11H2,1-3H3,(H,22,23)/t17-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225414
((R)-2-(N-benzyl-4-(dimethylamino)phenylsulphonamid...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)N(C)C)C(O)=O Show InChI InChI=1S/C20H26N2O4S/c1-15(2)19(20(23)24)22(14-16-8-6-5-7-9-16)27(25,26)18-12-10-17(11-13-18)21(3)4/h5-13,15,19H,14H2,1-4H3,(H,23,24)/t19-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225403
((R)-2-(N-((2-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1F)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21FN2O5S/c1-12(2)16(18(22)23)21(11-13-5-4-10-20-17(13)19)27(24,25)15-8-6-14(26-3)7-9-15/h4-10,12,16H,11H2,1-3H3,(H,22,23)/t16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225398
((R)-2-(4-fluorophenylsulphonamido-N-(pyridin-3-ylm...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C17H19FN2O4S/c1-12(2)16(17(21)22)20(11-13-4-3-9-19-10-13)25(23,24)15-7-5-14(18)6-8-15/h3-10,12,16H,11H2,1-2H3,(H,21,22)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50225403
((R)-2-(N-((2-fluoropyridin-3-yl)methyl)-4-methoxyp...)Show SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1F)[C@H](C(C)C)C(O)=O Show InChI InChI=1S/C18H21FN2O5S/c1-12(2)16(18(22)23)21(11-13-5-4-10-20-17(13)19)27(24,25)15-8-6-14(26-3)7-9-15/h4-10,12,16H,11H2,1-3H3,(H,22,23)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP8 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225408
((R)-2-(N-benzyl-4-(2-fluoroethoxy)phenylsulphonami...)Show SMILES CC(C)[C@@H](N(Cc1ccccc1)S(=O)(=O)c1ccc(OCCF)cc1)C(O)=O Show InChI InChI=1S/C20H24FNO5S/c1-15(2)19(20(23)24)22(14-16-6-4-3-5-7-16)28(25,26)18-10-8-17(9-11-18)27-13-12-21/h3-11,15,19H,12-14H2,1-2H3,(H,23,24)/t19-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50225398
((R)-2-(4-fluorophenylsulphonamido-N-(pyridin-3-ylm...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C17H19FN2O4S/c1-12(2)16(17(21)22)20(11-13-4-3-9-19-10-13)25(23,24)15-7-5-14(18)6-8-15/h3-10,12,16H,11H2,1-2H3,(H,21,22)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP9 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50225398
((R)-2-(4-fluorophenylsulphonamido-N-(pyridin-3-ylm...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C17H19FN2O4S/c1-12(2)16(17(21)22)20(11-13-4-3-9-19-10-13)25(23,24)15-7-5-14(18)6-8-15/h3-10,12,16H,11H2,1-2H3,(H,21,22)/t16-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP2 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50225398
((R)-2-(4-fluorophenylsulphonamido-N-(pyridin-3-ylm...)Show SMILES CC(C)[C@@H](N(Cc1cccnc1)S(=O)(=O)c1ccc(F)cc1)C(O)=O Show InChI InChI=1S/C17H19FN2O4S/c1-12(2)16(17(21)22)20(11-13-4-3-9-19-10-13)25(23,24)15-7-5-14(18)6-8-15/h3-10,12,16H,11H2,1-2H3,(H,21,22)/t16-/m1/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University Hospital of the Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
| Assay Description Inhibition of MMP13 |
J Med Chem 50: 5752-64 (2007)
Article DOI: 10.1021/jm0708533 BindingDB Entry DOI: 10.7270/Q2J38TCH |
More data for this Ligand-Target Pair | |