Affinity Data by PubMed id=17975902

PubMed code 17975902

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Farnesyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50225999 (1-fluoro-2-(3-pyridinyl)-ethylidene-1,1-bisphospho...) Show SMILES OP(O)(=O)C(F)(Cc1cccnc1)P(O)(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	16.4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)				J Med Chem 50: 5967-75 (2007) Article DOI: 10.1021/jm0702884 BindingDB Entry DOI: 10.7270/Q27944DF
University of Southern California Curated by ChEMBL					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50138725 ((1-phosphono-2-pyridin-3-yl-ethyl)-phosphonic acid...) Show SMILES OP(O)(=O)C(Cc1cccnc1)P(O)(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34.2	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)				J Med Chem 50: 5967-75 (2007) Article DOI: 10.1021/jm0702884 BindingDB Entry DOI: 10.7270/Q27944DF
University of Southern California Curated by ChEMBL					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50225995 (1-chloro-2-(3-pyridinyl)-ethylidene-1,1-bisphospho...) Show SMILES OP(O)(=O)C(Cl)(Cc1cccnc1)P(O)(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	94.6	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)				J Med Chem 50: 5967-75 (2007) Article DOI: 10.1021/jm0702884 BindingDB Entry DOI: 10.7270/Q27944DF
University of Southern California Curated by ChEMBL					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50225997 (1-bromo-2-(3-pyridinyl)-ethylidene-1,1-bisphosphon...) Show SMILES OP(O)(=O)C(Br)(Cc1cccnc1)P(O)(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)				J Med Chem 50: 5967-75 (2007) Article DOI: 10.1021/jm0702884 BindingDB Entry DOI: 10.7270/Q27944DF
University of Southern California Curated by ChEMBL					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50226001 (2-bromo-3-(3-pyridinyl)-2-phosphonopropionic acid ...) Show SMILES OC(=O)C(Br)(Cc1cccnc1)P(O)(O)=O \|w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)				J Med Chem 50: 5967-75 (2007) Article DOI: 10.1021/jm0702884 BindingDB Entry DOI: 10.7270/Q27944DF
University of Southern California Curated by ChEMBL					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50226002 ((R)-2-hydroxy-2-phosphono-3-(pyridin-3-yl)propanoi...) Show SMILES OC(=O)C(O)(Cc1cccnc1)P(O)(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.54E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)				J Med Chem 50: 5967-75 (2007) Article DOI: 10.1021/jm0702884 BindingDB Entry DOI: 10.7270/Q27944DF
University of Southern California Curated by ChEMBL					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50225998 (2-chloro-3-(3-pyridinyl)-2-phosphonopropionic acid...) Show SMILES OC(=O)C(Cl)(Cc1cccnc1)P(O)(O)=O \|w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)				J Med Chem 50: 5967-75 (2007) Article DOI: 10.1021/jm0702884 BindingDB Entry DOI: 10.7270/Q27944DF
University of Southern California Curated by ChEMBL					More data for this Ligand-Target Pair
Farnesyl pyrophosphate synthase (Homo sapiens (Human))	BDBM50226000 (2-fluoro-3-(3-pyridinyl)-2-phosphonopropionic acid...) Show SMILES OC(=O)C(F)(Cc1cccnc1)P(O)(O)=O \|w:3.3\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>6.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern California Curated by ChEMBL					Assay Description Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3)				J Med Chem 50: 5967-75 (2007) Article DOI: 10.1021/jm0702884 BindingDB Entry DOI: 10.7270/Q27944DF
University of Southern California Curated by ChEMBL					More data for this Ligand-Target Pair

* indicates data uncertainty>20%